Resultado final
Data Management Plan generated for Pilot on Open Research Data from Task 11Health actions that participates in the ORDPThe Data Management Plan will be generated within 6 months after the project starts for participating in the H2020 Pilot on Open Research Data This plan will be included in the Project Management Plan which will be updated yearly
First publication of SLEEP REVOLUTION project in JSR or other scientific journal as deemed appropriate from Task 121The ESRS publishes one of the principle international scientific journals the Journal of Sleep Research JSR which with an impact factor of 34 is in the top 3 international scientific sleep journals publishing original research
First dissemination of findings from SLEEP REVOLUTION project.First dissemination of findings from SLEEP REVOLUTION project from Task 122OSA is a multisystem disorder that has important cardiometabolic comorbidities which are often not well recognised by health professionals and patients within these disciplines ESRS will play a central role in dissemination of relevant findings from SLEEP REVOLUTION to professional organizations with many sleep apnoea patients cardiology neurology respiratory diabetes obesity within Europe to patient organizations as well as to European societies Such dissemination is facilitated by established intersociety links with other European Societies such as the European Society of Hypertension the ERS and the European Academy of Neurology that have already resulted in the publication of joint position papers on the association of sleep apnoea with important comorbidities such as hypertension 64 and stroke 65 A website for the SLEEP REVOLUTION project will also be setup and linked to the the wwwesrseu website
First project presentation at the ESRS Scientific Congresses.First project presentation at the ESRS Scientific Congresses from Task 121The ESRS holds annual conferences relating to sleep research and medicine The biannual ESRS Congress is the premier scientific congress in Europe relating to sleep research The Sleep and Breathing Congress is a biannual conference held jointly with ERS that is especially focused on education and continuing professional development These events provide the optimum opportunity to present original data arising from research performed in the various WPs of SLEEP REVOLUTION
Translation to different languagesTranslation to different languages from Task 74All applicable text and functions in the DMP as seen by healthcare professionals and research staff will be in English A part of the development strategy of the DMP will make the text easily translated to other languages The translation aspect will therefore be included from the start and translating the DMP to a new language will include the manual labour of working with structured files However for the research subjectpatient relevant text and functions in the DMP will need to be translated into the respective language of different countries participating in WP810 This includes the PROMs in the European Sleep Questionnaire and electronic sleep diary NEH which require translation with the assistance of experienced translators The visualizations of data from the wearables will need some translations for each country which this task will also cover If needed text and functions in relation to the mobile application program by SKH objective daytime testing wearables Withings and ES sleep studies NOX and overall platform will also be translated This may however not be needed in all countries depending on the English proficiency of the population eg not needed in Iceland and we will assess which languages are needed as a part of this task
Deep learning algorithm for automatic estimation of sleep microstructure.Deep learning algorithm for automatic estimation of sleep microstructure from Task 32This deliverable includes the followingTo validate the stateoftheart deep learning methodologies currently being developed for automatic sleep staging by our team The detailed deep learningbased analysis will allow the assessment of a time series analysis of the continuity of sleep microstructure instead of sleep fragmentation definitions based on arbitrary and discrete 30 seconds epochs Finally novel arousal detection will be incorporated into the sleep staging and the effect of arousal length and magnitude to patients wellbeing will be investigated
Respiratory event quantification by an expanded number of potentially important clinical parameters.Respiratory event quantification by an expanded number of potentially important clinical parameters from Task 31The deliverable includes the following quantificationTo quantify respiratory events A by different physiological parameters This includes parameters such as the traditional AHI apnoea and hypopnea length the individual role of apnoeas vs hypopneas snore percentage and duration of total sleep snore loudness flow limitation and breathing effort Different physiological parameters will be assessed to find the most clinically relevant methods of quantifying A
