Deconstructing the evolution of metastasis

Información del proyecto

Evomet

Identificador del acuerdo de subvención: 955951

DOI

10.3030/955951

Proyecto cerrado

Fecha de la firma de la CE 3 Septiembre 2020

Fecha de inicio 1 Marzo 2021

Fecha de finalización 28 Febrero 2025

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total

€ 4 014 434,52

Aportación de la UE

€ 4 014 434,52

Coordinado por

FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)
Spain

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Documents, reports (4)

Final programme for the second annual meeting

Detailed programme for the second Evomet annual meeting including management training dissemination and communication activities

Final programme for the fourth annual meeting

Detailed programme for the fourth Evomet annual meeting, including management. training, dissemination and communication activities.

Final programme for the first annual meeting

Detailed programme for the first Evomet annual meeting including management training dissemination and communication activities

Final programme for the third annual meeting

Detailed programme for the third Evomet annual meeting, including management. training, dissemination and communication activities.

Websites, patent fillings, videos etc. (2)

Evomet website and logo

Visual image for Evomet and website published containing all information about the Evomet training network and its activities including recruitment

Motion graphics animations

Release of motion graphics videos highlighting the results of Evomet.

Open Research Data Pilot (1)

Data Management Plan

Containing all infromation on data management in the Evomet network

Other (1)

Supervisory Board of the Network

Supervisory board established and operative

Publicaciones

Peer reviewed articles (16)

The renal lineage factor PAX8 controls oncogenic signalling in kidney cancer

Autores: Patel SA, Hirosue S, Rodrigues P, Vojtasova E, Richardson EK, GE J, Syafruddin SE, Speed A, Papachristou EK, Baker D, Clarke D, Purvis S, Wesolowski L, Dyas A, Castillon L, Caraffini V, Bihary D, Yong C, Harrison DJ, Stewart GD, Machiela MJ, Purdue MP, Chanock SJ, Warren AY, Samarajiwa SA, Carroll JS & Vanharanta S
Publicado en: Nature, Edición 606, 2022, Página(s) 999-1006, ISSN 0028-0836
Editor: Nature Publishing Group
DOI: 10.1038/s41586-022-04809-8

Identifying predictors of treatment response and molecular changes induced by neoadjuvant chemotherapy and endocrine therapy in hormone receptor-positive/HER2-negative breast cancer: the NEOENDO translational study

Autores: F. Schettini, F. Brasó-Maristany, T. Pascual, N. Lorman-Carbó, S. Nucera, M. Bergamino, P. Galván, B. Conte, E. Seguí, I. García Fructuoso, R. Gómez Bravo, A.B. Rodríguez, O. Martínez-Sáez, N. Chic, M. Vidal, B. Adamo, B. González-Farre, E. Sanfeliu, I. Cebrecos, E. Mensión, G. Oses, M. Locci, M. Mollà, S. Ganau, P. Jares, S. Vidal-Sicart, M. Muñoz, A. Prat
Publicado en: ESMO Open, Edición 9, 2025, Página(s) 103989, ISSN 2059-7029
Editor: Elsevier BV
DOI: 10.1016/j.esmoop.2024.103989

A 14-gene B-cell immune signature in early-stage triple-negative breast cancer (TNBC): a pooled analysis of seven studies

Autores: Benedetta Conte, Fara Brasó-Maristany, Adela Rodríguez Hernández, Tomás Pascual, Guillermo Villacampa, Francesco Schettini, Maria J. Vidal Losada, Elia Seguí, Laura Angelats, Isabel Garcia-Fructuoso, Raquel Gómez-Bravo, Natàlia Lorman-Carbó, Laia Paré, Mercedes Marín-Aguilera, Olga Martínez-Sáez, Barbara Adamo, Esther Sanfeliu, Beatrice Fratini, Claudette Falato, Núria Chic, Ana Vivan
Publicado en: eBioMedicine, Edición 102, 2025, Página(s) 105043, ISSN 2352-3964
Editor: Elsevier BV
DOI: 10.1016/j.ebiom.2024.105043

The bacterial microbiome modulates the initiation of brain metastasis by impacting the gut-to-brain axis

Autores: Matteo Massara, Michelle Ballabio, Bastien Dolfi, Golnaz Morad, Vladimir Wischnewski, Eleni Lamprou, Joao Lourenco, Stéphanie Claudinot, Hector Gallart-Ayala, Rui Santalla Méndez, Annamaria Kauzlaric, Nadine Fournier, Ashish V. Damania, Matthew C. Wong, Julijana Ivanisevic, Nadim J. Ajami, Jennifer A. Wargo, Johanna A. Joyce
Publicado en: iScience, Edición 28, 2025, Página(s) 111874, ISSN 2589-0042
Editor: Elsevier BV
DOI: 10.1016/j.isci.2025.111874

