Objective Mental disorders are leading causes of disability, absence from work and premature retirement in Europe. While magnetic resonance imaging (MRI) facilities are broadly available and a vast research literature exists, few neuroimaging applications have reached clinical practice in psychiatry. A major problem is that mental illnesses are currently diagnosed as discrete entities defined clinically. Instead, recent results show that mental disorders are best understood as quantitative alterations in neural systems relevant across traditional diagnostic boundaries that reflect individual, genetic and environmental risk factors. In the IMAGEMEND consortium, we aim to discover these systems to identify the patient characteristics most relevant for treatment, derive biomarkers and decision rules from this systems-level dimensional account, and systematically validate biomarker panels in patient, high-risk and epidemiological samples to produce automated imaging-based diagnostic and predictive tests tailored for wide distribution throughout Europe in standard clinical settings. Focusing on schizophrenia, bipolar disorder and attention deficit-hyperactivity disorder, we have assembled Europe’s largest dataset combining neuroimaging, genetic, environmental, cognitive and clinical information on approximately 13000 participants, and have recruited international replication datasets of more than 30000 people. This unique resource will be processed using a new generation of multivariate statistical analysis to optimize existing imaging technology for the benefit of patients. We will also develop new imaging technology to enable the direct imaging-based therapeutic modification of neural circuits through rapid real-time MRI. Our deliverables will promote personalized treatment through more accurate patient stratification, allow diagnoses at the pre-symptomatic stage for early intervention and prevention, and improve prediction of treatment response and disease progression. Fields of science natural sciencesbiological sciencesgeneticsengineering and technologymedical engineeringdiagnostic imagingmagnetic resonance imagingmedical and health sciencesclinical medicinepsychiatryschizophrenia Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Topic(s) HEALTH.2013.2.2.1-2 - Development of effective imaging tools for diagnosis, monitoring and management of mental disorders Call for proposal FP7-HEALTH-2013-INNOVATION-1 See other projects for this call Funding Scheme CP-FP - Small or medium-scale focused research project Coordinator ZENTRALINSTITUT FUER SEELISCHE GESUNDHEIT EU contribution € 718 160,00 Address Square J 5 68159 Mannheim Germany See on map Region Baden-Württemberg Karlsruhe Mannheim, Stadtkreis Activity type Higher or Secondary Education Establishments Administrative Contact Andreas Meyer-Lindenberg (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (13) Sort alphabetically Sort by EU Contribution Expand all Collapse all KING'S COLLEGE LONDON United Kingdom EU contribution € 416 626,00 Address STRAND WC2R 2LS London See on map Region London Inner London — West Westminster Activity type Higher or Secondary Education Establishments Administrative Contact Paul Labbett (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSITAT BASEL Switzerland EU contribution € 420 000,00 Address PETERSPLATZ 1 4051 Basel See on map Region Schweiz/Suisse/Svizzera Nordwestschweiz Basel-Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Andreas Papassotiropoulos (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSITA DEGLI STUDI DI BARI ALDO MORO Italy EU contribution € 420 000,00 Address PIAZZA UMBERTO I 1 70121 Bari See on map Region Sud Puglia Bari Activity type Higher or Secondary Education Establishments Administrative Contact Delfina Maria Misuraca (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data THE UNIVERSITY OF EDINBURGH United Kingdom EU contribution € 420 000,00 Address OLD COLLEGE, SOUTH BRIDGE EH8 9YL Edinburgh See on map Region Scotland Eastern Scotland Edinburgh Activity type Higher or Secondary Education Establishments Administrative Contact Angela Noble (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data LIFE AND BRAIN GMBH Germany EU contribution € 720 000,00 Address VENUSBERG-CAMPUS 1 53127 Bonn See on map Region Nordrhein-Westfalen Köln Bonn, Kreisfreie Stadt Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Markus Noethen (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSITETET I OSLO Norway EU contribution € 420 000,00 Address PROBLEMVEIEN 5-7 0313 Oslo See on map Region Norge Oslo og Viken Oslo Activity type Higher or Secondary Education Establishments Administrative Contact Hans Mossin (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data STICHTING RADBOUD UNIVERSITEIT Netherlands EU contribution € 420 000,00 Address HOUTLAAN 4 6525 XZ Nijmegen See on map Region Oost-Nederland Gelderland Arnhem/Nijmegen Activity type Higher or Secondary Education Establishments Administrative Contact Marten Van Langen (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data ISLENSK ERFDAGREINING EHF Iceland EU contribution € 480 000,00 Address STURLUGOTU 8 101 Reykjavik See on map Region Ísland Ísland Höfuðborgarsvæði Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Frosti Jonsson (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data BRAIN INNOVATION BV Netherlands EU contribution € 780 000,00 Address OXFORDLAAN 55 6229 EV Maastricht See on map Region Zuid-Nederland Limburg (NL) Zuid-Limburg Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Claudia Goebel (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data CONCENTRIS RESEARCH MANAGEMENT GMBH Germany EU contribution € 300 000,00 Address Ludwigstr. 4 82256 FURSTENFELDBRUCK See on map Region Bayern Oberbayern Fürstenfeldbruck Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Ameli Schwalber (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN Germany EU contribution € 91 840,00 Address REGINA PACIS WEG 3 53113 Bonn See on map Region Nordrhein-Westfalen Köln Bonn, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Daniela Hasenpusch (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data QUEENSLAND INSTITUTE OF MEDICAL RESEARCH Participation ended Australia EU contribution No data Address Herston Road, 300 QLD 4006 Herston See on map Activity type Research Organisations Administrative Contact Lee Casey (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI United States EU contribution € 393 374,00 Address ONE GUSTAVE L LEVY PLACE BOX 1075 10029 6574 New York See on map Activity type Higher or Secondary Education Establishments Administrative Contact Allison Gottlieb (Mr.) Links Contact the organisation Opens in new window Total cost No data