Recommendations for most relevant and information-rich signals to be measured in sleep studies.Recommendations for most relevant and informationrich signals to be measured in sleep studies from Task 53Using the sophisticated deep neural networks for an accurate SDB diagnosis and severity assessment will guide us to select the most informationrich signals and determine the minimum sensor and sampling setups needed This is critically important to optimise the diagnostic sensitivity minimum sensor setup maximal patient comfort and automation of data processing and analysis This information will be used for the final design of the SAS system in WP6 and included in the stateoftheart scoring manual created in WP4 D44
Real-world estimates of long-term costs of OSARealworld estimates of longterm costs of OSA from Task 111This deliverable is to collect relevant data on longterm costs of SDB and OSA using the retrospective data collected in WP3 This data will be utilized to select the most relevant measures and outcomes As the outcomesmeasures are not specific to SDB alone SDBrelated contribution will be extracted by using population attributable factors based on the known prevalence of diseases and increased risks related to SDB and OSA Here the analysed datasets will include at least 1 a longitudinal Kuopio Osteoporosis Risk Factor and Prevention Study OSTPREstudy on more than 14000 aging females followed since 1989 with questionnaires health investigations and registerbased followup and 2 a registerbased Diabetes in Finland FinDMresearch dataset of about one million persons with diagnosed diabetes since 1964
Comparison of unsupervised and supervised learning outcomes for SDB-related co-morbidities.Comparison of unsupervised and supervised learning outcomes for SDBrelated comorbidities from Task 52Here we will to use backpropagation to pinpoint the most relevant signal features utilised by the machine learning approach when predicting the probabilities for OSArelated comorbidities and compare unsupervised to supervised machine learning techniques
Reliability report on automatic and manual scorings.Reliability report on automatic and manual scorings from Task 42The agreement between the automatic analysis approach D41 and manual scorers D42 will be evaluated and submitted in a report
Acute systemic effect quantification by an expanded number of potentially important clinical parameters.Acute systemic effect quantification by an expanded number of potentially important clinical parameters from Task 33The deliverable includes the followingTo expand the selection of parameters for pulse oximetry and ECG data for evaluating the risk of the most common OSArelated comorbidities such as cardiovascular diseases cerebrovascular diseases and metabolic disorders
Establishment of an ethical guardian at each study site from Task 13.2.Due to the complexity of the network involved in this study, an ethical guardian will be appointed to co-ordinate ethical approval application processes in each of the institutions and countries involved in the data collection.
Establishment of the External Ethics Advisory BoardEstablishment of the External Ethics Advisory Board from Task 13.2.a one-person EEAB will be established at the beginning of the project and maintained until the end of the project.
Publicaciones
Autores:
Dirk Pevernagie
Publicado en:
Sleep Medicine Clinics, Edición vol 16 (3), 2021, Página(s) 465-473, ISSN 1556-407X
Editor:
Elsevier BV
DOI:
10.1016/j.jsmc.2021.05.005
Autores:
Purbanka Pahari, Henri Korkalainen, Tuomas Karhu, Marika Rissanen, Erna Sif Arnardottir, Harald Hrubos-Strøm, Brett Duce, Juha Töyräs, Timo Leppänen, Sami Nikkonen
Publicado en:
Journal of Sleep Research, 2022, ISSN 1613-6810
Editor:
Wiley - V C H Verlag GmbbH & Co.
DOI:
10.1111/jsr.13803
Autores:
T. Leppänen, C. Varon, M.d. Zambotti, and S. Myllymaa
Publicado en:
Front. Digit. Health, 2022, 4:845879, Edición 2673253X, 2022, ISSN 2673-253X
Editor:
Frontiers in digital health
DOI:
10.3389/fdgth.2022.845879
Autores:
Hlín Kristbergsdottir; Lisa Schmitz; Erna Sif Arnardottir; Anna Sigridur Islind
Publicado en:
Diagnostics, Vol 13, Iss 18, p 2883 (2023), Edición 5, 2023, ISSN 2075-4418
Editor:
Basel: MDPI AG
DOI:
10.3390/diagnostics13182883
Autores:
M. Rusanen, S. Myllymaa, L. Kalevo, K. Myllymaa, J. Töyräs, T. Leppänen, and S. Kainulainen
Publicado en:
IEEE Access, 2021, 9:132580-132591, Edición 21693536, 2021, ISSN 2169-3536
Editor:
Institute of Electrical and Electronics Engineers Inc.
