Deliverables Websites, patent fillings, videos etc. (3) Report for the on-site training provided and usage of the online system every 6 months We will report for the onsite training provided and usage of the online system 3D models generated from 4 different sources Patient specific minibrain and spinal cordorganoids generated from iPSCs of ALS SMA FTD and PD will be characterized Identification of neuropathological markers We will identify genes responsible for selective cell death and potential targets to modify ND disease progression Publications Conference proceedings (1) Human 3D cell culture systems to model and elucidate spinal muscular atrophy pathology and treatment Author(s): *S. CORTI1, I. FARAVELLI1, P. RINCHETTI1, S. MANCINELLI2, L. MAPELLI3, G. FOROTTI4, M. RIZZUTI4, C. CORDIGLIERI5, L. CALANDRIELLO4, S. TAMANINI1, N. BRESOLIN1, G. P. COMI1, S. LODATO2, M. NIZZARDO1 Published in: 2019 Publisher: SFN Peer reviewed articles (3) CSF transplantation of a specific iPSC-derived neural stem cell subpopulation ameliorates the disease phenotype in a mouse model of spinal muscular atrophy with respiratory distress type 1. Author(s): Forotti G1, Nizzardo M1, Bucchia M2, Ramirez A2, Trombetta E3, Gatti S4, Bresolin N5, Comi GP5, Corti S6. Published in: Experimental Neurology, 2019, ISSN 0014-4886 Publisher: Academic Press DOI: 10.1016/j.expneurol.2019.113041 iPSCs-Based Neural 3D Systems: A Multidimensional Approach for Disease Modeling and Drug Discovery Author(s): Gianluca Costamagna, Luca Andreoli, Stefania Corti, Irene Faravelli Published in: Cells, Issue 8/11, 2019, Page(s) 1438, ISSN 2073-4409 Publisher: Multidisciplinary Digital Publishing Institute DOI: 10.3390/cells8111438 Disease Modeling and Therapeutic Strategies in CMT2A: State of the Art Author(s): Kordelia Barbullushi, Elena Abati, Federica Rizzo, Nereo Bresolin, Giacomo P. Comi, Stefania Corti Published in: Molecular Neurobiology, Issue 56/9, 2019, Page(s) 6460-6471, ISSN 0893-7648 Publisher: Humana Press, Inc. DOI: 10.1007/s12035-019-1533-2 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
