Objective Methicillin-resistant Staphylococcus aureus (MRSA) are of increasing concern both as community- and hospital-acquired pathogens. Since 2005, a specific clone, MRSA ST398 is spreading both in livestock populations and occupationally-exposed people resulting in human infection and disease in several EU Member States. The key objective of the PILGRIM project is to provide a range of novel control measures for the accelerated identification and control of emerging resistant bacteria. In order to achieve these we will undertake epidemiological and physiological studies of MRSA ST398 and use molecular approaches in well comparable animal models as well as humans in community and healthcare settings to 1) investigate/explore its biology and ecology, 2) identify and characterise factors determining the transmission pathways and risk from animal to human and between humans, 3) establish genetic differences, host-range and virulence of adhesive and non-adhesive strains as well as differences between ST398 and other MRSA, 3) identify specific genes for the development of new rapid tests to identify specific MRSA strains, 4) provide a Technology Testing Platform for developing and assessing decolonisation and environmental sanitation approaches, 5) integrate results in policy and practice guidelines. This project brings together clinical, genetic, microbiological and public health partners from 6 European countries, internationally renowned for their expertise in complementary ecosystems research. The two SME partners ensure the exploitation of results and the knowledge transfer, enabling associated companies to bring validated solutions to the market. The PILGRIM research will facilitate rapid and cost-effective measures to combat emerging resistant strains in order to prevent and eradicate community and nosocomial infections for better protection of citizens and patients in Europe and beyond. Fields of science medical and health scienceshealth sciencespublic healthnatural sciencesbiological sciencesmicrobiologybacteriologysocial sciencessociologygovernancecrisis managementagricultural sciencesanimal and dairy sciencedomestic animalsanimal husbandrymedical and health sciencesbasic medicinepharmacology and pharmacydrug resistanceantibiotic resistance Keywords MRSA-ST398 decolonisation environment decontamination epidemiological studies host-pathogen interaction intervention efficacy testing microarr nosocomial infection control transmission studies Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Topic(s) HEALTH-2007-2.3.1-4 - Molecular epidemiology to control nosocomial and community spreading of highly virulent multi-drug resistant strains of bacterial pathogens Call for proposal FP7-HEALTH-2007-B See other projects for this call Funding Scheme CP-FP - Small or medium-scale focused research project Coordinator THE ROYAL VETERINARY COLLEGE EU contribution € 559 448,00 Address ROYAL COLLEGE STREET NW1 OTU London United Kingdom See on map Region London Outer London — West and North West Barnet Activity type Higher or Secondary Education Establishments Administrative Contact Katharina Stärk (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (11) Sort alphabetically Sort by EU Contribution Expand all Collapse all STICHTING RADBOUD UNIVERSITEIT Netherlands EU contribution € 297 408,00 Address HOUTLAAN 4 6525 XZ Nijmegen See on map Region Oost-Nederland Gelderland Arnhem/Nijmegen Activity type Higher or Secondary Education Establishments Administrative Contact Hendrik-Jan Vos (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data KOBENHAVNS UNIVERSITET Denmark EU contribution € 497 585,00 Address NORREGADE 10 1165 Kobenhavn See on map Region Danmark Hovedstaden Byen København Activity type Higher or Secondary Education Establishments Administrative Contact Ivan Kristoffersen (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSITE LIBRE DE BRUXELLES Belgium EU contribution € 402 814,00 Address AVENUE FRANKLIN ROOSEVELT 50 1050 Bruxelles / Brussel See on map Region Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad Activity type Higher or Secondary Education Establishments Administrative Contact Philippe Vincke (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM Netherlands EU contribution € 137 204,00 Address DR MOLEWATERPLEIN 40 3015 GD Rotterdam See on map Region West-Nederland Zuid-Holland Groot-Rijnmond Activity type Higher or Secondary Education Establishments Administrative Contact Henri A. Verbrugh (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data ST GEORGE'S HOSPITAL MEDICAL SCHOOL United Kingdom EU contribution € 451 000,00 Address CRANMER TERRACE SW17 0RE London See on map Region London Inner London — West Wandsworth Activity type Higher or Secondary Education Establishments Administrative Contact Carolyn Doughty (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU Netherlands EU contribution € 85 896,00 Address Antonie Van Leeuwenhoeklaan 9 3721 MA Bilthoven See on map Region West-Nederland Utrecht Utrecht Activity type Research Organisations Administrative Contact Marjon Straver-Hartwigsen Links Contact the organisation Opens in new window Website Opens in new window Total cost No data STATENS SERUM INSTITUT Denmark EU contribution € 194 359,00 Address ARTILLERIVEJ 5 2300 Kobenhavn S See on map Region Danmark Hovedstaden Byen København Activity type Research Organisations Administrative Contact Robert Skov (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data VYSOKA SKOLA CHEMICKO-TECHNOLOGICKA V PRAZE Czechia EU contribution € 67 800,00 Address TECHNICKA 5 166 28 Praha See on map Region Česko Praha Hlavní město Praha Activity type Higher or Secondary Education Establishments Administrative Contact Anna Mittnerova (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data CENTRUM VOOR ONDERZOEK IN DIERGENEESKUNDE EN AGROCHEMIE - CODA Belgium EU contribution € 82 780,00 Address Groeselenberg 99 1180 BRUXELLES See on map Activity type Research Organisations Administrative Contact Eefje Tuerlinckx Links Contact the organisation Opens in new window Website Opens in new window Total cost No data AGUACURE LIMITED United Kingdom EU contribution € 73 950,00 Address ALUN ROBERTS BUILDING 9THE FLOOR LL57 2UW BANGOR See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact John Bostock Links Contact the organisation Opens in new window Website Opens in new window Total cost No data ACCELOPMENT SCHWEIZ AG Switzerland EU contribution € 143 580,00 Address SEEFELDSTRASSE 198 8008 ZURICH See on map Region Schweiz/Suisse/Svizzera Zürich Zürich Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Jeanette Müller (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data