Objetivo It is proposed to examined the non-specific effects of BCG vaccination through three randomised trials with possible implications for immunisation policies in developing countries. It will be examined whether revaccination with BCG reduces mortality with 30%, whether BCG vaccination at birth of low birth weight children is associated with better BCG coverage and 25% lower mortality, and whether vitamin A supplementation simultaneously with BCG vaccination is associated with a 30% reduction in infant mortality. None of these measures are standard in the current immunisation programmes in developing countries; however, observational studies suggest that BCG vaccination may have non-specific beneficial effects. The impact on severe morbidity and hospitalisations, in particular from malaria, will also be examined through surveillance at the paediatric department. The possible immunological basis for non-specific effects will be examined. Ámbito científico medical and health scienceshealth sciencesinfectious diseasesmalariasocial sciencessociologydemographymortalitymedical and health sciencesbasic medicineimmunologyimmunisation Programa(s) FP5-INCO 2 - Programme for research, technological development and demonstration on "Confirming the international role of Community research,1998-2002" Tema(s) Data not available Convocatoria de propuestas Data not available Régimen de financiación CSC - Cost-sharing contracts Coordinador STATENS SERUM INSTITUT Aportación de la UE Sin datos Dirección 5,ARTILLERIVEJ 5 2300 KOEPENHAGEN Dinamarca Ver en el mapa Coste total Sin datos Participantes (4) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo LABORATORIO NACIONAL DE SAUDE PUBLICO Guinea-Bisáu Aportación de la UE Sin datos Dirección Ministerio de Saude Publica BISSAU Ver en el mapa Coste total Sin datos LEIDEN UNIVERSITY Países Bajos Aportación de la UE Sin datos Dirección Albinusdreef 2 2300 RC LEIDEN Ver en el mapa Coste total Sin datos MEDICAL RESEARCH COUNCIL Gambia Aportación de la UE Sin datos Dirección Faraja BANJUL Ver en el mapa Coste total Sin datos PROJECTO DE SAUDE DE BANDIM Guinea-Bisáu Aportación de la UE Sin datos Dirección BISSAU Ver en el mapa Coste total Sin datos
