Obiettivo The nature of the bonding environment and electronic state of Fe Atoms in the process of DNA strand scissioning by systems antibiotic Fe II, III would be investigated by 57 Fe Mossbaueur spectroscopy. The structure of complexes Fe-drug (-adriamycin,-bleomycin, et al.) as well as of model compounds and systems (such as Fe II,III complexes with nucleir acid constituents), would be also studied, preferably in solution phase, in order to possibly better understand and discuss the role of the metal in the scissioning. Campo scientifico natural sciencesbiological sciencesbiochemistrybiomoleculesnucleic acidsnatural sciencesbiological sciencesgeneticsDNAnatural sciencesphysical sciencesopticsspectroscopy Programma(i) FP1-STIMULATION 1C - Plan (EEC) to stimulate European scientific and technical cooperation and interchange, 1985-1988 Argomento(i) Data not available Invito a presentare proposte Data not available Meccanismo di finanziamento CSC - Cost-sharing contracts Coordinatore Università degli Studi di Palermo Contributo UE Nessun dato Indirizzo Via Archirafi 26-28 90123 Palermo Italia Mostra sulla mappa Costo totale Nessun dato Partecipanti (2) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto Medizinische Universität zu Lübeck Germania Contributo UE Nessun dato Indirizzo Ratzeburger Allee 160 23562 Lübeck Mostra sulla mappa Costo totale Nessun dato Università degli Studi di Padova Italia Contributo UE Nessun dato Indirizzo Via Marzolo 1 35131 Padova Mostra sulla mappa Costo totale Nessun dato