DNA-Fast light dRiven data technologY with multiplexed optical encoding and readout

Project Information

DNA-FAIRYLIGHTS

Grant agreement ID: 964995

DOI

10.3030/964995

Project closed

EC signature date 22 January 2021

Start date 1 September 2021

End date 28 February 2025

Funded under

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Total cost

€ 3 116 536,25

EU contribution

€ 3 116 536,25

Coordinated by

FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
Italy

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Demonstrators, pilots, prototypes (2)

Scale up model.
Electro-optical read out of high density data structures with nanopores and optical detection

Documents, reports (3)

Characterization and evaluation of dynamic control of NPs and NCs positons and orientations.
Report on project communication n.1

Report on project communication n 1

Report on project communication n. 2

Websites, patent fillings, videos etc. (1)

Project WebSite and Logo

realization and publication online of the project website

Publications

Peer reviewed articles (28)

DNA Volume, Topology, and Flexibility Dictate Nanopore Current Signals

Author(s): Yunxuan Li, Sarah E. Sandler, Ulrich F. Keyser, Jinbo Zhu
Published in: Nano Letters, Issue 23, 2023, Page(s) 7054-7061, ISSN 1530-6984
Publisher: American Chemical Society
DOI: 10.1021/acs.nanolett.3c01823

Magnetic control of particle trapping in a hybrid plasmonic nanopore

Author(s): Nicolo Maccaferri, Paolo Vavassori, and Denis Garoli
Published in: Applied physics letters, 2021, ISSN 0003-6951
Publisher: American Institute of Physics
DOI: 10.1063/5.0046245

Aptamer Conformational Dynamics Modulate Neurotransmitter Sensing in Nanopores

Author(s): Annina Stuber, Ali Douaki, Julian Hengsteler, Denis Buckingham, Dmitry Momotenko, Denis Garoli, and Nako Nakatsuka
Published in: ACS Nano, 2023, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.3c05377

Dynamics of ultrafine silver implanted DNA nanowire formation

Author(s): Qifei Ma, Mauro Chinappi, Ali Douaki, Yanqiu Zou, Huaizhou Jin, Emiliano Descrovi, Roman Krahne, Remo Proietti Zaccaria, Roberto Marotta, Weihong Wang, Dan Cojoc, Karol kołątaj, Guillermo Acuna, Shangzhong Jin, Denis Garoli
Published in: Nanoscale, Issue 17, 2025, Page(s) 16342-16348, ISSN 2040-3364
Publisher: Royal Society of Chemistry
DOI: 10.1039/d5nr00934k

Nanopore detection of single-nucleotide RNA mutations and modifications with programmable nanolatches

Author(s): Yunxuan Li, Siong Chen Meng, Yesheng Wang, Casey M. Platnich, Max K. Earle, Elli Mylona, Plamena Naydenova, Stephen Baker, Jinbo Zhu, Ulrich F. Keyser
Published in: Nature Nanotechnology, 2025, ISSN 1748-3387
Publisher: Nature Publishing Group
DOI: 10.1038/s41565-025-01965-6

Modulating Lipid Membrane Morphology by Dynamic DNA Origami Networks

Author(s): Juanjuan Yang, Kevin Jahnke, Ling Xin, Xinxin Jing, Pengfei Zhan, Andreas Peil, Alessandra Griffo, Marko Škugor, Donglei Yang, Sisi Fan, Kerstin Göpfrich, Hao Yan, Pengfei Wang, Na Liu
Published in: Nano Letters, Issue 23, 2023, Page(s) 6330-6336, ISSN 1530-6984
Publisher: American Chemical Society
DOI: 10.1021/acs.nanolett.3c00750

Detection of protein oligomers with nanopores 

Author(s): Robert I. Horne, Sarah E. Sandler, Michele Vendruscolo, Ulrich F. Keyser
Published in: Nature Reviews Chemistry, Issue 9, 2025, Page(s) 224-240, ISSN 2397-3358
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s41570-025-00694-7

