Ultrafast Raman Technologies for Protein Identification and Sequencing

Project Information

ProID

Grant agreement ID: 964363

DOI

10.3030/964363

Project closed

EC signature date 22 January 2021

Start date 1 May 2021

End date 31 October 2024

Funded under

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Total cost

€ 2 988 513,75

EU contribution

€ 2 988 513,75

Coordinated by

FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
Italy

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (8)

Outreach & Engagement plan

Outreach Engagement plan

Continuous production of nanopores to support the other experiments
Report on optimized electrokinetic conditions for controlled translocations.

Report on optimized electrokinetic conditions for controlled translocations

Quality and management procedures, risk assessment

Quality and management procedures risk assessment

Experimental characterization of the SROE (first prototype)
Time resolved Raman spectra of selected peptides and data analyses with currently available nanopores and detectors
Report on in silico calculations compared with the experiments and explanation of the main physical mechanisms involved during the translocation
Quality and management procedures, risk assessment, update

Websites, patent fillings, videos etc. (1)

Project website and communication material

Demonstrators, pilots, prototypes (1)

Report on the final design and performances (SROE final prototype)

Publications

Peer reviewed articles (25)

New Horizons in Near-Zero Refractive Index Photonics and Hyperbolic Metamaterials

Author(s): Michaël Lobet; Nathaniel Kinsey; Iñigo Liberal; Humeyra Caglayan; Paloma A. Huidobro; Emanuele Galiffi; Jorge Ricardo Mejía-Salazar; Giovanna Palermo; Zubin Jacob; Nicolò Maccaferri
Published in: Lobet , M , Kinsey , N , Liberal , I , Caglayan , H , Huidobro , P A , Galiffi , E , Mejía-Salazar , J R , Palermo , G , Jacob , Z & Maccaferri , N 2023 , ' New Horizons in Near-Zero Refractive Index Photonics and Hyperbolic Metamaterials ' , ACS Photonics , vol. 10 , no. 11 , pp. 3805-3820 . https://doi.org/10.1021/acsphotonics.3c00747, Issue 10, 11, 2023, Page(s) 3805–3820, ISSN 2330-4022
Publisher: American Chemical Society
DOI: 10.1021/acsphotonics.3c00747

Enhanced Optical Spectroscopy for Multiplexed DNA and Protein-Sequencing with Plasmonic Nanopores: Challenges and Prospects

Author(s): Wang Li, Juan Zhou, Nicolò Maccaferri, Roman Krahne, Kang Wang*, and Denis Garoli*
Published in: Analytical Chemistry, Issue 94, 2, 2022, Page(s) 503–514, ISSN 0003-2700
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.1c04459

Plasmonic Bowl-Shaped Nanopore for Raman Detection of Single DNA Molecules in Flow-Through

Author(s): Yingqi Zhao, Aliaksandr Hubarevich, Angela Federica De Fazio, Marzia Iarossi, Jian-An Huang, and Francesco De Angelis
Published in: Nano Letters, Issue 23, 11, 2023, Page(s) 4830–4836, ISSN 1530-6984
Publisher: American Chemical Society
DOI: 10.1021/acs.nanolett.3c00340

Single Photon Avalanche Diode Arrays for Time-Resolved Raman Spectroscopy

Author(s): Francesca Madonini; Federica Villa
Published in: Sensors (Basel, Switzerland), Issue Vol. 21, 2021, Page(s) 4287, ISSN 1424-8220
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/s21134287

Sub-picosecond collapse of molecular polaritons to pure molecular transition in plasmonic photoswitch-nanoantennas

Author(s): Joel Kuttruff; Marco Romanelli; Esteban Pedrueza-Villalmanzo; Jonas Allerbeck; Jacopo Fregoni; Valeria Saavedra-Becerril; Joakim Andréasson; Daniele Brida; Alexandre Dmitriev; Stefano Corni; Nicolò Maccaferri
Published in: Nature Communications, Issue Vol 14, Iss 1, Pp 1-10 (2023), 2023, Page(s) 3875, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-39413-5

