Objetivo Salmon pancreas disease (SPD) and sleeping disease (SD) are emerging diseases of farmed salmon fish, that are caused by closely related, recently characterised alpha viruses. Due to the lack of diagnostics, the prevalences of these diseases are unknown but each is thought to be greatly under diagnosed. The primary aim of this project is to develop sensitive, specific, and easy-to-use diagnostic tests for SPD and SD. The project exploits recently acquired knowledge concerning the molecular characterisation of the viruses, to enable the production of improved reagents with which tests for detecting viral antigens and RNA in tissue samples, and virus-specific antibodies in fish sera, can be developed. Sensitive immunohistochemical and in site hybridisation methods will be used to improve the understanding of the pathogeneses of these diseases. Epidemiological aspects will also be studied by investigating the prevalence of infection using serological surveys of salmon and marine fish, by investigating the genetic diversity of virus isolates detected byre -PCR, and by investigating possible sources of infection. Ámbito científico natural sciencesbiological sciencesmicrobiologyvirologymedical and health scienceshealth sciencespublic healthepidemiologynatural sciencesbiological sciencesgeneticsRNA Programa(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Tema(s) 1.1.1.-2. - Key action Control of Infectious Diseases Convocatoria de propuestas Data not available Régimen de financiación CSC - Cost-sharing contracts Coordinador THE QUEEN'S UNIVERSITY OF BELFAST Aportación de la UE Sin datos Dirección Stoney Road , Stormont BT4 3SD BELFAST Reino Unido Ver en el mapa Coste total Sin datos Participantes (4) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo AGENCE FRANCAISE DE SECURITE SANITAIRE DES ALIMENTS Francia Aportación de la UE Sin datos Dirección Technopole Brest-Iroise 29280 PLOUZANE Ver en el mapa Coste total Sin datos INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE Francia Aportación de la UE Sin datos Dirección Domaine de Vilvert 78352 JOUY-EN-JOSAS Ver en el mapa Coste total Sin datos INTERVET NORBIO AS Noruega Aportación de la UE Sin datos Dirección Thormoehlensgate 55 5008 BERGEN Ver en el mapa Coste total Sin datos NORWEGIAN SCHOOL OF VETERINARY SCIENCE Noruega Aportación de la UE Sin datos Dirección Ullevaalsveien 72 0033 OSLO Ver en el mapa Coste total Sin datos