Descripción del proyecto
Empoderamiento de la próxima generación de neurobiólogos
El encéfalo es el órgano más complejo del cuerpo humano: recibe información del entorno y la incorpora en la planificación y ejecución de las acciones apropiadas. Sin embargo, se desconocen en gran medida los principios de comunicación entre las diferentes áreas del encéfalo para combinar los estímulos sensoriales con el control motor y las funciones ejecutivas. El objetivo del proyecto In2PrimateBrains, financiado con fondos europeos, es colmar esta brecha del conocimiento mediante la formación de la próxima generación de investigadores utilizando metodologías de vanguardia en los sectores académico, clínico e industrial para apoyar las futuras investigaciones en este campo. Los alumnos estudiarán el encéfalo de los primates no humanos —el modelo más cercano al de los seres humanos— lo que ayudará a comprender las dinámicas locales y de largo alcance de la comunicación hasta la neurona.
Objetivo
In2PrimateBrains proposes a highly competitive training-through-research program dedicated to the study of neuronal intra- and
inter-areal communication in non-human primate (NHP) brains. This program will empower the next generation of
researchers with best practices and cutting edge methodologies for studying complex neuronal activity from multiple brain
areas and across cortical layers. Our core scientific goals are to identify common and specific bottom-up and top-down
communication principles across NHP brain networks for vision, motor control and executive functions. These functions are
especially well developed in primates, and we propose to study them in a brain model as close as possible to the human
brain: the NHP brain. Critically, detailed insights into the local- and long-range dynamics of communication, down to the
single-neuron level and at millisecond precision, necessitate invasive recording, stimulation and inactivation techniques
precluding human investigations. The project entails 9 work packages with well-defined tasks to ensure success in our
research and training objectives. We propose tailored research training by world-leading European researchers from the
academic, clinical and industrial sectors. This will be accompanied by a comprehensive program of network-wide training
events including thematic workshops in essential research-related skills and soft-skill training sessions to ensure successful
careers in public or private sectors. The direct experience and acquired expertise in state-of-the-art NHP research and
technology development in different environments will drive our ESRs to pursue international, interdisciplinary and
intersectoral careers. In a highly competitive international environment, In2PrimateBrains will ensure that Europe remains at the
forefront of primate brain research in health and disease with scientists trained by the highest scientific, methodological and
ethical standards.
Ámbito científico
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MSCA-ITN - Marie Skłodowska-Curie Innovative Training Networks (ITN)Coordinador
13284 Marseille
Francia