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Crimean-Congo Haemorrhagic Fever Vaccine

Objective

Natural epidemics and outbreaks of emerging viral epidemics are growing problems internationally. The general aim of the CCHFVaccine project is to develop and deliver a vaccine, which can significantly increase our capacity to control the situation of Crimean Congo Haemorrhagic fever (CCHF) disease on a global basis. The proposed work program on CCHF virus aims to build a multidisciplinary research network, able to deliver vaccine candidates, methods and procedures eligible for clinical trials, with a special focus on prevention. Thanks to the background, unique facilities and tools available among the consortium participants, CCHFVaccine will deliver tools for countering the threat of this infection in Europe and endemic areas of the world. This work program will attempt to fill gaps in CCHFV virus research on immunology and vaccinology. To achieve this overall aim, an intensive work plan will be put in place with the following specific objectives: i) to produce vaccine candidates, ii) to bring several unique animal models into front line vaccine research, iii) to validate and bring the most promising vaccine candidates to clinical trials, iv) to ensure that an immune mediated protection is adequately understood, v) to perform clinical trials at Phase I and ensure a strategy for the effective deployment and utilization in resource-poor countries, and vi) to link this project to public health bodies, NGOs and vaccine companies.
The proposed CCHFVaccine project will succeed in bringing together selected competitive advantages such as: operating capacity with appropriate facilities (state-of-the-art BSL-4s) and the only animal BSL-4 -with capacity to challenge domestic animals in Europe, highly experienced researchers in the development and evaluation of vaccine candidates, authorities and entities of human and animal health, clinical samples from endemic countries, and an international network proven to be functional by the previous EU-funded CCHFever and EDENext.

Call for proposal

H2020-SC1-2016-RTD
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

FOLKHALSOMYNDIGHETEN
Address
Nobels Vag 18
171 82 Solna
Sweden
Activity type
Other
EU contribution
€ 1 356 000

Participants (12)

INSERM TRANSFERT SA
France
EU contribution
€ 351 875
Address
Rue Watt 7
75013 Paris
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
JUSTUS-LIEBIG-UNIVERSITAET GIESSEN
Germany
EU contribution
€ 348 281,25
Address
Ludwigstrasse 23
35390 Giessen
Activity type
Higher or Secondary Education Establishments
Department of Health
United Kingdom
EU contribution
€ 348 000
Address
Quarry House, Quarry Hill
LS2 7UE Leeds
Activity type
Research Organisations
FRIEDRICH LOEFFLER INSTITUT - BUNDESFORSCHUNGSINSTITUT FUER TIERGESUNDHEIT
Germany
EU contribution
€ 505 000
Address
Sudufer 10
17493 Greifswald-insel Riems
Activity type
Research Organisations
KAROLINSKA INSTITUTET
Sweden
EU contribution
€ 2 199 576,05
Address
Nobels Vag 5
17177 Stockholm
Activity type
Higher or Secondary Education Establishments
NATIONAL CENTER OF INFECTIOUS AND PARASITIC DISEASES
Bulgaria
EU contribution
€ 80 000
Address
Blvd. Yanko Sakazov 26
1504 Sofia
Activity type
Research Organisations
SIVAS CUMHURIYET UNIVERSITESI
Turkey
EU contribution
€ 140 250
Address
Kayseri Caddesi
58140 Sivas
Activity type
Higher or Secondary Education Establishments
MINISTRIA E SHENDETESISE
Kosovo
EU contribution
€ 60 000
Address
Zagreb Street
10000 Pristina
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
STATENS VETERINAERMEDICINSKA ANSTALT
Sweden
EU contribution
€ 240 250
Address
Ulls Vaeg 2B
75189 Uppsala
Activity type
Research Organisations
TAJIK RESEARCH INSTITUTE OF PREVENTIVE MEDICINE
Tajikistan
EU contribution
€ 80 000
Address
61 Shevchenko Str
734025 Dushanbe
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
BUNDESINSTITUT FUR IMPFSTOFFE UND BIOMEDIZINISCHE ARZNEIMITTEL
Germany
EU contribution
€ 136 000
Address
Paul-ehrlich-strasse 51-59
63225 Langen
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
KAFKAS UNIVERSITESI
Turkey
EU contribution
€ 134 375
Address
Pasacayiri
36100 Kars
Activity type
Higher or Secondary Education Establishments