Objectif Background :Despite intensive efforts, it has not proved possible to eradicate classical swine fever(CSF) in Europe and new outbreaks of the disease continue to occur within EU member states and Eastern Europe. Not only the direct costs but also the indirect costs, relating to international trade of both live pigs and pig products, of these outbreaks are enormous. In order to deal with outbreaks, there is a short term need for improved diagnosis and a longer term need for a better understanding of why the disease is reappearing. The objective is :This research proposal seeks to address both the need for improved CSF diagnosis and the need for identifying the routes of continuing disease spread. The former will be dealt with through the development, optimisation and harmonised validation of new diagnostic methods based on detection of CSF virus antigens and RNA; the latter through the development of molecular epizootiological methods to permit the origin and spread of outbreaks to be more precisely determined. Short description of the project :As regards diagnostic tests, particular emphasis will be placed on establishing tests based on reverse transcription - polymerase chain reaction (RT-PCR) for screening blood samples of live pigs and tissue from abattoir carcasses. Molecular epidemiology will be based on the establishment of a specific fingerprint for each outbreak that will be compared to others in order to determine the likely patterns of the spread. Champ scientifique natural sciencesbiological sciencesmicrobiologyvirologymedical and health scienceshealth sciencespublic healthepidemiologynatural sciencesbiological sciencesgeneticsRNAsocial scienceseconomics and businessbusiness and managementcommerce Programme(s) FP4-FAIR - Specific research, technological development and demonstration programme in the field of agriculture and fisheries (including agro-industry, food technologies, forestry, aquaculture and rural development), 1994-1998 Thème(s) 4.4.2 - Animal health Appel à propositions Data not available Régime de financement CSC - Cost-sharing contracts Coordinateur MAFF Central Veterinary Laboratory Contribution de l’UE Aucune donnée Adresse Woodham Lane New Haw Addlestone KT15 3NB Weybridge Royaume-Uni Voir sur la carte Coût total Aucune donnée Participants (6) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire HANNOVER VETERINARY SCHOOL - TIERARZTLICHE HOCHSCHULE HANNOVER Allemagne Contribution de l’UE Aucune donnée Adresse BUENTENWEG, 17 30559 HANNOVER Voir sur la carte Coût total Aucune donnée INSTITUTE OF VIROLOGY AND IMMUNOPROPHYLAXIS Suisse Contribution de l’UE Aucune donnée Adresse 3147 MITTELHAUSERN Voir sur la carte Coût total Aucune donnée Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche Italie Contribution de l’UE Aucune donnée Adresse Via G. Salvemini 1 06126 Perugia Voir sur la carte Coût total Aucune donnée NATIONAAL INSTITUUT VOOR DIERGENEESKUNDIG ONDERZOEK Belgique Contribution de l’UE Aucune donnée Adresse GROESELENBERG, 99 1180 BRUXELLES Voir sur la carte Coût total Aucune donnée NATIONAL VETERINARY INSTITUTE Suède Contribution de l’UE Aucune donnée Adresse HUSARGATAN, 3 751 23 UPPSALA Voir sur la carte Coût total Aucune donnée THE NATIONAL VETERINARY INSTITUTE Pologne Contribution de l’UE Aucune donnée Adresse AL.PARTYZANTOW, 57 24-100 PULAWY Voir sur la carte Coût total Aucune donnée
