Evaluation of the safety and efficacy of XAV-19 in patients with COVID-19-induced moderate pneumonia: study protocol for a randomized, double-blinded, placebo-controlled phase 2 (2a and 2b) trial
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Autori:
Benjamin Gaborit, Bernard Vanhove, Marie-Anne Vibet, Aurélie Le Thuaut, Karine Lacombe, Vincent Dubee, Florence Ader, Virginie Ferre, Eric Vicaut, Jéremie Orain, Morgane Le Bras, Anne Omnes, Laetitia Berly, Alexandra Jobert, Pascale Morineau-Le Houssine, Karine Botturi, Régis Josien, Laurent Flet, Nicolas Degauque, Sophie Brouard, Odile Duvaux, Alexandra Poinas, François Raffi
Pubblicato in:
Trials, Numero 22/1, 2021, ISSN 1745-6215
Editore:
BioMed Central
DOI:
10.1186/s13063-021-05132-9
XAV-19, a Swine Glyco-Humanized Polyclonal Antibody Against SARS-CoV-2 Spike Receptor-Binding Domain, Targets Multiple Epitopes and Broadly Neutralizes Variants
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Autori:
Vanhove B, Marot S, So RT, Gaborti B, Evanno G, Malet I, Lafrogne G, Mevel E, Ciron C, Royer PJ, Lheriteau E, Raffi F, Bruzzone R, Mok CKP, Duvaux O, Marcelin AG, Calver V
Pubblicato in:
Frontiers in Immunology, Numero Vol 12, 2021, ISSN 1664-3224
Editore:
Landos Biopharma Inc
DOI:
10.3389/fimmu.2021.761250
Pharmacokinetics and Safety of XAV-19, a Swine Glyco-humanized Polyclonal Anti-SARS-CoV-2 Antibody, for COVID-19-Related Moderate Pneumonia: a Randomized, Double-Blind, Placebo-Controlled, Phase IIa Study
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Autori:
Benjamin Gaborit, Eric Dailly, Bernard Vanhove, Régis Josien, Karine Lacombe, Vincent Dubee, Virginie Ferre, Sophie Brouard, Florence Ader, Marie-Anne Vibet, Aurélie Le Thuaut, Richard Danger, Laurent Flet, Anne Omnes, Laetitia Berly, Anne Chiffoleau, Alexandra Jobert, Odile Duvaux, François Raffi
Pubblicato in:
Antimicrobial Agents and Chemotherapy, Numero 65/9, 2021, ISSN 0066-4804
Editore:
American Society for Microbiology
DOI:
10.1128/aac.01237-21
High neutralizing potency of swine glyco‐humanized polyclonal antibodies against SARS‐CoV‐2
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Autori:
Bernard Vanhove, Odile Duvaux, Juliette Rousse, Pierre‐Joseph Royer, Gwénaëlle Evanno, Carine Ciron, Elsa Lheriteau, Laurent Vacher, Nadine Gervois, Romain Oger, Yannick Jacques, Sophie Conchon, Apolline Salama, Roberto Duchi, Irina Lagutina, Andrea Perota, Philippe Delahaut, Matthieu Ledure, Melody Paulus, Ray T. So, Chris Ka‐Pun Mok, Roberto Bruzzone, Marc Bouillet, Sophie Brouard, Emanuel
Pubblicato in:
European Journal of Immunology, Numero 51/6, 2021, Pagina/e 1412-1422, ISSN 0014-2980
Editore:
John Wiley & Sons Ltd.
DOI:
10.1002/eji.202049072