DOI:
10.1109/access.2021.3113049
Autores:
LAURA KALEVO, TOMI MIETTINEN, AKSELI LEINO, SUSANNA WESTEREN-PUNNONEN, JOHANNA SAHLMAN, ESA MERVAALA, JUHA TÖYRÄS, TIMO LEPPÄNEN, SAMI MYLLYMAA, KATJA MYLLYMAA
Publicado en:
IEEE Access, Edición vol 10, 2022, Página(s) 60633-60642, ISSN 2169-3536
Editor:
Institute of Electrical and Electronics Engineers Inc.
DOI:
10.1109/access.2022.3178189
Autores:
Akseli Leino; Henri Korkalainen; Laura Kalevo; Sami Nikkonen; Samu Kainulainen; Alexander Ryan; Brett Duce; Kirsi Sipila; Jari Ahlberg; Johanna Sahlman; Tomi Miettinen; Susanna Westeren-Punnonen; Esa Mervaala; Juha Toyras; Sami Myllymaa; Timo Leppanen; Katja Myllymaa
Publicado en:
IEEE Access, Edición Vol 10, 2022, Página(s) 26554 - 26566, ISSN 2169-3536
Editor:
Institute of Electrical and Electronics Engineers Inc.
DOI:
10.1109/access.2022.3154899
Autores:
Tuomas Karhu, Timo Leppänen, Juha Töyräs, Arie Oksenberg, Sami Myllymaa, Sami Nikkonen
Publicado en:
Computer Methods and Programs in Biomedicine, Edición vol 226, 2022, ISSN 2169-3536
Editor:
Institute of Electrical and Electronics Engineers Inc.
DOI:
10.1016/j.cmpb.2022.107120
Autores:
M. Rusanen, R. Huttunen, H. Korkalainen, S. Myllymaa, J. Töyräs, K. Myllymaa, S.
Sigurdardottir, K. A. Olafsdottir, T. Leppänen, E. S. Arnardottir, S. Kainulainen
Publicado en:
IEEE Journal of Biomedical and Health Informatics, 2023, ISSN 2169-3536
Editor:
Institute of Electrical and Electronics Engineers Inc.
DOI:
10.1109/jbhi.2023.3240437
Autores:
Somaskandhan P, Leppänen T, Terrill PI,
Sigurdardottir S, Arnardottir ES, Ólafsdóttir KA,
Serwatko M, Sigurðardóttir SÞ, Clausen M,
Töyräs J and Korkalainen H
Publicado en:
Sleep Disorders, a section of the journal Frontiers in Neurology, 2023, ISSN 1664-2295
Editor:
Frontiers Research Foundation
DOI:
10.3389/fneur.2023.1162998
Autores:
Dirk Pevernagie, Fré A.Bauters, Katrien Hertegonne
Publicado en:
Sleep Medicine Clinics, Edición vol 16 (4), 2021, Página(s) 595-606, ISSN 1556-407X
Editor:
Elsevier BV
DOI:
10.1016/j.jsmc.2021.07.001
Autores:
Erna Sif Arnardottir; Anna Sigridur Islind; María Óskarsdóttir
Publicado en:
Sleep Medicine Clinics, Edición 16 (3), 2021, Página(s) 447-464, ISSN 1556-407X
Editor:
Elsevier BV
DOI:
10.1016/j.jsmc.2021.05.004
Autores:
S. Sillanmäki, J. Lipponen, H. Korkalainen, A. Kulkas, T. Leppänen, J. Töyräs, B. Duce, S. Kainulainen
Publicado en:
BMC Pulmonary Medicine volume 22, Article number: 204 (2022), Edición 14712466, 2022, ISSN 1471-2466
