Project description
Embryo metabolism as a marker for IVF success
Millions of in vitro fertilisation (IVF) procedures are carried out every year, but clinical success is rather low. Selecting an embryo that will successfully implant and lead to a live birth has proved challenging. To address this problem, the EU-funded Embryospin project proposes to develop a novel method that assesses the embryo’s metabolic activity. The method is based on micro nuclear magnetic resonance (NMR), a miniaturised version of NMR instrumentation ideal for point-of-care medical diagnosis. Embryospin offers a novel biomarker for embryo vitality, which is expected to increase the chances of pregnancy, significantly reducing IVF cycles.
Objective
EmbryoSpin is a proprietary sensor for μNMR, capable to increase the sensitivity by an order of magnitude (10x) with respect to the state-of-the-art, thus allowing the analysis of cells and materials from a completely new viewpoint. Among the host of applications for this technology, the introduction of EmbryoSpin as a fast and effective embryo selection tool during In Vitro Fertilization (IVF) treatments has proven to represent a huge business opportunity. In fact, in more than 1.69 million IVF procedures performed globally each year, embryologists adopt visual inspection to select the embryo that has most chances to be successfully implanted to the uterus, often leading to long time to pregnancy due the selection of the wrong embryo and repeated fertilization cycles. With Embryospin, embryo’s metabolic activity is measured through μNMR and is used as a reliable quantitative marker of embryo’s vitality, thus increasing the chance of pregnancy after a single treatment cycle. This is valuable for women that undergoes less fertilization cycles, and to the clinics that can enhance the number of IVF performed each year. EmbryoSpin equipment and disposable μNMR sensors will serve up to 3,500 IVF treatments, generating 33 M€ of revenues by 2025.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine gynaecology reproductive medicine
- medical and health sciences clinical medicine obstetrics
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors
- medical and health sciences clinical medicine embryology
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.2.3. - INDUSTRIAL LEADERSHIP - Innovation In SMEs
MAIN PROGRAMME
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H2020-EU.3. - PRIORITY 'Societal challenges
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H2020-EU.2.1. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
SME-2 - SME instrument phase 2
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-EIC-SMEInst-2018-2020
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
1015 LAUSANNE
Switzerland
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.