Dry synthesis of bi-layer nanoporous metal films as plasmonic metamaterial

Author(s): Vincenzo Caligiuri, Hyunah Kwon, Andrea Griesi, Yurii P. Ivanov, Andrea Schirato, Alessandro Alabastri, Massimo Cuscunà, Gianluca Balestra, Antonio De Luca, Tlek Tapani, Haifeng Lin, Nicolò Maccaferri, Roman Krahne, Giorgio Divitini, Peer Fischer, Denis Garoli
Published in: Nanophotonics, Issue 13, 2024, Page(s) 1159-1167, ISSN 2192-8614
Publisher: Walter de Gruyter GmbH
DOI: 10.1515/nanoph-2023-0942

Detection of small-sized DNA fragments in a glassy nanopore by utilization of CRISPR-Cas12a as a converter system

Author(s): Shumin Zhang, Minyi Liu, Haofa Cui, Muhammad Asad Ziaee, Rongwei Sun, Liting Chen, Daqi Chen, Denis Garoli and Jiahai Wang
Published in: Analyst, Issue 13645528, 2022, ISSN 1364-5528
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1an02313f

Biomolecular ligands as tools to modulate the optical and chiroptical properties of gold nanoclusters

Author(s): Laura Saa, Manuel Núñez-Martínez, Eva Carpintero-Cueto, Aitziber L. Cortajarena
Published in: Nanoscale, Issue 17, 2025, Page(s) 3671-3687, ISSN 2040-3364
Publisher: Royal Society of Chemistry
DOI: 10.1039/d4nr04267k

Plasmonic Photochemistry as a Tool to Prepare Metallic Nanopores with Controlled Diameter for Optimized Detection of Single Entities

Author(s): German Lanzavecchia, Joel Kuttruff, Andrea Doricchi, Ali Douaki, Krishnadas Kumaranchira Ramankutty, Isabel García, Lyuye Lin, Alba Viejo Rodríguez, Thomas Wågberg, Roman Krahne, Nicolò Maccaferri, Denis Garoli
Published in: Advanced Optical Materials, 2023, Page(s) 2300786, ISSN 2195-1071
Publisher: Wyley
DOI: 10.1002/adom.202300786

Chiroptical hybrid nanomaterials based on metal nanoparticles and biomolecules

Author(s): Manuel Núñez-Martínez, Jinyi Dong, Isabel García, Luis M. Liz-Marzán
Published in: Advances in Colloid and Interface Science, Issue 341, 2025, Page(s) 103501, ISSN 0001-8686
Publisher: Elsevier BV
DOI: 10.1016/j.cis.2025.103501

Disordered plasmonic system with dense copper nano-island morphology

Author(s): Tlek Tapani, Vincenzo Caligiuri, Yanqiu Zou, Andrea Griesi, Yurii P. Ivanov, Massimo Cuscunà, Gianluca Balestra, Haifeng Lin, Anastasiia Sapunova, Paolo Franceschini, Andrea Tognazzi, Costantino De Angelis, Giorgio Divitini, Riccardo Carzino, Hyunah Kwon, Peer Fischer, Roman Krahne, Nicolò Maccaferri, Denis Garoli
Published in: Nanophotonics, Issue 14, 2025, Page(s) 2151-2160, ISSN 2192-8614
Publisher: Walter de Gruyter GmbH
DOI: 10.1515/nanoph-2024-0743

Universal Click-Chemistry Approach for the DNA Functionalization of Nanoparticles

Author(s): Nicole Siegel, Hiroaki Hasebe, Germán Chiarelli, Denis Garoli, Hiroshi Sugimoto, Minoru Fujii, Guillermo P. Acuna, Karol Kołątaj
Published in: Journal of the American Chemical Society, Issue 146, 2024, Page(s) 17250-17260, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.4c03833

High-Frequency Light Rectification by Nanoscale Plasmonic Conical Antenna in Point-Contact-Insulator-Metal Architecture

