Objetivo The global frequency of neonatal sepsis is 1-21 newborns per 1000 live births with mortality rates as high as 35-70%, amounting to 100,000s of annual cases. The consortium has identified a real and pressing need for increasing diagnostic efficacy in a setting that imposes a dramatic healthcare burden on EU (and global) healthcare management systems. The goal of this project is the realization and clinical validation of a fully integrated and automated platform for the parallel detection of neonatal sepsis markers and a panel of sepsis-causing bacteria from a clinical sample (whole blood, cerebrospinal fluid, fluid from joint aspirations or urine). For the first time, this will allow a fast (90 minutes) automated routine diagnosis of neonatal sepsis, permitting a timely and especially specific treatment.The project has the potential to significantly reduce neonatal mortality and ensure appropriate treatment for one of the most vulnerable patient cohorts in the medical setting: newborns. The interaction between presence of microbial pathogens and the host (patient) response will be investigated in a clinical validation phase with a view to planning patient management more appropriately. In the long term this will also reduce the spread of multiresistant strains emerging from the unspecific use of broad-spectrum antibiotics.ASCMicroPlat will cover the complete value chain from research and development to clinical validation. The system will be based on the centrifugal microfluidic platform of HSG-IMIT and an inventive foil-technology for the disposable test carriers, which is scalable to industrial production. ASCMicroPlat will enable a sepsis diagnosis based on a “sample in – result out” process. Additionally, the know-how generated in this project will provide innovative European SMEs with a platform for the fast implementation of lab-on-a-chip tests. The consortium has a strong industrial component including 2 SMEs. Ámbito científico natural sciencesphysical sciencesclassical mechanicsfluid mechanicsmicrofluidicssocial sciencessociologydemographymortalitynatural sciencesbiological sciencesmicrobiologybacteriologyengineering and technologyother engineering and technologiesmicrotechnologylab on a chipmedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsantibiotics Programa(s) FP7-HEALTH - Specific Programme "Cooperation": Health Tema(s) HEALTH.2010.1.2-1 - Tools for the identification and the detection of biomarkers in clinical samples and patients. FP7-HEALTH-2010-two-stage. Convocatoria de propuestas FP7-HEALTH-2010-two-stage Consulte otros proyectos de esta convocatoria Régimen de financiación CP-FP - Small or medium-scale focused research project Coordinador HAHN-SCHICKARD-GESELLSCHAFT FUR ANGEWANDTE FORSCHUNG EV Aportación de la UE € 668 254,00 Dirección WILHELM SCHICKARD STRASSE 10 78052 Villingen Schwenning Alemania Ver en el mapa Región Baden-Württemberg Freiburg Schwarzwald-Baar-Kreis Tipo de actividad Research Organisations Contacto administrativo Saskia Scherer (Ms.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos Participantes (4) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN Irlanda Aportación de la UE € 488 315,00 Dirección COLLEGE GREEN TRINITY COLLEGE D02 CX56 DUBLIN 2 Ver en el mapa Región Ireland Eastern and Midland Dublin Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Deirdre Savage (Ms.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos ROHRER AG WERKZEUG- & MASCHINENBAU Suiza Aportación de la UE € 244 975,00 Dirección BREMENSTALLSTRASSE 1 4313 MOHLIN Ver en el mapa Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Contacto administrativo Reto Kägi (Mr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos Mobidiag Oy Finlandia Aportación de la UE € 485 083,00 Dirección Tukholmankatu 00290 Helsinki Ver en el mapa Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Contacto administrativo Antti Ojala (Mr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos CHIMERA BIOTEC GMBH Alemania Aportación de la UE € 75 000,00 Dirección EMIL-FIGGE-STRASSE 76A 44227 DORTMUND Ver en el mapa Región Nordrhein-Westfalen Arnsberg Dortmund, Kreisfreie Stadt Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Contacto administrativo Jan Detmers (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos