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PD-MitoQUANT – A quantitative approach towards the characterisation of mitochondrial dysfunction in Parkinson's disease


Update on communication and dissemination activities

Update on communication and dissemination activities for different stakeholders, including patients

Dissemination and Communication Plan

Dissemination and Communication Plan, including timely open access publication of results (green or gold OA) and other dissemination activities (including via project website)

Data management & sharing plan (DMSP) - Interim

Data management & sharing plan (DMSP) - Interim

Data management & sharing plan (DMSP) - Initial

Data management & sharing plan (DMSP) - Initial veresion


α‐synuclein oligomers and fibrils: a spectrum of species, a spectrum of toxicities

Author(s): Parvez Alam, Luc Bousset, Ronald Melki, Daniel E. Otzen
Published in: Journal of Neurochemistry, Issue Volume150, Issue5 Special Issue: Synuclein Meeting 2019, 2019, Page(s) 522-534, ISSN 0022-3042
DOI: 10.1111/jnc.14808

The PINK1 kinase-driven ubiquitin ligase Parkin promotes mitochondrial protein import through the presequence pathway in living cells

Author(s): M. Jacoupy, E. Hamon-Keromen, A. Ordureau, Z. Erpapazoglou, F. Coge, J.-C. Corvol, O. Nosjean, C. Mannoury la Cour, M. J. Millan, J. A. Boutin, J. W. Harper, A. Brice, D. Guedin, C. A. Gautier, O. Corti
Published in: Scientific Reports, Issue 9/1, 2019, Page(s) 1-15, ISSN 2045-2322
DOI: 10.1038/s41598-019-47352-9

α-Synuclein conformational strains spread, seed and target neuronal cells differentially after injection into the olfactory bulb

Author(s): Nolwen L. Rey, Luc Bousset, Sonia George, Zachary Madaj, Lindsay Meyerdirk, Emily Schulz, Jennifer A. Steiner, Ronald Melki, Patrik Brundin
Published in: Acta Neuropathologica Communications, Issue 7/1, 2019, Page(s) 1-18, ISSN 2051-5960
DOI: 10.1186/s40478-019-0859-3

Differential Membrane Binding and Seeding of Distinct α-Synuclein Fibrillar Polymorphs

Author(s): Amulya Nidhi Shrivastava, Luc Bousset, Marianne Renner, Virginie Redeker, Jimmy Savistchenko, Antoine Triller, Ronald Melki
Published in: Biophysical Journal, Issue 27 January 2020, 2020, ISSN 0006-3495
DOI: 10.1016/j.bpj.2020.01.022

The expression level of alpha-synuclein in different neuronal populations is the primary determinant of its prion-like seeding

Author(s): Josquin Courte, Luc Bousset, Ysander Von Boxberg, Catherine Villard, Ronald Melki, Jean-Michel Peyrin
Published in: Scientific Reports, Issue 10/1, 2020, ISSN 2045-2322
DOI: 10.1038/s41598-020-61757-x

Interaction of the chaperones alpha B-crystallin and CHIP with fibrillar alpha-synuclein: Effects on internalization by cells and identification of interacting interfaces

Author(s): Maya Bendifallah, Virginie Redeker, Elodie Monsellier, Luc Bousset, Tracy Bellande, Ronald Melki
Published in: Biochemical and Biophysical Research Communications, Issue 17 May 2020, 2020, ISSN 0006-291X
DOI: 10.1016/j.bbrc.2020.04.091

AMPK preferentially depresses retrograde transport of axonal mitochondria during localised nutrient deprivation

Author(s): Orla Watters, Niamh M. C. Connolly, Hans-Georg König, Heiko Düssmann, Jochen H. M. Prehn
Published in: The Journal of Neuroscience, Issue 11 May 2020, 2020, Page(s) JN-RM-2067-19, ISSN 0270-6474
DOI: 10.1523/jneurosci.2067-19.2020