Author(s): Rajeshkumar Mupparapu,Joao Cunha,Francesco Tantussi,Andrea Jacassi,Leopold Summerer,Maddalena Patrini,Andrea Giugni,Lorenzo Maserati,Alessandro Alabastri,Denis Garoli,Remo Proietti Zaccaria
Published in: Advanced energy materials, 2022, ISSN 1614-6840
Publisher: Wiley
DOI: 10.1002/aenm.202103785

Chemical annealing restructures RNA for nanopore detection

Author(s): Casey Platnich, Max Earle, Ulrich Keyser
Published in: Journal of the american chemical society, 2024, ISSN 1520-5126
Publisher: American chemical society
DOI: 10.26434/chemrxiv-2024-2pm9p

A digital twin for DNA data storage based on comprehensive quantification of errors and biases

Author(s): Andreas L. Gimpel, Wendelin J. Stark, Reinhard Heckel & Robert N. Grass
Published in: Nature Communications, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-41729-1

Enhanced Optical Spectroscopy for Multiplexed DNA and Protein-Sequencing with Plasmonic Nanopores: Challenges and Prospects

Author(s): Wang Li, Juan Zhou, Nicolò Maccaferri, Roman Krahne, Kang Wang, and Denis Garoli
Published in: Analytical Chemistry, 2022, ISSN 1520-6882
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.1c04459

Emerging Approaches to DNA Data Storage: Challenges and Prospects

Author(s): Andrea Doricchi, Casey M. Platnich, Andreas Gimpel, Friederikee Horn, Max Earle, German Lanzavecchia, Aitziber L. Cortajarena, Luis M. Liz-Marzán, Na Liu, Reinhard Heckel, Robert N. Grass, Roman Krahne, Ulrich F. Keyser, and Denis Garoli
Published in: ACS Nano, Issue 16, 2022, ISSN 1936-086X
Publisher: Americal Chemical Society
DOI: 10.1021/acsnano.2c06748

Transformable Plasmonic Helix with Swinging Gold Nanoparticles

Author(s): Andreas Peil, Dr. Pengfei Zhan, Dr. Xiaoyang Duan, Prof. Roman Krahne, Dr. Denis Garoli, Prof. Dr. Luis M. Liz-Marzán, Prof. Dr. Na Liu
Published in: Angewandte Chemie, 2022, ISSN 1521-3773
Publisher: wyley
DOI: 10.1002/anie.202213992

Nanoporous Metals: From Plasmonic Properties to Applications in Enhanced Spectroscopy and Photocatalysis

Author(s): Alemayehu Nana Koya, Xiangchao Zhu, Nareg Ohannesian, A. Ali Yanik, Alessandro Alabastri, Remo Proietti Zaccaria, Roman Krahne, Wei-Chuan Shih, and Denis Garoli
Published in: ACS Nano, Issue 15, 2021, Page(s) 6038–6060, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.0c10945

Chemical unclonable functions based on operable random DNA pools

Author(s): Anne M. Luescher, Andreas L. Gimpel, Wendelin J. Stark, Reinhard Heckel, Robert N. Grass
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-47187-7

Recent Advances in DNA Origami-Engineered Nanomaterials and Applications

Author(s): Pengfei Zhan, Andreas Peil, Qiao Jiang, Dongfang Wang, Shikufa Mousavi, Qiancheng Xiong, Qi Shen, Yingxu Shang, Baoquan Ding, Chenxiang Lin, Yonggang Ke, Na Liu
Published in: Chemical Reviews, Issue 123, 2023, Page(s) 3976-4050, ISSN 0009-2665
Publisher: American Chemical Society
DOI: 10.1021/acs.chemrev.3c00028

Modular Plasmonic Nanopore for Opto‐Thermal Gating

Author(s): Ali Douaki, Shukun Weng, German Lanzavecchia, Anastasiia Sapunova, Annina Stuber, Gabriele Nanni, Nako Nakatsuka, Makusu Tsutsui, Kazumichi Yokota, Roman Krahne, Denis Garoli
Published in: Advanced Optical Materials, Issue 13, 2025, ISSN 2195-1071
Publisher: Wiley
DOI: 10.1002/adom.202402189

