GENETIC AND BIOCHEMICAL BASIS OF RADIATION SENSITIVITY IN HUMAN AND OTHER MAMMALIAN CELLS IN CULTURE

Ziel

The result of the research supported the previous observation, that the ER response was somehow correlated with the induction of cancer. To study this correlation further, the ER response was determined in ultraviolet (UV) irradiated skin fibroblast from hereditary cancer prone syndromes. Interestingly, much higher levels of ER were observed in all these syndromes than in normal human skin fibroblast.
3. DNA REPAIR AND MUTAGENESIS.

EXPECTED BENEFITS

EVALUATION OF GENETIC RISKS FROM IONIZING RADIATION. DETERMINATION OF CELLULAR RADIOSENSITIVITY AND RELATION TO REPAIR.

Wissenschaftliches Gebiet

natural sciencesbiological sciencesgeneticsDNA
natural sciencesphysical sciencesnuclear physics
medical and health sciencesclinical medicineoncology

Programm/Programme

FP1-RADPROT 6C - Multiannual research and training programme (Euratom) in the field of radiation protection, 1985-1989

Thema/Themen

Data not available

Aufforderung zur Vorschlagseinreichung

Data not available

Finanzierungsplan

CSC - Cost-sharing contracts

Koordinator

RIJKSUNIVERSITEIT LEIDEN

EU-Beitrag

Keine Daten

Adresse

STATIONSWEG 46
2300 RA LEIDEN
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