Deconstructing the evolution of metastasis

Informations projet

Evomet

N° de convention de subvention: 955951

DOI

10.3030/955951

Projet clôturé

Date de signature de la CE 3 Septembre 2020

Date de début 1 Mars 2021

Date de fin 28 Février 2025

Financé au titre de

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coût total

€ 4 014 434,52

Contribution de l’UE

€ 4 014 434,52

Coordonné par

FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)
Spain

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Documents, reports (4)

Final programme for the second annual meeting

Detailed programme for the second Evomet annual meeting including management training dissemination and communication activities

Final programme for the fourth annual meeting

Detailed programme for the fourth Evomet annual meeting, including management. training, dissemination and communication activities.

Final programme for the first annual meeting

Detailed programme for the first Evomet annual meeting including management training dissemination and communication activities

Final programme for the third annual meeting

Detailed programme for the third Evomet annual meeting, including management. training, dissemination and communication activities.

Websites, patent fillings, videos etc. (2)

Evomet website and logo

Visual image for Evomet and website published containing all information about the Evomet training network and its activities including recruitment

Motion graphics animations

Release of motion graphics videos highlighting the results of Evomet.

Open Research Data Pilot (1)

Data Management Plan

Containing all infromation on data management in the Evomet network

Other (1)

Supervisory Board of the Network

Supervisory board established and operative

Publications

Peer reviewed articles (16)

The renal lineage factor PAX8 controls oncogenic signalling in kidney cancer

Auteurs: Patel SA, Hirosue S, Rodrigues P, Vojtasova E, Richardson EK, GE J, Syafruddin SE, Speed A, Papachristou EK, Baker D, Clarke D, Purvis S, Wesolowski L, Dyas A, Castillon L, Caraffini V, Bihary D, Yong C, Harrison DJ, Stewart GD, Machiela MJ, Purdue MP, Chanock SJ, Warren AY, Samarajiwa SA, Carroll JS & Vanharanta S
Publié dans: Nature, Numéro 606, 2022, Page(s) 999-1006, ISSN 0028-0836
Éditeur: Nature Publishing Group
DOI: 10.1038/s41586-022-04809-8

Identifying predictors of treatment response and molecular changes induced by neoadjuvant chemotherapy and endocrine therapy in hormone receptor-positive/HER2-negative breast cancer: the NEOENDO translational study

Auteurs: F. Schettini, F. Brasó-Maristany, T. Pascual, N. Lorman-Carbó, S. Nucera, M. Bergamino, P. Galván, B. Conte, E. Seguí, I. García Fructuoso, R. Gómez Bravo, A.B. Rodríguez, O. Martínez-Sáez, N. Chic, M. Vidal, B. Adamo, B. González-Farre, E. Sanfeliu, I. Cebrecos, E. Mensión, G. Oses, M. Locci, M. Mollà, S. Ganau, P. Jares, S. Vidal-Sicart, M. Muñoz, A. Prat
Publié dans: ESMO Open, Numéro 9, 2025, Page(s) 103989, ISSN 2059-7029
Éditeur: Elsevier BV
DOI: 10.1016/j.esmoop.2024.103989

A 14-gene B-cell immune signature in early-stage triple-negative breast cancer (TNBC): a pooled analysis of seven studies

Auteurs: Benedetta Conte, Fara Brasó-Maristany, Adela Rodríguez Hernández, Tomás Pascual, Guillermo Villacampa, Francesco Schettini, Maria J. Vidal Losada, Elia Seguí, Laura Angelats, Isabel Garcia-Fructuoso, Raquel Gómez-Bravo, Natàlia Lorman-Carbó, Laia Paré, Mercedes Marín-Aguilera, Olga Martínez-Sáez, Barbara Adamo, Esther Sanfeliu, Beatrice Fratini, Claudette Falato, Núria Chic, Ana Vivan
Publié dans: eBioMedicine, Numéro 102, 2025, Page(s) 105043, ISSN 2352-3964
Éditeur: Elsevier BV
DOI: 10.1016/j.ebiom.2024.105043

The bacterial microbiome modulates the initiation of brain metastasis by impacting the gut-to-brain axis

Auteurs: Matteo Massara, Michelle Ballabio, Bastien Dolfi, Golnaz Morad, Vladimir Wischnewski, Eleni Lamprou, Joao Lourenco, Stéphanie Claudinot, Hector Gallart-Ayala, Rui Santalla Méndez, Annamaria Kauzlaric, Nadine Fournier, Ashish V. Damania, Matthew C. Wong, Julijana Ivanisevic, Nadim J. Ajami, Jennifer A. Wargo, Johanna A. Joyce
Publié dans: iScience, Numéro 28, 2025, Page(s) 111874, ISSN 2589-0042
Éditeur: Elsevier BV
DOI: 10.1016/j.isci.2025.111874

