Deconstructing the evolution of metastasis

Informazioni relative al progetto

Evomet

ID dell’accordo di sovvenzione: 955951

DOI

10.3030/955951

Progetto chiuso

Data della firma CE 3 Settembre 2020

Data di avvio 1 Marzo 2021

Data di completamento 28 Febbraio 2025

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale

€ 4 014 434,52

Contributo UE

€ 4 014 434,52

Coordinato da

FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)
Spain

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (4)

Final programme for the second annual meeting

Detailed programme for the second Evomet annual meeting including management training dissemination and communication activities

Final programme for the fourth annual meeting

Detailed programme for the fourth Evomet annual meeting, including management. training, dissemination and communication activities.

Final programme for the first annual meeting

Detailed programme for the first Evomet annual meeting including management training dissemination and communication activities

Final programme for the third annual meeting

Detailed programme for the third Evomet annual meeting, including management. training, dissemination and communication activities.

Websites, patent fillings, videos etc. (2)

Evomet website and logo

Visual image for Evomet and website published containing all information about the Evomet training network and its activities including recruitment

Motion graphics animations

Release of motion graphics videos highlighting the results of Evomet.

Open Research Data Pilot (1)

Data Management Plan

Containing all infromation on data management in the Evomet network

Other (1)

Supervisory Board of the Network

Supervisory board established and operative

Pubblicazioni

Peer reviewed articles (16)

The renal lineage factor PAX8 controls oncogenic signalling in kidney cancer

Autori: Patel SA, Hirosue S, Rodrigues P, Vojtasova E, Richardson EK, GE J, Syafruddin SE, Speed A, Papachristou EK, Baker D, Clarke D, Purvis S, Wesolowski L, Dyas A, Castillon L, Caraffini V, Bihary D, Yong C, Harrison DJ, Stewart GD, Machiela MJ, Purdue MP, Chanock SJ, Warren AY, Samarajiwa SA, Carroll JS & Vanharanta S
Pubblicato in: Nature, Numero 606, 2022, Pagina/e 999-1006, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-022-04809-8

Identifying predictors of treatment response and molecular changes induced by neoadjuvant chemotherapy and endocrine therapy in hormone receptor-positive/HER2-negative breast cancer: the NEOENDO translational study

Autori: F. Schettini, F. Brasó-Maristany, T. Pascual, N. Lorman-Carbó, S. Nucera, M. Bergamino, P. Galván, B. Conte, E. Seguí, I. García Fructuoso, R. Gómez Bravo, A.B. Rodríguez, O. Martínez-Sáez, N. Chic, M. Vidal, B. Adamo, B. González-Farre, E. Sanfeliu, I. Cebrecos, E. Mensión, G. Oses, M. Locci, M. Mollà, S. Ganau, P. Jares, S. Vidal-Sicart, M. Muñoz, A. Prat
Pubblicato in: ESMO Open, Numero 9, 2025, Pagina/e 103989, ISSN 2059-7029
Editore: Elsevier BV
DOI: 10.1016/j.esmoop.2024.103989

A 14-gene B-cell immune signature in early-stage triple-negative breast cancer (TNBC): a pooled analysis of seven studies

Autori: Benedetta Conte, Fara Brasó-Maristany, Adela Rodríguez Hernández, Tomás Pascual, Guillermo Villacampa, Francesco Schettini, Maria J. Vidal Losada, Elia Seguí, Laura Angelats, Isabel Garcia-Fructuoso, Raquel Gómez-Bravo, Natàlia Lorman-Carbó, Laia Paré, Mercedes Marín-Aguilera, Olga Martínez-Sáez, Barbara Adamo, Esther Sanfeliu, Beatrice Fratini, Claudette Falato, Núria Chic, Ana Vivan
Pubblicato in: eBioMedicine, Numero 102, 2025, Pagina/e 105043, ISSN 2352-3964
Editore: Elsevier BV
DOI: 10.1016/j.ebiom.2024.105043

The bacterial microbiome modulates the initiation of brain metastasis by impacting the gut-to-brain axis

Autori: Matteo Massara, Michelle Ballabio, Bastien Dolfi, Golnaz Morad, Vladimir Wischnewski, Eleni Lamprou, Joao Lourenco, Stéphanie Claudinot, Hector Gallart-Ayala, Rui Santalla Méndez, Annamaria Kauzlaric, Nadine Fournier, Ashish V. Damania, Matthew C. Wong, Julijana Ivanisevic, Nadim J. Ajami, Jennifer A. Wargo, Johanna A. Joyce
Pubblicato in: iScience, Numero 28, 2025, Pagina/e 111874, ISSN 2589-0042
Editore: Elsevier BV
DOI: 10.1016/j.isci.2025.111874

MAF amplification licenses ERα through epigenetic remodelling to drive breast cancer metastasis

Autori: Alicia Llorente, María Teresa Blasco, Irene Espuny, Marc Guiu, Cecilia Ballaré, Enrique Blanco, Adrià Caballé, Anna Bellmunt, Fernando Salvador, Andrea Morales, Marc Nuñez, Guillem Loren, Francesca Imbastari, Marta Fidalgo, Cristina Figueras-Puig, Patrizia Gibler, Mariona Graupera, Freddy Monteiro, Antoni Riera, Ingunn Holen, Alexandra Avgustinova, Luciano Di Croce, Roger R. Gomis
Pubblicato in: Nature Cell Biology, Numero 25, 2023, Pagina/e 1833-1847, ISSN 1465-7392
Editore: Nature Publishing Group
DOI: 10.1038/s41556-023-01281-y

The local microenvironment drives activation of neutrophils in human brain tumors

Autori: Roeltje R. Maas, Klara Soukup, Nadine Fournier, Matteo Massara, Sabine Galland, Mara Kornete, Vladimir Wischnewski, Joao Lourenco, Davide Croci, Ángel F. Álvarez-Prado, Damien N. Marie, Johanna Lilja, Rachel Marcone, Gabriel F. Calvo, Rui Santalla Mendez, Pauline Aubel, Leire Bejarano, Pratyaksha Wirapati, Iván Ballesteros, Andrés Hidalgo, Andreas F. Hottinger, Jean-Philippe Brouland, Roy T. D
Pubblicato in: Cell, Numero 186, 2024, Pagina/e 4546-4566.e27, ISSN 0092-8674
Editore: Cell Press
DOI: 10.1016/j.cell.2023.08.043

Unraveling the clinicopathological and molecular changes induced by neoadjuvant chemotherapy and endocrine therapy in hormone receptor-positive/HER2-low and HER2-0 breast cancer

Autori: Francesco Schettini, Sabrina Nucera, Fara Brasó-Maristany, Irene De Santo, Tomás Pascual, Milana Bergamino, Patricia Galván, Benedetta Conte, Elia Seguí, Isabel García Fructuoso, Raquel Gómez Bravo, Pablo Rivera, Ana Belén Rodríguez, Olga Martínez-Sáez, Sergi Ganau, Esther Sanfeliu, Blanca González-Farre, Maria Vidal, Barbara Adamo, Isaac Cebrecos, Eduard Mension, Gabriela Oses, Pedro J
Pubblicato in: ESMO Open, 2024, ISSN 2059-7029
Editore: Elsevier
DOI: 10.1101/2023.12.27.23299114

The SWI/SNF complex member SMARCB1 supports lineage fidelity in kidney cancer

Autori: Ludovic Wesolowski, Jianfeng Ge, Leticia Castillon, Debora Sesia, Anna Dyas, Shoko Hirosue, Veronica Caraffini, Anne Y. Warren, Paulo Rodrigues, Giovanni Ciriello, Saroor A. Patel, Sakari Vanharanta
Pubblicato in: iScience, Numero 26, 2024, Pagina/e 107360, ISSN 2589-0042
Editore: Elsevier BV
DOI: 10.1016/j.isci.2023.107360

TNBC-DX genomic test in early-stage triple-negative breast cancer treated with neoadjuvant taxane-based therapy

Autori: M. Martín, S.R. Stecklein, O. Gluz, G. Villacampa, M. Monte-Millán, U. Nitz, S. Cobo, M. Christgen, F. Brasó-Maristany, E.L. Álvarez, I. Echavarría, B. Conte, S. Kuemmel, C. Bueno-Muiño, Y. Jerez, R. Kates, M. Cebollero, C. Kolberg-Liedtke, O. Bueno, J.Á. García-Saenz, F. Moreno, E.-M. Grischke, H. Forstbauer, M. Braun, M. Warm, J. Hackmann, C. Uleer, B. Aktas, C. Schumacher, R. Wuerstlein
Pubblicato in: Annals of Oncology, Numero 36, 2025, Pagina/e 158-171, ISSN 0923-7534
Editore: Oxford University Press
DOI: 10.1016/j.annonc.2024.10.012

