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Production and use of galacturonic acid as a building block for chemistry

Ziel

The main aims of the programme are as follows:
The design and operation of a pilot plant capable of producing galacturonic acid and salts.
The promotion of galacturonic acid as a versatile intermediate for the production of food and industrial additives.
Evaluation of galacturonic acid, galactonic acid and galactaric acid as calcium sequestrating agents in detergent and in metal surface treatment.
Evaluation of sweeteners and metabolism of L-galactose as a low calorie sweetener.
Preparation and evaluation of derivatives of galacturonic acid, galactonic acid and L-galactonolactone in the food and feed additives (eg in acidulents, wetting agents and emulsifying agents). A versatile intermediate for the production of food and industrial additives.
Price control and the environmental damage caused by fossil fuels has led the modern industrial and agricultural sectors to investigate the use of biological renewable raw materials as a potential alternative.
The coupling ofion exchange chromatography and electrodialysis has enabled the production of cheap yields of D-galacturonic acid.

Price control and the environmental damage caused by fossil fuels has led the modern industrial and agricultural sectors to investigate the use of biological renewable raw materials as a potential alternative.
A nitric oxidation process of D-galacturonic acid into galactaric acid has been developed. The constraints of a recycling process for nitrogen oxide vapors will not harm the economy of the process. Kilogramme yields of this acid are now available for validation tests in washing powder formulations, surface detergents and as food additives.

Price control and the environmental damage caused by fossil fuels has led the modern industrial and agricultural sectors to investigate the use of biological renewable raw materials as a potential alternative.
The complexing power of sodium galactarate, measured by specific calcium electrodes, has proved to be excellent when operating in synergy with boric acid, which is the bleaching agent usually used in washing powder formulations. The precipitation inhibition of calcium carbonate is slowed down by the addition of sodium galactarate. When evaluated in a real detergency test, without synergy with borates, it behaves in moderately hard water at least as well as sodium tripolyphosphate with which it is being compared.

Price control and the environmental damage caused by fossil fuels has led the modern industrial and agricultural sectors to investigate the use of biological renewable raw materials as a potential alternative.
Using gross hydrolysates and mixtures of anionic column regeneration, the optimum electrodialysis membranes have been selected and the protocol best adapted to problems of D- galacturonic acid purification has been defined.

Price control and the environmental damage caused by fossil fuels has led the modern industrial and agricultural sectors to investigate the use of biological renewable raw materials as a potential alternative. In order to obtain a tensioactive product being able to claim the eco product label D-galacturonic acid fatty esters are being developed through enzymatic channels. A screening of various lipases has shown the feasibility of this process with future optimization involving Candida cylindracea and Aspergillus niger lipases.

Price control and the environmental damage caused by fossil fuels has led the modern industrial and agricultural sectors to investigate the use of biological renewable raw materials as a potential alternative. Sterile confines and enclosures, and the metabolism cages necessary for the evaluation of L-galactose digestion have been developed. This will allow confirmation of the nonassimilation of this sugar.
Surprisingly, only limited efforts have been devoted to the preparation and use of galacturonic acid as a chemical intermediate despite its natural abundance (galacturonic acid is the major constituent of pectins which are present in significant proportion in sugar beet pulps, apples and citrus pulps) and its versatility as a chemical building block.

A comprehensive review of the scientific literature concerning galacturonic acid clearly shows that this product or its derivatives have remained laboratory curiosities and have never reached the pilot plant development level. Galacturonic, galatonic and galactic acids are known as good sequestrating agents {complexity of various anions such as Ca(2+), Mg(2+), Fe(3+)}. In addition the use of galacturonic salts and derivatives in pharmaceuticals, cosmetics and food additives was proposed in the 1960's and 1970's.

Unfortunately none reached the industrial development level probably due to the absence of a technique allowing the recovery of galacturonic acid at low prices and thus permitting competition with other hydroxylated carboxylic acids such as fumaric, malic, tartaric, citric and gluconic acids. Galacturonic acid obtained by hydrolysis of crude or purified pectins remained too expensive for most of the envisaged application possibilities until a process allowing an enzymatic recovery of galacturonic acid was developed. This process is based on the enzymatic liquefaction of root crops such as sugar beet and chicory. The enzymes mixtures used contain a wide range of glucanases capable of hydrolyzing the sugars (sucrose in sugar beet, inulin in chicory) as well as the cell walls constituting carbohydrates (pectins, hemicelluloses, cellulose) providing galacturonic acid which can be removed by ion exchange or by electrodialysis.

Wissenschaftliches Gebiet (EuroSciVoc)

CORDIS klassifiziert Projekte mit EuroSciVoc, einer mehrsprachigen Taxonomie der Wissenschaftsbereiche, durch einen halbautomatischen Prozess, der auf Verfahren der Verarbeitung natürlicher Sprache beruht. Siehe: Das European Science Vocabulary.

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Agro-Industries Recherches et Développements SA
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