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Understanding (harmful) virus-host interactions by linking virology and bioinformatics

Descripción del proyecto

Vinculación de la virología y la bioinformática para comprender los virus y sus interacciones con los hospedadores

Los virus representan una de las principales amenazas potenciales para la población mundial en constante crecimiento y envejecimiento. Sin embargo, a pesar del papel de los virus como patógenos humanos y animales, su mutualismo, comensalismo o parasitismo aún no se han aclarado por completo. La característica principal del proyecto VIROINF, financiado con fondos europeos, es su carácter interdisciplinario, que reúne a virólogos y bioinformáticos para desarrollar herramientas bioinformáticas para su aplicación en estudios de modelos virológicos pertinentes. El objetivo es permitir una mejor comprensión de los virus y sus interacciones con los hospedadores, lo que proporcionará a los virólogos nuevas herramientas para analizar los virus de nueva aparición y los ya conocidos. VIROINF proporcionará estrategias novedosas para tratar enfermedades y controlar la propagación de las virosis. El programa de investigación incluirá la formación de una nueva generación de científicos con competencias avanzadas en virología y bioinformática.

Objetivo

Viruses are currently at the forefront of scientific priorities of many national research councils and the EU. Viruses will remain an urgent topic given the continuously growing and aging global population, creating major challenges for health science, technology and society as a whole. Besides their important role as human and animal pathogens, the beneficial, commensal or harmful functions of viruses are poorly understood. Fundamental questions in virology can only be tackled with the help of bioinformatics. However, the required sophisticated bioinformatics tools are not readily available.

By developing and applying tailored bioinformatical tools in important virological models, this ITN, called VIROINF, will provide a better understanding of viruses and the interaction with their hosts, with the aim of giving virologists potent new `weapons' to fight against emerging and established viruses. VIROINF will open the door to develop novel strategies to better understand, treat, and control viral diseases, in addition to understanding the broader ecology and evolution of viruses. The key feature of VIROINF is its interdisciplinary nature, which brings together virologists and bioinformaticians to achieve common goals.

The research programme will train a badly needed new generation of young scientists with excellent understanding and skills in virology, cell biology and bioinformatics, to the great benefit and advancement of the field. VIROINF is unique by its special triple supervision in two distinct subjects (virology and bioinformatics) from at least two organisations. Our ESRs will be trained at the very forefront of this rapidly developing field, by gaining state-of-the-art insights into both theoretical and empirical science. The ESRs will be in an ideal position to encourage the bioinformatical development of the field in academia, or by implementing their knowledge to solve practical problems in the non-academic sector.

Coordinador

FRIEDRICH-SCHILLER-UNIVERSITÄT JENA
Aportación neta de la UEn
€ 252 788,40
Dirección
FÜRSTENGRABEN 1
07743 JENA
Alemania

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Región
Thüringen Thüringen Jena, Kreisfreie Stadt
Tipo de actividad
Higher or Secondary Education Establishments
Enlaces
Coste total
€ 252 788,40

Participantes (15)