Objective
Lewis acids-promoted reactions of organic compounds have been extensively studied in recent years. Many region-, diastereo-and enantioselective reactions catalyzed by a wide variety of Lewis acids have been reported. Still they often have major drawbacks when applied to large scale synthesis: (1) use of toxic metal-derived catalysts, (2) low turn-over, (3) formation of large amounts of salts, (4) low chemoselectivity when applied to polyfunctional reactants, (5) extensive use of control elements ( activating or protecting groups), (6) use of significant amounts of solvents. A few years ago a new class of silicon-derived superacids ( trialkylsilyl triflimides) has been discovered by the group of Ghosez. These environmentally-friendly catalysts have received much attention in recent years.
Our project is (1) to prepare a new class of tuneable silicon-derived “green” catalysts, (2) to test the catalytic activity of these new Lewis acids in representative reactions ( Diels-Alder, aldol, benzylation, allylation, Friedel-Crafts alkylation), (3) to prepare chiral catalysts (4) to test these catalyst in enantioselective syntheses.
The candidate has a background in synthesis of bioactive compounds. He is now completing his training at the European Institute of Chemistry and Biology(IECB) in Pessac in the group of Prof. L. Ghosez. The training programme has been designed to ensure that the candidate’s ambition to acquire a broad formation in synthetic chemistry and pursue a career in that field will be fulfilled. Presently he works on a project supported by industry and is being trained in total synthesis of natural products analogs using original approaches which will required the development of new environmentally friendly catalysts.
Training will be provided by the host group Ghosez at IECB. Additionally the candidate will benefit from the multidisciplinary character of the Institute where organic chemists, physical chemists and biologists interact everyday.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
You need to log in or register to use this function
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2010-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
33405 TALENCE
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.