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Brain-Specific, Modular and Active RNA Therapeutics


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Extracellular Vesicle Heterogeneity: Subpopulations, Isolation Techniques, and Diverse Functions in Cancer Progression

Author(s): Eduard Willms, Carlos Cabañas, Imre Mäger, Matthew J. A. Wood, Pieter Vader
Published in: Frontiers in Immunology, Issue 9, 2018, ISSN 1664-3224
DOI: 10.3389/fimmu.2018.00738

Functional Delivery of Lipid-Conjugated siRNA by Extracellular Vesicles

Author(s): Aisling J. O’Loughlin, Imre Mäger, Olivier G. de Jong, Miguel A. Varela, Raymond M. Schiffelers, Samir El Andaloussi, Matthew J.A. Wood, Pieter Vader
Published in: Molecular Therapy, Issue 25/7, 2017, Page(s) 1580-1587, ISSN 1525-0016
DOI: 10.1016/j.ymthe.2017.03.021

Nose-to-brain peptide delivery – The potential of nanotechnology

Author(s): Eleni Samaridou, Maria José Alonso
Published in: Bioorganic & Medicinal Chemistry, Issue 26/10, 2018, Page(s) 2888-2905, ISSN 0968-0896
DOI: 10.1016/j.bmc.2017.11.001

State-of-the-Art Design and Rapid-Mixing Production Techniques of Lipid Nanoparticles for Nucleic Acid Delivery

Author(s): Martijn J. W. Evers, Jayesh A. Kulkarni, Roy van der Meel, Pieter R. Cullis, Pieter Vader, Raymond M. Schiffelers
Published in: Small Methods, 2018, Page(s) 1700375, ISSN 2366-9608
DOI: 10.1002/smtd.201700375

Heterogeneity and interplay of the extracellular vesicle small RNA transcriptome and proteome

Author(s): Helena Sork, Giulia Corso, Kaarel Krjutskov, Henrik J. Johansson, Joel Z. Nordin, Oscar P. B. Wiklander, Yi Xin Fiona Lee, Jakub Orzechowski Westholm, Janne Lehtiö, Matthew J. A. Wood, Imre Mäger, Samir EL Andaloussi
Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
DOI: 10.1038/s41598-018-28485-9

PEG-PGA Enveloped CPP-RNA nanocomplexes (ENCPs) for the nose-to-brain RNA delivery and treatment of neurodegenerative diseases

Author(s): Eleni Samaridou Martijn Evers, Pieter Vader, Raymond Schiffelers Evgenia Salta, Hannah Walgrave, Bart De Strooper María José Alonso
Published in: 2018 Controlled Release Society (CRS) Annual Meeting, 2018