Advances in ultrafast plasmonics

Author(s): Alemayehu Nana Koya; Marco Romanelli; Joel Kuttruff; Nils Henriksson; Andrei Stefancu; Gustavo Grinblat; Aitor De Andres; Fritz Schnur; Mirko Vanzan; Margherita Marsili; Mahfujur Rahaman; Alba Viejo Rodríguez; Tlek Tapani; Haifeng Lin; Bereket Dalga Dana; Jingquan Lin; Grégory Barbillon; Remo Proietti Zaccaria; Daniele Brida; Deep Jariwala; László Veisz; Emiliano Cortés; Stefano Corni; Denis
Published in: Applied physics reviews 10 (2023). doi:10.1063/5.0134993, Issue 10, 021318, 2023, ISSN 1931-9401
Publisher: AIP Publishing LLC
DOI: 10.1063/5.0134993

Inverse design of molecule–metal nanoparticle systems interacting with light for desired photophysical properties

Author(s): Takafumi Shiraogawa; Giulia Dall’Osto; Roberto Cammi; Masahiro Ehara; Stefano Corni
Published in: Physical Chemistry Chemical Physics, Issue 24, 2022, Page(s) 22768-22777, ISSN 1463-9076
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2cp02870k

On Iterative Pre‐Compensation of 3D Laser‐Printed Micro‐Optical Components Using Confocal‐Optical Microscopy

Author(s): Jannis Weinacker, Sebastian Kalt, Pascal Kiefer, Pascal Rietz, Martin Wegener
Published in: Advanced Functional Materials, Issue 34, 2024, ISSN 1616-301X
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202309356

Ultrafast Thermionic Electron Injection Effects on Exciton Formation Dynamics at a van der Waals Semiconductor/Metal Interface

Author(s): Kilian R. Keller, Ricardo Rojas-Aedo, Huiqin Zhang, Pirmin Schweizer, Jonas Allerbeck, Daniele Brida, Deep Jariwala, and Nicolò Maccaferri*
Published in: ACS Photonics, Issue 9, 8, 2022, Page(s) 2683–2690, ISSN 2330-4022
Publisher: American Chemical Society
DOI: 10.1021/acsphotonics.2c00394

A generalized protein identification method for novel and diverse sequencing technologies

Author(s): Bikash Kumar Bhandari, Nick Goldman
Published in: NAR Genomics and Bioinformatics, Issue 6, 2024, ISSN 2631-9268
Publisher: Oxford University Press
DOI: 10.1093/nargab/lqae126

Unraveling the electronic origin of a special feature in the triplet-minus-singlet spectra of carotenoids in natural photosystems

Author(s): Agostino Migliore; Stefano Corni; Alessandro Agostini; Donatella Carbonera
Published in: Phys. Chem. Chem. Phys., Issue 25, 2023, Page(s) 28998-29016, ISSN 1463-9084
Publisher: Royal Society of Chemistry
DOI: 10.1039/d3cp03836j

Unraveling the Mechanism of Tip-Enhanced Molecular Energy Transfer

Author(s): Coane, Colin; Romanelli, Marco; Dall'Osto, Giulia; Di Felice, Rosa; Corni, Stefano
Published in: Communications Chemistry, Issue 32, 2024, ISSN 2399-3669
Publisher: Stringer Nature
DOI: 10.48550/arxiv.2305.17265

Magnetoplasmonics in confined geometries: Current challenges and future opportunities

Author(s): Nicolò Maccaferri; Alessio Gabbani; Francesco Pineider; Terunori Kaihara; Tlek Tapani; Paolo Vavassori
Published in: Applied Physics Letters, Issue 122, 2023, Page(s) 120502, ISSN 0003-6951
Publisher: American Institute of Physics
DOI: 10.1063/5.0136941

QM/Classical Modeling of Surface Enhanced Raman Scattering Based on Atomistic Electromagnetic Models