Editor:
BioMed Central
DOI:
10.1186/s12890-022-01996-y
Autores:
Emil Hardarson; Anna Sigridur Islind; Erna Sif Arnardottir; María Óskarsdóttir
Publicado en:
Current Sleep Medicine Reports, Edición 2, 2023, ISSN 2198-6401
Editor:
Springer Nature
DOI:
10.1007/s40675-023-00253-w
Autores:
T. Leppänen, S. Myllymaa, A. Kulkas, and J. Töyräs
Publicado en:
Sleep, Volume 44, Edición 9, September 2021, zsab134,, Edición 01618105, 2021, ISSN 0161-8105
Editor:
The American Academy of Sleep Medicine
DOI:
10.1093/sleep/zsab134
Autores:
Sturludóttir Jóna Elísabet, Sigurðardóttir Sigríður, Serwatko Marta, Arnardóttir Erna S., Hrubos-Strøm Harald, Clausen Michael Valur, Sigurðardóttir Sigurveig, Óskarsdóttir María, Islind Anna Sigridur
Publicado en:
Frontiers in Sleep, Edición Vol 2, 2023, ISSN 2813-2890
Editor:
Frontiers Media SA
DOI:
10.3389/frsle.2023.1082996
Autores:
B. Gailer; E. Richert; E.S. Arnardóttir; K.R. Jóhannsdóttir
Publicado en:
Neuroscience Applied, Edición 1, 2023, ISSN 2772-4085
Editor:
Amsterdam Elsevier B.V.
DOI:
10.1016/j.nsa.2023.103833
Autores:
Fábio Mendonça, Sheikh Shanawaz Mostafa, Ankit Gupta, Erna Sif Arnardottir, Timo Leppänen, Fernando Morgado-Dias, Antonio G Ravelo-García
Publicado en:
Sleep, 2022;, zsac217, Edición 01618105, 2022, ISSN 0161-8105
Editor:
The American Academy of Sleep Medicine
DOI:
10.1093/sleep/zsac217
Autores:
María Óskarsdóttir, Anna Sigríður Íslind, Elias August, Erna Sif Arnardóttir, François Patou, Anja M Maier
Publicado en:
JMIR Formative Research, Edición Vol 6, No 2 (2022): February, 2022, Página(s) 455, ISSN 2561-326X
Editor:
JMIR Publications
DOI:
10.2196/31807
Autores:
M. Rusanen, S. Kainulainen, H. Korkalainen, T. Leppänen, J. Töyräs, E.S. Arnardóttir, S. Myllymaa
Publicado en:
IEEE Access, Edición 21693536, 2021, ISSN 2169-3536
Editor:
Institute of Electrical and Electronics Engineers Inc.
DOI:
10.1109/access.2021.3128057
Autores:
Ida Alakörkkö, Soili Törmälehto, Timo Leppänen, Walter T. McNicholas, Erna S. Arnardottir, Reijo Sund,
Publicado en:
Sleep Medicine Reviews, Edición Volume 72, 2023, ISSN 1087-0792
Editor:
W. B. Saunders Co., Ltd.
DOI:
10.1016/j.smrv.2023.101854
Autores:
Henna Pitkänen , Brett Duce , Timo Leppänen , Samu Kainulainen , Antti Kulkas ,
Sami Myllymaa , Juha Töyräs , and Henri Korkalainen
Publicado en:
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING,, Edición vol 69, 2022, Página(s) 1417-1423, ISSN 2169-3536
Editor:
Institute of Electrical and Electronics Engineers Inc.
