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Quantitative T cell Immunology and Immunotherapy

Deliverables

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Publications

Counting generations in birth and death processes with competing Erlang and exponential waiting times

Author(s): Giulia Belluccini, Martın Lopez-Garcia, Grant Lythe, Carmen Molina-Paris
Published in: Scientific Reports, 2022, Page(s) 12:11289, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-022-14202-0

Why are cell populations maintained via multiple compartments?

Author(s): Flavia Feliciangeli, Hanan Dreiwi, Martín López-García, Mario Castro Ponce, Carmen Molina-París and Grant Lythe
Published in: Journal of the Royal Society Interface, 17425689, 2022, Page(s) 20220629, ISSN 1742-5689
Publisher: The Royal Society
DOI: 10.1098/rsif.2022.0629

Cyton2: A Model of Immune Cell Population Dynamics That Includes Familial Instructional Inheritance

Author(s): HoChan Cheon, Andrey Kan, Giulio Prevedello, Simone C. Oostindie, Simon J. Dovedi, Edwin D. Hawkins, Julia M. Marchingo, Susanne Heinzel, Ken R. Duffy, Philip D. Hodgkin
Published in: Frontiers in Bioinformatics, 1, 2021, ISSN 2673-7647
Publisher: Frontiers Media SA
DOI: 10.3389/fbinf.2021.723337

Quantifying T Cell Cross-Reactivity: Influenza and Coronaviruses

Author(s): Jessica Ann Gaevert, Daniel Luque Duque, Grant Lythe, Carmen Molina-París, Paul Glyndwr Thomas
Published in: Viruses, 13/9, 2021, Page(s) 1786, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v13091786

Resolving Fates and Single-Cell Transcriptomes of Hematopoietic Stem Cell Clones by PolyloxExpress Barcoding

Author(s): Weike Pei, Fuwei Shang, Xi Wang, Ann-Kathrin Fanti, Alessandro Greco, Katrin Busch, Kay Klapproth, Qin Zhang, Claudia Quedenau, Sascha Sauer, Thorsten B. Feyerabend, Thomas Höfer, Hans-Reimer Rodewald
Published in: Cell Stem Cell, 27/3, 2020, Page(s) 383-395.e8, ISSN 1934-5909
Publisher: Cell Press
DOI: 10.1016/j.stem.2020.07.018

Differentiation-based model of hematopoietic stem cell functions and lineage pathways

Author(s): Thomas Höfer, Hans-Reimer Rodewald
Published in: Blood, 132/11, 2018, Page(s) 1106-1113, ISSN 0006-4971
Publisher: American Society of Hematology
DOI: 10.1182/blood-2018-03-791517

Fate of a Naive T Cell: A Stochastic Journey

Author(s): Luis de la Higuera, Martín López-García, Mario Castro, Niloufar Abourashchi, Grant Lythe, Carmen Molina-París
Published in: Frontiers in Immunology, 10, 2019, ISSN 1664-3224
Publisher: Frontiers Media SA
DOI: 10.3389/fimmu.2019.00194

IL7 receptor signaling in T cells: A mathematical modeling perspective

Author(s): Jung‐Hyun Park, Adam T. Waickman, Joseph Reynolds, Mario Castro, Carmen Molina‐París
Published in: Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 11/5, 2019, ISSN 1939-5094
Publisher: John Wiley and Sons Inc.
DOI: 10.1002/wsbm.1447

Step‐by‐step comparison of ordinary differential equation and agent‐based approaches to pharmacokinetic‐pharmacodynamic models

Author(s): Van Thuy Truong, Paul G. Baverel, Grant D. Lythe, Paolo Vicini, James W. T. Yates, Vincent F. S. Dubois
Published in: CPT: Pharmacometrics & Systems Pharmacology, 2021, ISSN 2163-8306
Publisher: Nature Publishing Group
DOI: 10.1002/psp4.12703

Fate mapping of hematopoietic stem cells reveals two pathways of native thrombopoiesis

Author(s): Mina N. F. Morcos; Congxin Li; Clara M. Munz; Alessandro Greco; Nicole Dressel; Susanne Reinhardt; Katrin Sameith; Andreas Dahl; Nils B. Becker; Axel Roers; Thomas Höfer; Alexander Gerbaulet
Published in: Nature Communications, 20411723, 2022, Page(s) 4504, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-31914-z

No evidence that HLA genotype influences the driver mutations that occur in cancer patients

Author(s): Noor Kherreh, Siobhán Cleary, Cathal Seoighe
Published in: Cancer Immunology, Immunotherapy, 2021, ISSN 0340-7004
Publisher: Springer Verlag
DOI: 10.1007/s00262-021-03028-w

RBM-MHC: A Semi-Supervised Machine-Learning Method for Sample-Specific Prediction of Antigen Presentation by HLA-I Alleles

Author(s): Barbara Bravi, Jérôme Tubiana, Simona Cocco, Rémi Monasson, Thierry Mora, Aleksandra M. Walczak
Published in: Cell Systems, 12/2, 2021, Page(s) 195-202.e9, ISSN 2405-4712
Publisher: Cell Press
DOI: 10.1016/j.cels.2020.11.005

Current estimates of T cell kinetics in humans

Author(s): Derek C. Macallan, Robert Busch, Becca Asquith
Published in: Current Opinion in Systems Biology, 18, 2019, Page(s) 77-86, ISSN 2452-3100
Publisher: Elsevier Ltd
DOI: 10.1016/j.coisb.2019.10.002

Stochastic modelling of the T cell repertoire with epitope affinity

Author(s): Daniel F Luque Duque, Carmen Molina-Paris, Grant Lythe, Martin Lopez Garcia, Paul Glyndwr Thomas and Jessica Gaevert
Published in: The Journal of Immunology, 204 (1 Supplement), 2020, Page(s) 94.18, ISSN 1550-6606
Publisher: The American Association of Immunologists, Inc.