Author(s): Piero Lafiosca, Luca Nicoli, Luca Bonatti, Tommaso Giovannini, Stefano Corni, Chiara Cappelli
Published in: Journal of Chemical Theory and Computation, Issue 19, 2023, Page(s) 3616-3633, ISSN 1549-9618
Publisher: American Chemical Society
DOI: 10.1021/acs.jctc.3c00177

The 2022 magneto-optics roadmap

Author(s): Alexey Kimel, Anatoly Zvezdin, Sangeeta Sharma, Samuel Shallcross, Nuno de Sousa, Antonio García-Martín, Georgeta Salvan, Jaroslav Hamrle, Ondřej Stejskal, Jeffrey McCord, Silvia Tacchi, Giovanni Carlotti, Pietro Gambardella, Gian Salis, Markus Münzenberg, Martin Schultze, Vasily Temnov, Igor V Bychkov, Leonid N Kotov, Nicolò Maccaferri, Daria Ignatyeva, Vladimir Belotelov, Claire Donnelly, A
Published in: Journal of Physics D: Applied Physics, Issue Volume 55, Number 46, 2022, Page(s) 463003, ISSN 0022-3727
Publisher: Institute of Physics Publishing
DOI: 10.1088/1361-6463/ac8da0

Do We Really Need Quantum Mechanics to Describe Plasmonic Properties of Metal Nanostructures?

Author(s): Giovannini, Tommaso; Bonatti, Luca; Lafiosca, Piero; Nicoli, Luca; Castagnola, Matteo; Grobas Illobre, Pablo; Corni, Stefano; Cappelli, Chiara
Published in: ACS Photonics, Issue 23304022, 2022, Page(s) 3025–3034, ISSN 2330-4022
Publisher: American Chemical Society
DOI: 10.1021/acsphotonics.2c00761

Label-Free Optical Analysis of Biomolecules in Solid-State Nanopores: Toward Single-Molecule Protein Sequencing

Author(s): Yingqi Zhao; Marzia Iarossi; Angela Federica De Fazio; Jian-An Huang; Francesco De Angelis
Published in: ACS Photonics, Issue 9, 3, 2022, Page(s) 730–742, ISSN 2330-4022
Publisher: American Chemical Society
DOI: 10.1021/acsphotonics.1c01825

Magnetic control of particle trapping in a hybrid plasmonic nanopore

Author(s): Nicolò Maccaferri, Paolo Vavassori, and Denis Garoli
Published in: Applied Physics Letters, Issue 118, 2021, Page(s) 193102, ISSN 0003-6951
Publisher: American Institute of Physics
DOI: 10.1063/5.0046245

Time-dependent surface-enhanced Raman scattering: A theoretical approach

Author(s): Giulia Dall’Osto, Stefano Corni
Published in: The Journal of Chemical Physics, Issue 161, 2024, ISSN 0021-9606
Publisher: American Institute of Physics
DOI: 10.1063/5.0214564

Atomistic Simulations of Functionalized Nano-Materials for Biosensors Applications

Author(s): Sutapa Dutta; Stefano Corni; Giorgia Brancolini
Published in: International Journal of Molecular Sciences, Issue Vol. 23, 2022, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23031484

Magnetophotonics for sensing and magnetometry toward industrial applications

Author(s): Conrad Rizal; Maria Grazia Manera; Daria O. Ignatyeva; Jorge R. Mejía-Salazar; Roberto Rella; Vladimir I. Belotelov; Francesco Pineider; Nicolò Maccaferri
Published in: Journal of Applied Physics, Issue 130, 2021, Page(s) 230901, ISSN 0021-8979
Publisher: American Institute of Physics
DOI: 10.1063/5.0072884

