Project description DEENESFRITPL New biomechanical markers for early diagnostics It has long been proved that cell mechanics are related to various diseases and conditions. Funded by the Marie Skłodowska-Curie Actions programme, the Phys2BioMed project aims to identify and establish biomechanical markers for the early detection of cell and tissue dysfunction at the onset of disease. The objective is to create an interdisciplinary research training network for early stage researchers on the application of physical tools for the mechanical phenotyping of cells and tissues, developing novel early diagnostics. The network will merge training from diverse fields such as nanoscience and nanotechnology, physics, biology and medicine, defining the main features of new-generation instrumentation optimised for the mechanical phenotyping of clinical materials. Show the project objective Hide the project objective Objective Phys2BioMed will offer excellent interdisciplinary and cross-sectoral training to a team of motivated early stage researchers (ESRs) on the application of cutting-edge physical tools for the mechanical phenotyping of cells and tissues of clinical relevance, aiming at developing novel early-diagnostic tools. The Phys2BioMed network will merge diverse competences at European level, from different fields like nanoscience and nanotechnology, physics, biology, and medicine, and will expose ESRs to the non academic and private sector. A key element of the project is the peer-to-peer collaboration of research academic institutions with industries and world-leading medical and clinical centers; these are the main actors of the global challenge against diseases, and within Phys2BioMed they will highlight unmet clinical needs, and actively cooperate with academic colleagues for developing novel diagnostic strategies. ESRs will be trained-through-research by world-leading junior and senior PIs, and will benefit of lecture courses, dedicated international schools and workshops, and topical conferences. Secondments to other nodes of the network will represent the main and more effective channel of dissemination and cross-fertilization of competences, ideas, and knowledge within the network. Besides training talented young scientists, ready to work at the boundary of diverse disciplines in the field of nanomedicine, Phys2BioMed will provide scientific and technological outcomes on biomechanics, and the mechanical determinants of diseases. Technology-wise, it will define standardized procedures for nanomechanical measurements, and the definition of the main features of new-generation instrumentation optimized for the mechanical phenotyping of clinical specimens. In the longer-term, Phys2BioMed will provide the platform and know-how to build a data bank of mechanical fingerprints of diseases, setting the ground for the development of effective early-diagnostic tools. Fields of science engineering and technologynanotechnologymedical and health sciencesmedical biotechnologynanomedicinenatural sciencesbiological sciencesbiophysics Keywords Mechanics and rheology of cells tissues and ECMs in health and disease Cancer cells Mechanical phenotyping Early-Diagnostic Tools Standardization Atomic Force Microscopy Nanoindentation Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.1. - Fostering new skills by means of excellent initial training of researchers Topic(s) MSCA-ITN-2018 - Innovative Training Networks Call for proposal H2020-MSCA-ITN-2018 See other projects for this call Funding Scheme MSCA-ITN - Marie Skłodowska-Curie Innovative Training Networks (ITN) Coordinator UNIVERSITA DEGLI STUDI DI MILANO Net EU contribution € 522 999,36 Address Via Festa Del Perdono 7 20122 Milano Italy See on map Region Nord-Ovest Lombardia Milano Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 522 999,36 Participants (10) Sort alphabetically Sort by Net EU contribution Expand all Collapse all COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES France Net EU contribution € 274 802,04 Address RUE LEBLANC 25 75015 PARIS 15 See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 274 802,04 CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS France Net EU contribution € 549 604,08 Address RUE MICHEL ANGE 3 75794 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 549 604,08 CENTRE HOSPITALIER UNIVERSITAIRE DE GRENOBLE France Net EU contribution € 274 802,04 Address BOULEVARD DE LA CHANTOURNE 38700 La Tronche See on map Region Auvergne-Rhône-Alpes Rhône-Alpes Isère Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 274 802,04 FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA Spain Net EU contribution € 501 809,76 Address CARRER BALDIRI REIXAC PLANTA 2A 10-12 08028 Barcelona See on map Region Este Cataluña Barcelona Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 501 809,76 INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE France Net EU contribution € 274 802,04 Address RUE DE TOLBIAC 101 75654 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 274 802,04 UNIVERSITAET MUENSTER Germany Net EU contribution € 252 788,40 Address SCHLOSSPLATZ 2 48149 MUENSTER See on map Region Nordrhein-Westfalen Münster Münster, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 252 788,40 THE HENRYK NIEWODNICZANSKI INSTITUTE OF NUCLEAR PHYSICS, POLISH ACADEMY OF SCIENCES Poland Net EU contribution € 227 478,60 Address RADZIKOWSKIEGO 152 31 342 Krakow See on map Region Makroregion południowy Małopolskie Miasto Kraków Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 227 478,60 OSPEDALE SAN RAFFAELE SRL Italy Net EU contribution € 261 499,68 Address VIA OLGETTINA 60 20132 Milano See on map Region Nord-Ovest Lombardia Milano Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 261 499,68 UNIVERSITAET BREMEN Germany Net EU contribution € 505 576,80 Address Bibliothekstrasse 1 28359 Bremen See on map Region Bremen Bremen Bremen, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 505 576,80 OPTICS11 BV Netherlands Net EU contribution € 265 619,88 Address HETTENHEUVELWEG 37 1101 BM Amsterdam See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region West-Nederland Noord-Holland Groot-Amsterdam Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 265 619,88 Partners (5) Sort alphabetically Sort by Net EU contribution Expand all Collapse all Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. BIOMECA France Net EU contribution € 0,00 Address 60 AVENUE ROCKEFELLER 69008 Lyon See on map Region Auvergne-Rhône-Alpes Rhône-Alpes Rhône Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. VMICRO France Net EU contribution € 0,00 Address IEMN AVENUE POINTCARE 59652 VILLENEUVE D'ASCQ See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Hauts-de-France Nord-Pas de Calais Nord Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBERG Germany Net EU contribution € 0,00 Address SCHLOSSPLATZ 4 91054 Erlangen See on map Region Bayern Mittelfranken Erlangen, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE France Net EU contribution € 0,00 Address AVENUE OSCAR LAMBRET 2 59037 Lille See on map Region Hauts-de-France Nord-Pas de Calais Nord Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. UNIWERSYTET JAGIELLONSKI Poland Net EU contribution € 0,00 Address UL GOLEBIA 24 31-007 Krakow See on map Region Makroregion południowy Małopolskie Miasto Kraków Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data