Pericytes in the disease spotlight

Autori: Hielke van Splunder, Pilar Villacampa, Anabel Martínez-Romero, Mariona Graupera
Pubblicato in: Trends in Cell Biology, Numero 34, 2024, Pagina/e 58-71, ISSN 0962-8924
Editore: Elsevier BV
DOI: 10.1016/j.tcb.2023.06.001

SNP of Aromatase Predict Long-term Survival and Aromatase Inhibitor Toxicity in Patients with Early Breast Cancer: A Biomarker Analysis of the GIM4 and GIM5 Trials

Autori: Benedetta Conte, Luca Boni, Giancarlo Bisagni, Antonio Durando, Giovanni Sanna, Stefania Gori, Ornella Garrone, Stefano Tamberi, Sabino De Placido, Francesco Schettini, Antonio Pazzola, Riccardo Ponzone, Filippo Montemurro, Gianluigi Lunardi, Rosario Notaro, Maria De Angioletti, Anna Turletti, Mauro Mansutti, Fabio Puglisi, Antonio Frassoldati, Mauro Porpiglia, Alessandra Fabi, Daniele Generali, G
Pubblicato in: Clinical Cancer Research, Numero 29, 2023, Pagina/e 5217-5226, ISSN 1078-0432
Editore: American Association for Cancer Research
DOI: 10.1158/1078-0432.ccr-23-1568

Cancer cells impair monocyte-mediated T cell stimulation to evade immunity

Autori: Anais Elewaut, Guillem Estivill, Felix Bayerl, Leticia Castillon, Maria Novatchkova, Elisabeth Pottendorfer, Lisa Hoffmann-Haas, Martin Schönlein, Trung Viet Nguyen, Martin Lauss, Francesco Andreatta, Milica Vulin, Izabela Krecioch, Jonas Bayerl, Anna-Marie Pedde, Naomi Fabre, Felix Holstein, Shona M. Cronin, Sarah Rieser, Denarda Dangaj Laniti, David Barras, George Coukos, Camelia Quek, Xinyu Ba
Pubblicato in: Nature, Numero 637, 2025, Pagina/e 716-725, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-024-08257-4

Multispectral fluorine-19 MRI enables longitudinal and noninvasive monitoring of tumor-associated macrophages

Autori: Croci D, Santalla Mendez R, Temme S, Soukup K, Fournier N, Zomer N, Colotti R, Vischnewski V, Flogel U, van Heeswijk R, Joyce JA
Pubblicato in: Science Translational Medicine, Numero 14, 2022, ISSN 1946-6234
Editore: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.abo2952

Cancer cell plasticity during tumor progression, metastasis and response to therapy

Autori: Andrea Pérez-González, Kevin Bévant & Cédric Blanpain
Pubblicato in: Nature Cancer, Numero 2023, Aug 3, 2023, ISSN 2662-1347
Editore: Springer Nature
DOI: 10.1038/s43018-023-00595-y

HER2DX ERBB2 mRNA expression in advanced HER2-positive breast cancer treated with T-DM1

Autori: Fara Brasó-Maristany, Gaia Griguolo, Nuria Chic, Tomás Pascual, Laia Paré, Julia Maues, Patricia Galván, Maria Vittoria Dieci, Federica Miglietta, Tommaso Giarratano, Olga Martínez-Sáez, Mercedes Marín-Aguilera, Francesco Schettini, Benedetta Conte, Laura Angelats, Maria Vidal, Barbara Adamo, Montserrat Muñoz, Esther Sanfeliu, Blanca González, Ana Vivancos, Patricia Villagrasa, Joel S Par
Pubblicato in: JNCI: Journal of the National Cancer Institute, Numero 115, 2023, Pagina/e 332-336, ISSN 0027-8874
Editore: Oxford University Press
DOI: 10.1093/jnci/djac227

Efficacy of adjuvant chemotherapy schedules for breast cancer according to body mass index: results from the phase III GIM2 trial

Autori: F. Poggio, E. Blondeaux, M. Tagliamento, M. Perachino, S. Nardin, B. Conte, M. Giuliano, G. Arpino, M. De Laurentiis, A. Gravina, G. Bisagni, A. Rimanti, A. Turletti, C. Nisticò, E. Magnolfi, S. Gasparro, A. Fabi, O. Garrone, M.G. Alicicco, Y. Urracci, P. Poletti, P. Correale, C. Molinelli, A. Fozza, F. Puglisi, G. Colantuoni, P. Fregatti, L. Boni, M. Lambertini, L. Del Mastro
Pubblicato in: ESMO Open, Numero 9, 2025, Pagina/e 103650, ISSN 2059-7029
Editore: Elsevier BV
DOI: 10.1016/j.esmoop.2024.103650