Biodegradable polyalkenoate cements

Projektinformationen

ID Finanzhilfevereinbarung: FMBI961390

Startdatum

Enddatum

Finanziert unter

• Specific research and technological development programme in the field of the training and mobility of researchers, 1994-1998

Gesamtkosten € 0,00

EU-Beitrag Keine Daten

Koordiniert durch

University of Limerick
Ireland

Ziel

The objective of this project is to look at the feasibility of developing a biodegradable bone glue for fracture fixation in orthopaedic surgery. Recently glass polyalkenoate cements formed from poly(acrylic acid) and ion leachable glasses have been developed as chemically adhesive bone cements. However there is a clinical need for a degradable adhesive. The objective of the current project is to synthesise and characterise poly(B Malic Acid). Poly(B Malic Acid) has the same chemical structure as poly(acrylic acid), but has an ester group in the polymer backbone and will hydrolyse to Malic Acid a metabolite of the TCA cycle. The chemistry of cement formation between Poly(B Malic Acid) anci ion leachable fluorosilicate glasse subsequently will be investigated and te mechanical properties of suitable cements characterised.

Wissenschaftliches Gebiet

• medical and health sciences › clinical medicine › surgery
• natural sciences › chemical sciences › polymer sciences
• engineering and technology › materials engineering

Programm/Programme

• FP4-TMR - Specific research and technological development programme in the field of the training and mobility of researchers, 1994-1998

Thema/Themen

• 0302 - Post-doctoral research training grants

Aufforderung zur Vorschlagseinreichung

Data not available

Finanzierungsplan

RGI - Research grants (individual fellowships)

Koordinator

University of Limerick

• EU-Beitrag: Keine Daten
• Adresse: Plassey Technological Park ; 61 Limerick ; Irland
• Gesamtkosten: Keine Daten