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Neo-PRISM-C: NEurodevelopmental Optimal-Predictors, Risk factors, and Intervention from a Systems approach to Maladjustment in Children

Project description

DEENESFRITPL

Innovative training network in systems approach to neurodevelopmental dysfunctions

Mental health disorders emerge early in development and result in neurodevelopmental dysfunctions (NDD), in many cases leading to long-term disability. Funded by the Marie Skłodowska-Curie Actions programme, the Neo-PRISM-C project constitutes a research training network to study NDD and to train early stage researchers from different disciplines in applying the research domain criteria (RDoC) approach, developed by the USA National Institute of Mental Health. Theoretical and predictive models in the RDoC approach address the significant heterogeneity and comorbidity in NDD. The network provides a new generation of researchers with the tools to improve understanding of behaviour and diagnosis, develop personalised treatments for NDD prevention and eliminate the disparities in underserved populations.

Objective

Mental health disorders pose a massive economic and societal burden. Emerging early in development and resulting in long-term disability, neurodevelopmental dysfunctions (NDD) compromise the quality of life of millions of Europeans. The purpose of the Neo-PRISM-C ETN is (1) to train Early Stage Researchers (ESRs) in applying the Research Domain Criteria, a novel framework for understanding psychopathology, to the study of the mechanisms and treatments of NDD. It aims (2) to train ESRs from multiple disciplines (psychology, neuroscience, data science) in state-of-the-art and transferable skills for innovating the study of brain-behavior relationships in NDD, in the context of a systems-based, trans-diagnostic theoretical frame. This ETN will also (3) support training in designing evidence-based, individualized treatments of learning, behavioral, and social maladjustment, bridging across diagnostic categories. Towards these goals, we have assembled a trans-sectoral European network with expertise in cognitive, social, educational, clinical, and emotion research and in training ESRs. Six research, training and management work packages (WPs) pursue these goals. WP1 comprises innovative projects, investigating risk and protective factors that span across NDD diagnostic categories (autism, learning, emotional difficulties) and linking to healthcare industry and education. WP2 examines systems-level brain development to identify biological substrates of specific dysfunctions. WP3 applies this knowledge to develop new multi-modal interventions to address domains of impairment. The academic, industrial and clinical partners collaborate across themes, offering ESRs project-specific secondments, supervision, workshops, summer school and courses on research, transferable and entrepreneurial skills. Neo-PRISM-C is expected to further understanding of NDD and improve the competitiveness of EU health professions, providing the market with highly-skilled researchers and clinicians.

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Topic(s)

Call for proposal

H2020-MSCA-ITN-2018

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Funding Scheme

MSCA-ITN - Marie Skłodowska-Curie Innovative Training Networks (ITN)

Coordinator

UNIVERSITY OF CYPRUS
Net EU contribution
€ 707 510,16
Address
AVENUE PANEPISTIMIOU 2109 AGLANTZI
1678 Nicosia
Cyprus

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Region
Κύπρος Κύπρος Κύπρος
Activity type
Higher or Secondary Education Establishments
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Total cost
€ 707 510,16

Participants (9)

Partners (7)

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Last update: 30 April 2024

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Permalink: https://cordis.europa.eu/project/id/813546

European Union, 2024