MAF amplification licenses ERα through epigenetic remodelling to drive breast cancer metastasis

Auteurs: Alicia Llorente, María Teresa Blasco, Irene Espuny, Marc Guiu, Cecilia Ballaré, Enrique Blanco, Adrià Caballé, Anna Bellmunt, Fernando Salvador, Andrea Morales, Marc Nuñez, Guillem Loren, Francesca Imbastari, Marta Fidalgo, Cristina Figueras-Puig, Patrizia Gibler, Mariona Graupera, Freddy Monteiro, Antoni Riera, Ingunn Holen, Alexandra Avgustinova, Luciano Di Croce, Roger R. Gomis
Publié dans: Nature Cell Biology, Numéro 25, 2023, Page(s) 1833-1847, ISSN 1465-7392
Éditeur: Nature Publishing Group
DOI: 10.1038/s41556-023-01281-y

The local microenvironment drives activation of neutrophils in human brain tumors

Auteurs: Roeltje R. Maas, Klara Soukup, Nadine Fournier, Matteo Massara, Sabine Galland, Mara Kornete, Vladimir Wischnewski, Joao Lourenco, Davide Croci, Ángel F. Álvarez-Prado, Damien N. Marie, Johanna Lilja, Rachel Marcone, Gabriel F. Calvo, Rui Santalla Mendez, Pauline Aubel, Leire Bejarano, Pratyaksha Wirapati, Iván Ballesteros, Andrés Hidalgo, Andreas F. Hottinger, Jean-Philippe Brouland, Roy T. D
Publié dans: Cell, Numéro 186, 2024, Page(s) 4546-4566.e27, ISSN 0092-8674
Éditeur: Cell Press
DOI: 10.1016/j.cell.2023.08.043

Unraveling the clinicopathological and molecular changes induced by neoadjuvant chemotherapy and endocrine therapy in hormone receptor-positive/HER2-low and HER2-0 breast cancer

Auteurs: Francesco Schettini, Sabrina Nucera, Fara Brasó-Maristany, Irene De Santo, Tomás Pascual, Milana Bergamino, Patricia Galván, Benedetta Conte, Elia Seguí, Isabel García Fructuoso, Raquel Gómez Bravo, Pablo Rivera, Ana Belén Rodríguez, Olga Martínez-Sáez, Sergi Ganau, Esther Sanfeliu, Blanca González-Farre, Maria Vidal, Barbara Adamo, Isaac Cebrecos, Eduard Mension, Gabriela Oses, Pedro J
Publié dans: ESMO Open, 2024, ISSN 2059-7029
Éditeur: Elsevier
DOI: 10.1101/2023.12.27.23299114

The SWI/SNF complex member SMARCB1 supports lineage fidelity in kidney cancer

Auteurs: Ludovic Wesolowski, Jianfeng Ge, Leticia Castillon, Debora Sesia, Anna Dyas, Shoko Hirosue, Veronica Caraffini, Anne Y. Warren, Paulo Rodrigues, Giovanni Ciriello, Saroor A. Patel, Sakari Vanharanta
Publié dans: iScience, Numéro 26, 2024, Page(s) 107360, ISSN 2589-0042
Éditeur: Elsevier BV
DOI: 10.1016/j.isci.2023.107360

TNBC-DX genomic test in early-stage triple-negative breast cancer treated with neoadjuvant taxane-based therapy

Auteurs: M. Martín, S.R. Stecklein, O. Gluz, G. Villacampa, M. Monte-Millán, U. Nitz, S. Cobo, M. Christgen, F. Brasó-Maristany, E.L. Álvarez, I. Echavarría, B. Conte, S. Kuemmel, C. Bueno-Muiño, Y. Jerez, R. Kates, M. Cebollero, C. Kolberg-Liedtke, O. Bueno, J.Á. García-Saenz, F. Moreno, E.-M. Grischke, H. Forstbauer, M. Braun, M. Warm, J. Hackmann, C. Uleer, B. Aktas, C. Schumacher, R. Wuerstlein
Publié dans: Annals of Oncology, Numéro 36, 2025, Page(s) 158-171, ISSN 0923-7534
Éditeur: Oxford University Press
DOI: 10.1016/j.annonc.2024.10.012

Pericytes in the disease spotlight

Auteurs: Hielke van Splunder, Pilar Villacampa, Anabel Martínez-Romero, Mariona Graupera
Publié dans: Trends in Cell Biology, Numéro 34, 2024, Page(s) 58-71, ISSN 0962-8924
Éditeur: Elsevier BV
DOI: 10.1016/j.tcb.2023.06.001

