Project description
Innovative approach for advanced tissue engineering
Advancements in technology and 4D bioprinting enable new approaches in tissue engineering and regenerative medicine. With the support of the Marie Skłodowska-Curie Actions programme, the ProINK4D project will develop advanced protein-engineered biomaterials for 4D bioprinting of dynamic tissue constructs. The project draws inspiration from intrinsically disordered protein polymers (IDPPs) that exhibit lower and upper critical solution temperature (LCST and UCST) phase behaviours. It will create hybrid hydrogels by combining protein polymers with opposite thermoresponsive properties, leading to the development of preprogrammed, shape-morphing protein hydrogels. The comprehensive research plan covers bioproduction, material characterisation, bioink and bioresin optimisation, and advanced 4D bioprinting. The project will significantly impact scientific understanding and practical applications in tissue engineering and regenerative medicine.
Objective
The ProINK4D project embarks on a transformative journey to pioneer the development of next-generation protein-engineered biomaterials for 4D bioprinting of dynamic tissue constructs. Inspired by the intrinsic versatility of intrinsically disordered protein polymers (IDPPs) with lower and upper critical solution temperature (LCST and UCST) phase behaviors, this project aims to create hybrid hydrogels by ingeniously combining protein polymers exhibiting opposite thermoresponse properties. This innovative design strategy sets the stage for the creation of preprogrammed, shape-morphing protein hydrogels, paving the way for the development of responsive protein hydrogel actuators with enhanced efficiency. With a comprehensive research plan spanning bioproduction, material characterization, bioink and bioresin optimization, and advanced 4D bioprinting, ProINK4D promises to make a significant impact on both scientific understanding and practical applications in the realms of tissue engineering and regenerative medicine. Moreover, the project emphasizes rigorous project management, research innovation, and effective science communication to ensure the highest scientific quality and societal relevance of the generated knowledge and technology.
Fields of science (EuroSciVoc)
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2023-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
47002 VALLADOLID
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.