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Role of Tumour Suppressor Gene Products of Common Fragile Sites in Human Diseases

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Publications

Tumor Suppressor Genes within Common Fragile Sites Are Active Players in the DNA Damage Response

Author(s): Idit Hazan, Thomas G. Hofmann, Rami I. Aqeilan
Published in: PLOS Genetics, Issue 12/12, 2016, Page(s) e1006436, ISSN 1553-7404
DOI: 10.1371/journal.pgen.1006436

Modeling WWOX Loss of Function in vivo: What Have We Learned?

Author(s): Mayur Tanna, Rami I. Aqeilan
Published in: Frontiers in Oncology, Issue 8, 2018, ISSN 2234-943X
DOI: 10.3389/fonc.2018.00420

Somatic loss of WWOX is associated with TP53 perturbation in basal-like breast cancer


Published in: ISSN 2041-4889
DOI: 10.1038/s41419-018-0896-z

WWOX controls hepatic HIF1α to suppress hepatocyte proliferation and neoplasia


Published in: ISSN 2041-4889
DOI: 10.1038/s41419-018-0510-4

WWOX Inhibits Metastasis of Triple-Negative Breast Cancer Cells via Modulation of miRNAs

Author(s): Saleh Khawaled, Sung Suk Suh, Suhaib K. Abdeen, Jonathan Monin, Rosario Distefano, Giovanni Nigita, Carlo M. Croce, Rami I. Aqeilan
Published in: Cancer Research, Issue 79/8, 2019, Page(s) 1784-1798, ISSN 0008-5472
DOI: 10.1158/0008-5472.can-18-0614

WWOX somatic ablation in skeletal muscles alters glucose metabolism

Author(s): Muhannad Abu-Remaileh, Monther Abu-Remaileh, Rania Akkawi, Ibrahim Knani, Shiran Udi, Micheal E. Pacold, Joseph Tam, Rami I. Aqeilan
Published in: Molecular Metabolism, Issue 22, 2019, Page(s) 132-140, ISSN 2212-8778
DOI: 10.1016/j.molmet.2019.01.010

Decoding the link between WWOX and p53 in aggressive breast cancer

Author(s): Suhaib K. Abdeen, Rami I. Aqeilan
Published in: Cell Cycle, Issue 18/11, 2019, Page(s) 1177-1186, ISSN 1538-4101
DOI: 10.1080/15384101.2019.1616998