Skip to main content
European Commission logo
français français
CORDIS - Résultats de la recherche de l’UE
CORDIS
CORDIS Web 30th anniversary CORDIS Web 30th anniversary
Contenu archivé le 2024-06-18

Development of new strategies for treatment of amoebiasis, the parasitic disease caused by entamoeba histolytica

Objectif

Our remain rationale is that surface receptor-based research could have clinical application to control infectious diseases. The aim is to provide new target molecules for better diagnosis, vaccine and prophylaxis. The disease of interest is amoebiasis caused by Entamoeba histolytica, a parasite that represents a major public health problem in Latin America. Pathogenesis involves colonization and invasion of the human intestine and requires the activity of amoebic receptors like the Eh112 complex involved in phagocytosis of cells. We aim to provide targets for therapy and give rational alternatives for control of amoebiasis by a multidisciplinary approach extending from cell and molecular biology to immunology and epidemiological analysis. Key aspect are: parasite targets on human cells, phagocytosis by activation of the cytoskeleton, seroprevalence of Eh112 in endemic areas and assessment of the immune response.

Champ scientifique (EuroSciVoc)

CORDIS classe les projets avec EuroSciVoc, une taxonomie multilingue des domaines scientifiques, grâce à un processus semi-automatique basé sur des techniques TLN.

Vous devez vous identifier ou vous inscrire pour utiliser cette fonction

Thème(s)

Data not available

Appel à propositions

Data not available

Régime de financement

CSC - Cost-sharing contracts

Coordinateur

INSTITUT PASTEUR
Contribution de l’UE
Aucune donnée
Adresse
Rue du Docteur Roux 25
75724 PARIS
France

Voir sur la carte

Coût total
Aucune donnée

Participants (4)