Obiettivo Objectives of the joint exchange program “DINaMiT” is to develop state-of-the art remotely responsive magnetic/metal nanoparticle functionalized drug delivery carriers for dual optical and magnetic resonance imaging modalities, equip such probes with theranostic detection/delivery capabilities and apply them for in-vivo study of anticancer drugs. To implement ambitious goals of such a program seven work-packages will be pursued. Each work-package will constitute of a necessary step for reaching the milestones and overall goals of the exchange programme.Functionalization of delivery carriers by nanoparticles is an important issue of successfully achieving the goals of the project. Optical imaging is the technique of choice for working with cell cultures and for routine fluorescent sample characterization. A significant advancement of the scientific research program is addition of magnetic response capabilities for such carriers, which results into dual optical / magnetically responsive system. Functionalized by nanoparticles, delivery carriers can be remotely activated based on the localized heating, which induces the permeability change of the carriers, but which does not affect the surrounding tissue. We envision using two-photon microscopy for deeper in-tissue reach. Magnetic functionality is viewed as a complementary approach which will allow even deeper reach. Magnetic resonance imaging (MRI) is a technique widely used for in-vivo diagnostic and tracking investigation.Polymeric and natural (red blood cells) delivery vehicles will be used for assembling ther-anostic carriers. Theranostic functionalities will be introduced by assembling the so-called multicompartment structures. Indeed, after such carriers are assembled and imaging/activation system is developed, in-vitro as well as in-vivo applications of such a system will be pursued. For in-vitro applications cell culture tests will be used, while that will be transferred for real in-vivo applications. Campo scientifico natural sciencesphysical sciencesopticsmicroscopymedical and health sciencesclinical medicineoncologyengineering and technologymedical engineeringdiagnostic imagingmagnetic resonance imagingengineering and technologynanotechnologynano-materials Programma(i) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Argomento(i) FP7-PEOPLE-2013-IRSES - Marie Curie Action "International Research Staff Exchange Scheme" Invito a presentare proposte FP7-PEOPLE-2013-IRSES Vedi altri progetti per questo bando Meccanismo di finanziamento MC-IRSES - International research staff exchange scheme (IRSES) Coordinatore CHARITE - UNIVERSITAETSMEDIZIN BERLIN Contributo UE € 140 300,00 Indirizzo Chariteplatz 1 10117 Berlin Germania Mostra sulla mappa Regione Berlin Berlin Berlin Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Mara-Theresa Klein (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Partecipanti (3) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto UNIVERSITEIT GENT Belgio Contributo UE € 43 800,00 Indirizzo SINT PIETERSNIEUWSTRAAT 25 9000 Gent Mostra sulla mappa Regione Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Evelien Vandevelde (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato UNIVERSITA DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO Italia Contributo UE € 36 800,00 Indirizzo DUOMO 6 13100 Vercelli Mostra sulla mappa Regione Nord-Ovest Piemonte Vercelli Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Ciro Isidoro (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato UNIVERSITA DEGLI STUDI DI TORINO Italia Contributo UE € 44 400,00 Indirizzo VIA GIUSEPPE VERDI 8 10124 Torino Mostra sulla mappa Regione Nord-Ovest Piemonte Torino Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Enzo Terreno (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato
