Enantioselective synthesis of biologically important natural products and their analogues having anti-tumour, immunosuppressant as well as HMG-CoA reductase inhibitory activity

Informazioni relative al progetto

ID dell’accordo di sovvenzione: INTAS-93-1450

Progetto chiuso

Data di avvio 1 Settembre 1994

Data di completamento 31 Agosto 1995

Finanziato da

• International Association for the promotion of cooperation with scientists from the independent states of the former Soviet Union (INTAS), 1993-

Costo totale

Nessun dato

Contributo UE

€ 24 000,00

Coordinato da

Centre National de la Recherche Scientifique
France

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Risultati sfruttabili

Enantioselective synthesis of biologically important natural products and their analogues having anti-tumour, immunosuppressant as well as HMG-CoA reductase inhibitory activity

The goal of this project is the enantio and stereoselective synthesis of biologically important natural products and their analogues exhibiting anti-tumour and immunosuppressant properties as well as potential inhibitors of HMG-CoA reductase. Results: A number of biologically compounds exhibiting anti-tumour,immunosuppressant and HMG CoA-reductase inhibitory activity have been synthesized. The biological evaluation of these compounds including the toxicity tests may require another two years, if not more. About 15 scientific publications resulted from this co-operation. At the moment no patent has been submitted from the joint work.