Obiettivo This three years project is concerned with the development of a Near-field (NF) THz absorption spectroscopy system with specific reference to the real-time characterization of bio-matter. This system will exploit electromagnetic resonance fingerprints (i.e. characteristic spectral responses). µm and sub-µm resolution will enable to spatially discriminate important low-energy materials resonances in bio-samples. The proposed research will allow the team members from INRS-EMT and CNR-INFM-SOFT, and their partners from the Univ. of Montreal and from McGill Univ., to lead the efforts in searching novel non-invasive investigation techniques. Our efforts will require a multidisciplinary approach, focused towards the following objectives: A: The design of a novel geometry for coherent THz generation. In-situ generation (THz radiation is generated at the interface with the sample) will be used to overcome the common power limitation of NF methods (resulting from to the limited aperture of the NF tip probing). Differential techniques will be used for subtracting the inorganic component contribution. In addition elicity control of the generated THz will be implemented in order to increase the discrimination of bio-compounds. Finally, Temporal time-domain-spectroscopy will be used for measuring the sample spectral resonances. B:THz spectroscopy of biopolymers. Amino acids, Proteins and DNA possess specific THz global and sub-global modes. Joining the interest of the involved partners in mapping biological compounds our test benches will be the detection of fundamental amino acid like Tyrosine and a fundamental alpha protein like human insulin. C:Experiments to demonstrate our ability to spatially (sub-wavelength) map a micrometric structure properly designed for mimicking the application on real biological tissue Campo scientifico natural sciencesbiological sciencesgeneticsDNAnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsnatural sciencesphysical sciencesopticsspectroscopyabsorption spectroscopynatural sciencesmathematicspure mathematicsgeometrynatural scienceschemical sciencesorganic chemistryamines Parole chiave Natural sciences Physical sciences Technological sciences Programma(i) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Argomento(i) PEOPLE-2007-4-1.IOF - Marie Curie Action: "International Outgoing Fellowships for Career Development" Invito a presentare proposte FP7-PEOPLE-2007-4-1-IOF Vedi altri progetti per questo bando Meccanismo di finanziamento MC-IOF - International Outgoing Fellowships (IOF) Coordinatore CONSIGLIO NAZIONALE DELLE RICERCHE Contributo UE € 217 645,77 Indirizzo PIAZZALE ALDO MORO 7 00185 Roma Italia Mostra sulla mappa Regione Centro (IT) Lazio Roma Tipo di attività Research Organisations Contatto amministrativo Francesca Calvi (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato