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Active wound dressings based on biological mimicry

Ziel

The aim of the Bacteriosafe consortium is to construct, test and develop a unique active wound dressing, which incorporates novel colourimetric sensor and active therapeutic processes for detecting and counteracting pathogenic bacteria in wounds. The inspiration for this project is the natural nano-biological mechanism of bacterial attack on healthy cells. The outer cell walls are ruptured by an array of protein toxins, lipases and other enzymes secreted by these bacteria. We mimic this natural process by using these pathogenic factors to liberate engineered and biologically derived antibiotics/antimicrobials and indicating molecules from highly designed surface immobilized nanocapsules. This will minimize the need for frequent traumatic changes of wound dressing and will provide a simple optical indicator of bacterial infection. In addition to a significant cost reduction, the proposed dressing will minimize the time required for the analysis of bacterial infection. This is particularly critical in burn wounds where delayed detection of bacterial infection can result in patient death. The project will cover both the research into the basic mechanisms of device operation, the development of a prototype device and the process engineering which is necessary to prepare it for large scale industrial production.

Wissenschaftliches Gebiet

Programm/Programme

Thema/Themen

Aufforderung zur Vorschlagseinreichung

FP7-NMP-2009-SMALL-3
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Finanzierungsplan

CP-FP - Small or medium-scale focused research project

Koordinator

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
EU-Beitrag
€ 1 037 000,00
Adresse
HOFGARTENSTRASSE 8
80539 Munchen
Deutschland

Auf der Karte ansehen
Region
Bayern Oberbayern München, Kreisfreie Stadt
Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Udo Schreiner (Mr.)
Links
Gesamtkosten
Keine Daten

Beteiligte (10)

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Letzte Aktualisierung: 25 Mai 2017

Mein Booklet

Permalink: https://cordis.europa.eu/project/id/245500/de

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