DOI:
10.1109/tbme.2021.3118229
Autores:
E.S. Arnardottir, A.S. Islind, M. Óskarsdóttir, K.A. Ólafsdóttir, E. August, L. Jónasdóttir, H. Hrubos-Strøm, J.M. Saavedra, L. Grote, J. Hedner, S. Höskuldsson, J. Skírnir Ágústsson, K. Rún Jóhannsdóttir, W.T. McNicholas, D. Pevernagie, R. Sund, J. Töyräs, T. Leppänen, On behalf of the Sleep Revolution
Publicado en:
J Sleep Res . 2022 Aug;31(4):e13630. doi: 10.1111/jsr.13630. Epub 2022 Jun 30., Edición 13652869, 2022, ISSN 1365-2869
Editor:
Journal of Sleep Research
DOI:
10.1111/jsr.13630
Autores:
Timothy P. Howarth; Tuomas Karhu; Samu Kainulainen; Xin Chen; Alaa Mahamid; Juha Töyräs; Timo Leppänen
Publicado en:
Sleep Medicine, Edición 20, 2023, ISSN 1389-9457
Editor:
Elsevier BV
DOI:
10.1016/j.sleep.2023.04.027
Autores:
Arie Oksenberg, Timo Leppänen
Publicado en:
Sleep Medicine Reviews, Edición vol 68, 2022, ISSN 2169-3536
Editor:
Institute of Electrical and Electronics Engineers Inc.
DOI:
10.1016/j.smrv.2022.101729
Autores:
Serajeddin Ebrahimian, Saara Sillanmäki, Salla Hietakoste, Brett Duce,
Antti Kulkas, Juha Töyräs, Timo Leppänen, Jukka A. Lipponen,
Samu Kainulainen
Publicado en:
Plos One, Edición 17 (12), 2022, ISSN 1932-6203
Editor:
Public Library of Science
DOI:
10.1371/journal.pone.0278520
Autores:
Walter T. McNicholas
Publicado en:
Med, Edición Vol 4 Edición 12, 2023, ISSN 2666-6340
Editor:
Elsevier
DOI:
10.1016/j.medj.2023.11.009
Autores:
Sami Nikkonen, Henri Korkalainen, Juha Töyräs & Timo Leppänen
Publicado en:
Nature, Edición 12, 2022, ISSN 2045-2322
Editor:
Nature Publishing Group
DOI:
10.1038/s41598-022-19892-0
Autores:
S. Ebrahimian, A. Nahvi, M. Tashakori, H. Salmanzadeh, O. Mohseni, and T. Leppänen
Publicado en:
Int J Environ Res Public Health, Edición 16604601, 2022, ISSN 1660-4601
Editor:
Int J Environ Res Public Health
DOI:
10.3390/ijerph191710736
Autores:
Jacopo Piccini; Elias August; Sami Leon Noel Aziz Hanna; Tiina Siilak; Erna Sif Arnardóttir
Publicado en:
Signals, Vol 4, Iss 4, Pp 877-891 (2023), Edición 2, 2023, ISSN 2624-6120
Editor:
Basel: MDPI AG
DOI:
10.3390/signals4040048
Autores:
Henri Korkalainen, Sami Nikkonen, Samu Kainulainen, Amit Krishna Dwivedi, Sami Myllymaa, Timo Leppänen, Juha Töyräs
Publicado en:
Sleep Medicine Clinics, Edición Volume 16, Edición 4,, 2021, Página(s) 545-556, ISSN 1556-407X
Editor:
Elsevier BV
DOI:
10.1016/j.jsmc.2021.07.003
Autores:
Kamilla Run Johannsdottir; Dimitri Ferretti; Birta Sóley Árnadóttir; Maria K. Jonsdottir
Publicado en:
Sleep Medicine Clinics, Edición 16 (4), 2021, Página(s) 575-593, ISSN 1556-407X
Editor:
Elsevier BV
DOI:
10.1016/j.jsmc.2021.08.002
Autores:
Fjola D. Sigurdardottir; Caroline Tonje Øverby; Sami Nikkonen; Tuomas Karhu; Toril Dammen; Inger Hilde Nordhus; Thea Thorshov; Gunnar Einvik; Samu Kainulainen; Timo Leppänen; Erna Sif Arnardottir; Juha Töyräs; Torbjørn Omland; Harald Hrubos‐Strøm
Publicado en:
Journal of sleep medicine, 2022, ISSN 1613-6810
Editor:
Wiley - V C H Verlag GmbbH & Co.