UV-SERS monitoring of plasmonic photodegradation of biomolecules on aluminum platforms decorated with rhodium nanoparticles

Author(s): Yanqiu Zou, Luca Mattarozzi, Huaizhou Jin, Qifei Ma, Sandro Cattarin, Shukun Weng, Ali Douaki, German Lanzavecchia, Karol Kołątaj, Nicco Corduri, Ben Johns, Nicolò Maccaferri, Guillermo Acuna, Zhenrong Zheng, Shangzhong Jin, Denis Garoli
Published in: Nanoscale Advances, 2025, ISSN 2516-0230
Publisher: Royal Society of Chemistry (RSC)
DOI: 10.1039/d5na00486a

Advances in ultrafast plasmonics

Author(s): Alemayehu Nana Koya ; Marco Romanelli ; Joel Kuttruff; Nils Henriksson ; Andrei Stefancu ; Gustavo Grinblat ; Aitor De Andres ; Fritz Schnur ; Mirko Vanzan ; Margherita Marsili ; Mahfujur Rahaman ; Alba Viejo Rodríguez ; Tlek Tapani ; Haifeng Lin ; Bereket Dalga Dana ; Jingquan Lin ; Grégory Barbillon ; Remo Proietti Zaccaria ; Daniele Brida ; Deep Jariwala ; László Veisz ; Emiliano Cor
Published in: Applied Physics Review, 2023, ISSN 1931-9401
Publisher: AIP Publishing LLC
DOI: 10.1063/5.0134993

Porous aluminum decorated with rhodium nanoparticles: preparation and use as a platform for UV SERS

Author(s): Shrobona Banerjee, Luca Mattarozzi, Nicolò Maccaferri, Sandro Cattarin, Shukun Weng, Ali Douaki, German Lanzavecchia, Anastasiia Sapunova, Francesco D'Amico, Qifei Ma, Yanqiu Zou, Roman Krahne, Janina Kneipp, Denis Garoli
Published in: Materials Advances, Issue 5, 2024, Page(s) 6248-6254, ISSN 2633-5409
Publisher: Royal Society of Chemistry (RSC)
DOI: 10.1039/d4ma00203b

Challenges for error-correction coding in DNA data storage: photolithographic synthesis and DNA decay

Author(s): Andreas L. Gimpel, Wendelin J. Stark, Reinhard Heckel, Robert N. Grass
Published in: Digital Discovery, Issue 3, 2024, Page(s) 2497-2508, ISSN 2635-098X
Publisher: Royal Society of Chemistry (RSC)
DOI: 10.1039/d4dd00220b

Non-peer reviewed articles (3)

Nanopore detection of modified RNA and DNA with nucleic acid catalyst-free click chemistry

Author(s): Iva Mohora, Gerardo Patiño Guillén, Kevin Neis, Julián Valero, Ulrich Keyser, Filip Boskovic
Published in: chemxiv, 2024, ISSN 0000-0000
Publisher: chemrxiv
DOI: 10.26434/chemrxiv-2024-swxn6

Single-Molecule Quantification of RNA Degradation with Nanopore Sensing

Author(s): Mohammed Alawami, Max Earle, Ulrich Keyser, Casey Platnich
Published in: Chemrxiv, 2025, ISSN 0000-0000
Publisher: chemrxiv
DOI: 10.26434/chemrxiv-2025-th9vf

Corrigendum to “Chiroptical hybrid nanomaterials based on metal nanoparticles and biomolecules” [Adv. Colloid Interface Sci. 341 (2025) 103501]

Author(s): Manuel Núñez-Martínez, Jinyi Dong, Isabel García, Luis M. Liz-Marzán
Published in: Advances in Colloid and Interface Science, Issue 342, 2025, Page(s) 103560, ISSN 0001-8686
Publisher: Elsevier BV
DOI: 10.1016/j.cis.2025.103560