Project description DEENESFRITPL Embryo metabolism as a marker for IVF success Millions of in vitro fertilisation (IVF) procedures are carried out every year, but clinical success is rather low. Selecting an embryo that will successfully implant and lead to a live birth has proved challenging. To address this problem, the EU-funded Embryospin project proposes to develop a novel method that assesses the embryo’s metabolic activity. The method is based on micro nuclear magnetic resonance (NMR), a miniaturised version of NMR instrumentation ideal for point-of-care medical diagnosis. Embryospin offers a novel biomarker for embryo vitality, which is expected to increase the chances of pregnancy, significantly reducing IVF cycles. Show the project objective Hide the project objective Objective EmbryoSpin is a proprietary sensor for μNMR, capable to increase the sensitivity by an order of magnitude (10x) with respect to the state-of-the-art, thus allowing the analysis of cells and materials from a completely new viewpoint. Among the host of applications for this technology, the introduction of EmbryoSpin as a fast and effective embryo selection tool during In Vitro Fertilization (IVF) treatments has proven to represent a huge business opportunity. In fact, in more than 1.69 million IVF procedures performed globally each year, embryologists adopt visual inspection to select the embryo that has most chances to be successfully implanted to the uterus, often leading to long time to pregnancy due the selection of the wrong embryo and repeated fertilization cycles. With Embryospin, embryo’s metabolic activity is measured through μNMR and is used as a reliable quantitative marker of embryo’s vitality, thus increasing the chance of pregnancy after a single treatment cycle. This is valuable for women that undergoes less fertilization cycles, and to the clinics that can enhance the number of IVF performed each year. EmbryoSpin equipment and disposable μNMR sensors will serve up to 3,500 IVF treatments, generating 33 M€ of revenues by 2025. Fields of science medical and health sciencesclinical medicinegynaecologyreproductive medicinemedical and health sciencesclinical medicineobstetricsengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsmedical and health sciencesclinical medicineembryology Programme(s) H2020-EU.2.3. - INDUSTRIAL LEADERSHIP - Innovation In SMEs Main Programme H2020-EU.3. - PRIORITY 'Societal challenges H2020-EU.2.1. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies Topic(s) EIC-SMEInst-2018-2020 - SME instrument Call for proposal H2020-EIC-SMEInst-2018-2020 See other projects for this call Sub call H2020-EIC-SMEInst-2018-2020-3 Funding Scheme SME - SME instrument Coordinator ANNAIDA TECHNOLOGIES SA Net EU contribution € 1 520 687,00 Address Avenue louis-ruchonnet 26 1003 Lausanne Switzerland See on map Region Schweiz/Suisse/Svizzera Région lémanique Vaud Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 651 723,00 Participants (1) Sort alphabetically Sort by Net EU contribution Expand all Collapse all Third-party Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure. HEMEX AG Switzerland Net EU contribution € 91 000,00 Address Kasernenstrasse 30 4410 Liestal See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Schweiz/Suisse/Svizzera Nordwestschweiz Basel-Landschaft Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 39 000,00
