Immune Signatures for Therapy Stratification in Major Mood Disorders

Deliverables

Websites, patent fillings, videos etc. (4)

Website update M12

The 6 monthly update of the web-site www.moodinflame.eu (with a newsletters and photographs of our open houses

Website update M1

The 6 monthly update of the web-site www.moodinflame.eu (with a newsletters and photographs of our open houses

Website update M6

The 6 monthly update of the web-site www.moodinflame.eu (with a newsletters and photographs of our open houses

Website update M18

The 6 monthly update of the web-site www.moodinflame.eu (with a newsletters and photographs of our open houses

Documents, reports (5)

Kick off report

Report of the kick off meeting

First annual meeting report

Report of the first annual meeting of the general assembly

Data management plan

A data management plan

Ethical approval treatment as usual study

First study subject approvals package for the study with treatment as usual (simple recording of improvement of mood state in patients)

Ethical approval IL-2 study

First study subject approvals package for the low dose IL-2 clinical investigations

Publications

Peer reviewed articles (7)

Childhood Adversity and Current Stress are related to Pro- and Anti-inflammatory Cytokines in Major Depression

Author(s): Norbert Müller, Daniela Krause, Rike Barth, Aye-Mu Myint, Elif Weidinger, Waltraud Stettinger, Peter Zill, Hemmo Drexhage, Markus J. Schwarz
Published in: Journal of Affective Disorders, Issue 253, 2019, Page(s) 270-276, ISSN 0165-0327
DOI: 10.1016/j.jad.2019.04.088

Low-Grade Inflammation as a Predictor of Antidepressant and Anti-Inflammatory Therapy Response in MDD Patients: A Systematic Review of the Literature in Combination With an Analysis of Experimental Data Collected in the EU-MOODINFLAME Consortium

Author(s): Gara Arteaga-Henríquez, Maria S. Simon, Bianka Burger, Elif Weidinger, Annemarie Wijkhuijs, Volker Arolt, Tom K. Birkenhager, Richard Musil, Norbert Müller, Hemmo A. Drexhage
Published in: Frontiers in Psychiatry, Issue 10, 2019, ISSN 1664-0640
DOI: 10.3389/fpsyt.2019.00458

Markers of neuroinflammation influence measures of cortical thickness in bipolar depression

Author(s): Sara Poletti, Giovanni Leone, Thomas A. Hoogenboezem, Davide Ghiglino, Benedetta Vai, Harm de Wit, Annemarie J.M. Wijkhuijs, Clara Locatelli, Cristina Colombo, Hemmo A. Drexhage, Francesco Benedetti
Published in: Psychiatry Research: Neuroimaging, Issue 285, 2019, Page(s) 64-66, ISSN 0925-4927
DOI: 10.1016/j.pscychresns.2019.01.009

Editorial: Activation and de-activation of inflammatory pathways. The disequilibrium of immune-neuro-endocrine networks in psychiatric disorders

Author(s): Hemmo A Drexhage
Published in: Brain, Behavior, and Immunity, Issue 78, 2019, Page(s) 5-6, ISSN 0889-1591
DOI: 10.1016/j.bbi.2019.01.007

Genetic and environmental influences on circulating NK and T cells and their relation to bipolar disorder

Author(s): G. Snijders, R. Brouwer, S. Kemner, F. Bootsman, H. A. Drexhage, M. H. J. Hillegers
Published in: International Journal of Bipolar Disorders, Issue 7/1, 2019, ISSN 2194-7511
DOI: 10.1186/s40345-018-0139-3

Th17/T regulator cell balance and NK cell numbers in relation to psychosis liability and social stress reactivity

Author(s): J. Counotte, H.A. Drexhage, J.M. Wijkhuijs, R. Pot-Kolder, V. Bergink, H.W. Hoek, W. Veling
Published in: Brain, Behavior, and Immunity, Issue 69, 2018, Page(s) 408-417, ISSN 0889-1591
DOI: 10.1016/j.bbi.2017.12.015

The circulating levels of CD4+ t helper cells are higher in bipolar disorder as compared to major depressive disorder

Author(s): Karlijn Becking, Bartholomeus C.M. Haarman, Laura Grosse, Willem A. Nolen, Stephan Claes, Volker Arolt, Robert A. Schoevers, Hemmo A. Drexhage
Published in: Journal of Neuroimmunology, Issue 319, 2018, Page(s) 28-36, ISSN 0165-5728
DOI: 10.1016/j.jneuroim.2018.03.004