Real-Time Formulation of Atomistic Electromagnetic Models for Plasmonics

Author(s): Piero Lafiosca, Luca Nicoli, Silvio Pipolo, Stefano Corni, Tommaso Giovannini, Chiara Cappelli
Published in: The Journal of Physical Chemistry C, Issue 128, 2024, Page(s) 17513-17525, ISSN 1932-7447
Publisher: American Chemical Society
DOI: 10.1021/acs.jpcc.4c04002

Plasmonic Photochemistry as a Tool to Prepare Metallic Nanopores with Controlled Diameter for Optimized Detection of Single Entities

Author(s): Lanzavecchia, German; Kuttruff, Joel; Doricchi, Andrea; Douaki, Ali; Kumaranchira Ramankutty, Krishnadas; García, Isabel; Lin, Lyuye; Viejo Rodríguez, Alba; Wågberg, Thomas; Krahne, Roman; Maccaferri, Nicolò; Garoli, Denis
Published in: Advanced Optical Materials, Issue 11, 16, 2023, Page(s) 2300786, ISSN 2195-1071
Publisher: Wiley
DOI: 10.1002/adom.202300786

Magneto-Optical Activity in Nonmagnetic Hyperbolic Nanoparticles

Author(s): Joel Kuttruff, Alessio Gabbani, Gaia Petrucci, Yingqi Zhao, Marzia Iarossi, Esteban Pedrueza-Villalmanzo, Alexandre Dmitriev, Antonietta Parracino, Giuseppe Strangi, Francesco De Angelis, Daniele Brida, Francesco Pineider, and Nicolò Maccaferri
Published in: PHYSICAL REVIEW LETTERS, Issue 127, 2021, Page(s) 217402, ISSN 0031-9007
Publisher: American Physical Society
DOI: 10.1103/physrevlett.127.217402

Role of Ionic Strength in the Formation of Stable Supramolecular Nanoparticle–Protein Conjugates for Biosensing

Author(s): Giorgia Brancolini; Vincent Rotello; Stefano Corni
Published in: International Journal of Molecular Sciences, Issue Vol. 23, 2022, Page(s) 2368, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23042368

Conference proceedings (4)

SPAD Sensors for Time-Gated Raman Spectroscopy

Author(s): Francesca Madonini, Arianna Adelaide Maurina, and Federica Villa
Published in: Microscopy Histopathology and Analytics 2022, 2022, ISBN 978-1-957171-03-6
Publisher: Optica Publishing Group
DOI: 10.1364/translational.2022.jm3a.13

Ultrafast Dynamics of Photochromic Molecules Coupled to Anisotropic Plasmon Nanoantennas

Author(s): Joel Kuttruff, Marco Romanelli, Esteban Pedrueza-Villalmanzo, Jonas Allerbeck, Jacopo Fregoni, Valeria Saavedra-Becerril, Joakim Andreasson, Daniele Brida, Alexandre Dmitriev, Stefano Corni, and Nicolò Maccaferri
Published in: CLEO: QELS_Fundamental Science 2022, 2022, ISBN 978-1-957171-05-0
Publisher: Optica Publishing Group
DOI: 10.1364/cleo_qels.2022.fm2a.2

Sub-ps Thermionic Charge Injection Effect on Exciton Formation Dynamics at Tungsten disulfide (WS2)/Metal Schottky Junction

Author(s): R. Rojas-Aedo, K. R. Keller, H. Zhang, P. Schweizer, J. Allerbeck, D. Brida, D. Jariwala, and N. Maccaferri
Published in: CLEO: Applications and Technology 2022, 2022, ISBN 978-1-957171-05-0
Publisher: Optica Publishing Group
DOI: 10.1364/cleo_at.2022.jtu3a.30

Control of particle trapping in solid-state nanopores with magnetic functionalities: an overview

Author(s): Alemayehu Nana Koya, Joel Kuttruff, Tilaike Tapani, Alba Viejo Rodríguez, Sreyash Sarkar, Ornella Vaccarelli, Nicolò Maccaferri
Published in: Proceedings Volume 12131, Nanophotonics IX, 2022
Publisher: SPIE
DOI: 10.1117/12.2622218