Skip to main content
European Commission logo print header
Contenuto archiviato il 2024-04-15

57FE MOESSBAUER SPECTROSCOPY OF FE II, III-ANTITUMOR DRUG-NUCLEIC ACID SYSTEMS: THE FE ENVIRONMENT IN THE PROCESS OF NUCLEIC ACID SCISSION

Obiettivo



The nature of the bonding environment and electronic state of Fe Atoms in the process of DNA strand scissioning by systems antibiotic Fe II, III would be investigated by 57 Fe Mossbaueur spectroscopy. The structure of complexes Fe-drug (-adriamycin,-bleomycin, et al.) as well as of model compounds and systems (such as Fe II,III complexes with nucleir acid constituents), would be also studied, preferably in solution phase, in order to possibly better understand and discuss the role of the metal in the scissioning.

Argomento(i)

Data not available

Invito a presentare proposte

Data not available

Meccanismo di finanziamento

CSC - Cost-sharing contracts

Coordinatore

Università degli Studi di Palermo
Contributo UE
Nessun dato
Indirizzo
Via Archirafi 26-28
90123 Palermo
Italia

Mostra sulla mappa

Costo totale
Nessun dato

Partecipanti (2)