MAF amplification licenses ERα through epigenetic remodelling to drive breast cancer metastasis

Autores: Alicia Llorente, María Teresa Blasco, Irene Espuny, Marc Guiu, Cecilia Ballaré, Enrique Blanco, Adrià Caballé, Anna Bellmunt, Fernando Salvador, Andrea Morales, Marc Nuñez, Guillem Loren, Francesca Imbastari, Marta Fidalgo, Cristina Figueras-Puig, Patrizia Gibler, Mariona Graupera, Freddy Monteiro, Antoni Riera, Ingunn Holen, Alexandra Avgustinova, Luciano Di Croce, Roger R. Gomis
Publicado en: Nature Cell Biology, Edición 25, 2023, Página(s) 1833-1847, ISSN 1465-7392
Editor: Nature Publishing Group
DOI: 10.1038/s41556-023-01281-y

The local microenvironment drives activation of neutrophils in human brain tumors

Autores: Roeltje R. Maas, Klara Soukup, Nadine Fournier, Matteo Massara, Sabine Galland, Mara Kornete, Vladimir Wischnewski, Joao Lourenco, Davide Croci, Ángel F. Álvarez-Prado, Damien N. Marie, Johanna Lilja, Rachel Marcone, Gabriel F. Calvo, Rui Santalla Mendez, Pauline Aubel, Leire Bejarano, Pratyaksha Wirapati, Iván Ballesteros, Andrés Hidalgo, Andreas F. Hottinger, Jean-Philippe Brouland, Roy T. D
Publicado en: Cell, Edición 186, 2024, Página(s) 4546-4566.e27, ISSN 0092-8674
Editor: Cell Press
DOI: 10.1016/j.cell.2023.08.043

Unraveling the clinicopathological and molecular changes induced by neoadjuvant chemotherapy and endocrine therapy in hormone receptor-positive/HER2-low and HER2-0 breast cancer

Autores: Francesco Schettini, Sabrina Nucera, Fara Brasó-Maristany, Irene De Santo, Tomás Pascual, Milana Bergamino, Patricia Galván, Benedetta Conte, Elia Seguí, Isabel García Fructuoso, Raquel Gómez Bravo, Pablo Rivera, Ana Belén Rodríguez, Olga Martínez-Sáez, Sergi Ganau, Esther Sanfeliu, Blanca González-Farre, Maria Vidal, Barbara Adamo, Isaac Cebrecos, Eduard Mension, Gabriela Oses, Pedro J
Publicado en: ESMO Open, 2024, ISSN 2059-7029
Editor: Elsevier
DOI: 10.1101/2023.12.27.23299114

The SWI/SNF complex member SMARCB1 supports lineage fidelity in kidney cancer

Autores: Ludovic Wesolowski, Jianfeng Ge, Leticia Castillon, Debora Sesia, Anna Dyas, Shoko Hirosue, Veronica Caraffini, Anne Y. Warren, Paulo Rodrigues, Giovanni Ciriello, Saroor A. Patel, Sakari Vanharanta
Publicado en: iScience, Edición 26, 2024, Página(s) 107360, ISSN 2589-0042
Editor: Elsevier BV
DOI: 10.1016/j.isci.2023.107360

TNBC-DX genomic test in early-stage triple-negative breast cancer treated with neoadjuvant taxane-based therapy

Autores: M. Martín, S.R. Stecklein, O. Gluz, G. Villacampa, M. Monte-Millán, U. Nitz, S. Cobo, M. Christgen, F. Brasó-Maristany, E.L. Álvarez, I. Echavarría, B. Conte, S. Kuemmel, C. Bueno-Muiño, Y. Jerez, R. Kates, M. Cebollero, C. Kolberg-Liedtke, O. Bueno, J.Á. García-Saenz, F. Moreno, E.-M. Grischke, H. Forstbauer, M. Braun, M. Warm, J. Hackmann, C. Uleer, B. Aktas, C. Schumacher, R. Wuerstlein
Publicado en: Annals of Oncology, Edición 36, 2025, Página(s) 158-171, ISSN 0923-7534
Editor: Oxford University Press
DOI: 10.1016/j.annonc.2024.10.012

Pericytes in the disease spotlight

Autores: Hielke van Splunder, Pilar Villacampa, Anabel Martínez-Romero, Mariona Graupera
Publicado en: Trends in Cell Biology, Edición 34, 2024, Página(s) 58-71, ISSN 0962-8924
Editor: Elsevier BV
DOI: 10.1016/j.tcb.2023.06.001