DOI:
10.1111/jsr.13581
Autores:
Salla Hietakoste; Tuomas Karhu; Saara Sillanmäki; Raquel Bailón; Thomas Penzel; Juha Töyräs; Timo Leppänen; Sami Myllymaa; Samu Kainulainen
Publicado en:
EJR - European Respiratory Journal, ERJ Open Research, Edición 8 (4), 2022, ISSN 2312-0541
Editor:
ERJ
DOI:
10.1183/23120541.00121-2022
Autores:
E. Richert; E.S. Arnardóttir; K.R. Jóhannsdóttir
Publicado en:
Crossref, Edición 20, 2023, ISSN 2772-4085
Editor:
Amsterdam Elsevier B.V.
DOI:
10.1016/j.nsa.2023.102535
Autores:
Jacopo Piccini, Elias August, María Óskarsdóttir, Erna Sif Arnardóttir
Publicado en:
Frontiers in Sleep, 2023, ISSN 2813-2890
Editor:
Frontiers Media SA
DOI:
10.3389/frsle.2023.1127697
Autores:
Riku Huttunen, Timo Leppanen, Brett Duce, Erna S Arnardottir, Sami Nikkonen, Sami Myllymaa, Juha Toyras, Henri Korkalainen
Publicado en:
IEEE Transactions on Biomedical Engineering, 2022, Página(s) 1-12, ISSN 2169-3536
Editor:
Institute of Electrical and Electronics Engineers Inc.
DOI:
10.1109/tbme.2022.3225268
Autores:
Michal Borsky, Marta Serwatko, Erna S Arnardottir, Jacky Mallett
Publicado en:
IEEE J Biomed Health Inform . 2022 Jul;26(7):3418-3426., Edición 21682194, 2022, ISSN 2168-2194
Editor:
Institute of Electrical and Electronics Engineers Inc.
DOI:
10.1109/jbhi.2022.3159727
Autores:
Tuomas Karhu, Timo Leppänen, Henri Korkalainen, Sami Myllymaa, Brett Duce, Juha Töyräs, Sami Nikkonen
Publicado en:
Sleep medicine, Edición vol. 100, 2022, Página(s) 479-486, ISSN 1389-9457
Editor:
Elsevier BV
DOI:
10.1016/j.sleep.2022.09.024
Autores:
Arie Oksenberg, Timo Leppänen
Publicado en:
Sleep Medicine Reviews, Edición vol 68, 2022, ISSN 2169-3536
Editor:
Institute of Electrical and Electronics Engineers Inc.
DOI:
10.1016/j.smrv.2022.101728
Autores:
Biedebach L, Rusanen M, Þórðarson B. Þ, Arnardóttir ES, Óskarsdóttir M, Nikkonen S, Korkalainen H, Myllymaa S, Töyräs J, Kainulainen S, Leppänen T and Islind AS
Publicado en:
Proceedings of the 56th Hawaii International Conference on System Sciences 2023 (HICSS), 2023
Editor:
HICSS
Autores:
Schmitz, L., Sveinbjarnarson, B. F., Gunnarsson, G. N., Davíðsson, Ó. A., Davíðsson, Þ. B., Arnardottir, E. S, Óskarsdóttir, M. & Islind, A. S.
Publicado en:
Americas Conference on Information Systems (AMCIS), Minneapolis, USA, August 2022, 2022
Editor:
Americas Conference on Information Systems (AMCIS)
Autores:
T. Leppänen, S. Kainulainen, H. Korkalainen, S. Sillanmäki, A. Kulkas, J. Töyräs, S. Nikkonen
Publicado en:
Advances in Experimental Medicine and Biology book series (AEMB,volume 1384), 2022, ISBN 978-3-031-06413-5
Editor:
Springer, Cham
DOI:
10.1007/978-3-031-06413-5_12
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