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Understanding (harmful) virus-host interactions by linking virology and bioinformatics

Descrizione del progetto

Collegare la virologia e la bioinformatica per comprendere i virus e le loro interazioni con gli organismi ospiti

I virus rappresentano una delle principali potenziali minacce per una popolazione globale che continua a crescere e a invecchiare. Tuttavia, nonostante sia chiaro il ruolo dei virus come patogeni umani e animali, non sono state ancora chiarite appieno le loro funzioni benefiche, commensali o dannose. La caratteristica principale del progetto VIROINF, finanziato dall’UE, è la sua natura interdisciplinare, che riunisce virologi e bioinformatici per sviluppare strumenti bioinformatici da applicare allo studio di modelli virologici pertinenti. L’obiettivo è quello di permettere una migliore comprensione dei virus e della loro interazione con l’organismo ospite, offrendo ai virologi nuovi strumenti per analizzare virus emergenti e conosciuti. VIROINF fornirà nuove strategie per trattare le malattie e controllare la diffusione delle infezioni virali. Il programma di ricerca includerà la formazione di una nuova generazione di scienziati con competenze avanzate in virologia e bioinformatica.

Obiettivo

Viruses are currently at the forefront of scientific priorities of many national research councils and the EU. Viruses will remain an urgent topic given the continuously growing and aging global population, creating major challenges for health science, technology and society as a whole. Besides their important role as human and animal pathogens, the beneficial, commensal or harmful functions of viruses are poorly understood. Fundamental questions in virology can only be tackled with the help of bioinformatics. However, the required sophisticated bioinformatics tools are not readily available.

By developing and applying tailored bioinformatical tools in important virological models, this ITN, called VIROINF, will provide a better understanding of viruses and the interaction with their hosts, with the aim of giving virologists potent new `weapons' to fight against emerging and established viruses. VIROINF will open the door to develop novel strategies to better understand, treat, and control viral diseases, in addition to understanding the broader ecology and evolution of viruses. The key feature of VIROINF is its interdisciplinary nature, which brings together virologists and bioinformaticians to achieve common goals.

The research programme will train a badly needed new generation of young scientists with excellent understanding and skills in virology, cell biology and bioinformatics, to the great benefit and advancement of the field. VIROINF is unique by its special triple supervision in two distinct subjects (virology and bioinformatics) from at least two organisations. Our ESRs will be trained at the very forefront of this rapidly developing field, by gaining state-of-the-art insights into both theoretical and empirical science. The ESRs will be in an ideal position to encourage the bioinformatical development of the field in academia, or by implementing their knowledge to solve practical problems in the non-academic sector.

Coordinatore

FRIEDRICH-SCHILLER-UNIVERSITÄT JENA
Contribution nette de l'UE
€ 252 788,40
Indirizzo
FÜRSTENGRABEN 1
07743 JENA
Germania

Mostra sulla mappa

Regione
Thüringen Thüringen Jena, Kreisfreie Stadt
Tipo di attività
Higher or Secondary Education Establishments
Collegamenti
Costo totale
€ 252 788,40

Partecipanti (15)