Enantioselective synthesis of biologically important natural products and their analogues having anti-tumour, immunosuppressant as well as HMG-CoA reductase inhibitory activity

Informations projet

N° de convention de subvention: INTAS-93-1450

Projet clôturé

Date de début 1 Septembre 1994

Date de fin 31 Août 1995

Financé au titre de

• International Association for the promotion of cooperation with scientists from the independent states of the former Soviet Union (INTAS), 1993-

Coût total

Aucune donnée

Contribution de l’UE

€ 24 000,00

Coordonné par

Centre National de la Recherche Scientifique
France

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Résultats exploitables

Enantioselective synthesis of biologically important natural products and their analogues having anti-tumour, immunosuppressant as well as HMG-CoA reductase inhibitory activity

The goal of this project is the enantio and stereoselective synthesis of biologically important natural products and their analogues exhibiting anti-tumour and immunosuppressant properties as well as potential inhibitors of HMG-CoA reductase. Results: A number of biologically compounds exhibiting anti-tumour,immunosuppressant and HMG CoA-reductase inhibitory activity have been synthesized. The biological evaluation of these compounds including the toxicity tests may require another two years, if not more. About 15 scientific publications resulted from this co-operation. At the moment no patent has been submitted from the joint work.