SNP of Aromatase Predict Long-term Survival and Aromatase Inhibitor Toxicity in Patients with Early Breast Cancer: A Biomarker Analysis of the GIM4 and GIM5 Trials

Autores: Benedetta Conte, Luca Boni, Giancarlo Bisagni, Antonio Durando, Giovanni Sanna, Stefania Gori, Ornella Garrone, Stefano Tamberi, Sabino De Placido, Francesco Schettini, Antonio Pazzola, Riccardo Ponzone, Filippo Montemurro, Gianluigi Lunardi, Rosario Notaro, Maria De Angioletti, Anna Turletti, Mauro Mansutti, Fabio Puglisi, Antonio Frassoldati, Mauro Porpiglia, Alessandra Fabi, Daniele Generali, G
Publicado en: Clinical Cancer Research, Edición 29, 2023, Página(s) 5217-5226, ISSN 1078-0432
Editor: American Association for Cancer Research
DOI: 10.1158/1078-0432.ccr-23-1568

Cancer cells impair monocyte-mediated T cell stimulation to evade immunity

Autores: Anais Elewaut, Guillem Estivill, Felix Bayerl, Leticia Castillon, Maria Novatchkova, Elisabeth Pottendorfer, Lisa Hoffmann-Haas, Martin Schönlein, Trung Viet Nguyen, Martin Lauss, Francesco Andreatta, Milica Vulin, Izabela Krecioch, Jonas Bayerl, Anna-Marie Pedde, Naomi Fabre, Felix Holstein, Shona M. Cronin, Sarah Rieser, Denarda Dangaj Laniti, David Barras, George Coukos, Camelia Quek, Xinyu Ba
Publicado en: Nature, Edición 637, 2025, Página(s) 716-725, ISSN 0028-0836
Editor: Nature Publishing Group
DOI: 10.1038/s41586-024-08257-4

Multispectral fluorine-19 MRI enables longitudinal and noninvasive monitoring of tumor-associated macrophages

Autores: Croci D, Santalla Mendez R, Temme S, Soukup K, Fournier N, Zomer N, Colotti R, Vischnewski V, Flogel U, van Heeswijk R, Joyce JA
Publicado en: Science Translational Medicine, Edición 14, 2022, ISSN 1946-6234
Editor: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.abo2952

Cancer cell plasticity during tumor progression, metastasis and response to therapy

Autores: Andrea Pérez-González, Kevin Bévant & Cédric Blanpain
Publicado en: Nature Cancer, Edición 2023, Aug 3, 2023, ISSN 2662-1347
Editor: Springer Nature
DOI: 10.1038/s43018-023-00595-y

HER2DX ERBB2 mRNA expression in advanced HER2-positive breast cancer treated with T-DM1

Autores: Fara Brasó-Maristany, Gaia Griguolo, Nuria Chic, Tomás Pascual, Laia Paré, Julia Maues, Patricia Galván, Maria Vittoria Dieci, Federica Miglietta, Tommaso Giarratano, Olga Martínez-Sáez, Mercedes Marín-Aguilera, Francesco Schettini, Benedetta Conte, Laura Angelats, Maria Vidal, Barbara Adamo, Montserrat Muñoz, Esther Sanfeliu, Blanca González, Ana Vivancos, Patricia Villagrasa, Joel S Par
Publicado en: JNCI: Journal of the National Cancer Institute, Edición 115, 2023, Página(s) 332-336, ISSN 0027-8874
Editor: Oxford University Press
DOI: 10.1093/jnci/djac227

Efficacy of adjuvant chemotherapy schedules for breast cancer according to body mass index: results from the phase III GIM2 trial

Autores: F. Poggio, E. Blondeaux, M. Tagliamento, M. Perachino, S. Nardin, B. Conte, M. Giuliano, G. Arpino, M. De Laurentiis, A. Gravina, G. Bisagni, A. Rimanti, A. Turletti, C. Nisticò, E. Magnolfi, S. Gasparro, A. Fabi, O. Garrone, M.G. Alicicco, Y. Urracci, P. Poletti, P. Correale, C. Molinelli, A. Fozza, F. Puglisi, G. Colantuoni, P. Fregatti, L. Boni, M. Lambertini, L. Del Mastro
Publicado en: ESMO Open, Edición 9, 2025, Página(s) 103650, ISSN 2059-7029
Editor: Elsevier BV
DOI: 10.1016/j.esmoop.2024.103650