SNP of Aromatase Predict Long-term Survival and Aromatase Inhibitor Toxicity in Patients with Early Breast Cancer: A Biomarker Analysis of the GIM4 and GIM5 Trials

Auteurs: Benedetta Conte, Luca Boni, Giancarlo Bisagni, Antonio Durando, Giovanni Sanna, Stefania Gori, Ornella Garrone, Stefano Tamberi, Sabino De Placido, Francesco Schettini, Antonio Pazzola, Riccardo Ponzone, Filippo Montemurro, Gianluigi Lunardi, Rosario Notaro, Maria De Angioletti, Anna Turletti, Mauro Mansutti, Fabio Puglisi, Antonio Frassoldati, Mauro Porpiglia, Alessandra Fabi, Daniele Generali, G
Publié dans: Clinical Cancer Research, Numéro 29, 2023, Page(s) 5217-5226, ISSN 1078-0432
Éditeur: American Association for Cancer Research
DOI: 10.1158/1078-0432.ccr-23-1568

Cancer cells impair monocyte-mediated T cell stimulation to evade immunity

Auteurs: Anais Elewaut, Guillem Estivill, Felix Bayerl, Leticia Castillon, Maria Novatchkova, Elisabeth Pottendorfer, Lisa Hoffmann-Haas, Martin Schönlein, Trung Viet Nguyen, Martin Lauss, Francesco Andreatta, Milica Vulin, Izabela Krecioch, Jonas Bayerl, Anna-Marie Pedde, Naomi Fabre, Felix Holstein, Shona M. Cronin, Sarah Rieser, Denarda Dangaj Laniti, David Barras, George Coukos, Camelia Quek, Xinyu Ba
Publié dans: Nature, Numéro 637, 2025, Page(s) 716-725, ISSN 0028-0836
Éditeur: Nature Publishing Group
DOI: 10.1038/s41586-024-08257-4

Multispectral fluorine-19 MRI enables longitudinal and noninvasive monitoring of tumor-associated macrophages

Auteurs: Croci D, Santalla Mendez R, Temme S, Soukup K, Fournier N, Zomer N, Colotti R, Vischnewski V, Flogel U, van Heeswijk R, Joyce JA
Publié dans: Science Translational Medicine, Numéro 14, 2022, ISSN 1946-6234
Éditeur: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.abo2952

Cancer cell plasticity during tumor progression, metastasis and response to therapy

Auteurs: Andrea Pérez-González, Kevin Bévant & Cédric Blanpain
Publié dans: Nature Cancer, Numéro 2023, Aug 3, 2023, ISSN 2662-1347
Éditeur: Springer Nature
DOI: 10.1038/s43018-023-00595-y

HER2DX ERBB2 mRNA expression in advanced HER2-positive breast cancer treated with T-DM1

Auteurs: Fara Brasó-Maristany, Gaia Griguolo, Nuria Chic, Tomás Pascual, Laia Paré, Julia Maues, Patricia Galván, Maria Vittoria Dieci, Federica Miglietta, Tommaso Giarratano, Olga Martínez-Sáez, Mercedes Marín-Aguilera, Francesco Schettini, Benedetta Conte, Laura Angelats, Maria Vidal, Barbara Adamo, Montserrat Muñoz, Esther Sanfeliu, Blanca González, Ana Vivancos, Patricia Villagrasa, Joel S Par
Publié dans: JNCI: Journal of the National Cancer Institute, Numéro 115, 2023, Page(s) 332-336, ISSN 0027-8874
Éditeur: Oxford University Press
DOI: 10.1093/jnci/djac227

Efficacy of adjuvant chemotherapy schedules for breast cancer according to body mass index: results from the phase III GIM2 trial

Auteurs: F. Poggio, E. Blondeaux, M. Tagliamento, M. Perachino, S. Nardin, B. Conte, M. Giuliano, G. Arpino, M. De Laurentiis, A. Gravina, G. Bisagni, A. Rimanti, A. Turletti, C. Nisticò, E. Magnolfi, S. Gasparro, A. Fabi, O. Garrone, M.G. Alicicco, Y. Urracci, P. Poletti, P. Correale, C. Molinelli, A. Fozza, F. Puglisi, G. Colantuoni, P. Fregatti, L. Boni, M. Lambertini, L. Del Mastro
Publié dans: ESMO Open, Numéro 9, 2025, Page(s) 103650, ISSN 2059-7029
Éditeur: Elsevier BV
DOI: 10.1016/j.esmoop.2024.103650