Project description DEENESFRITPL Optimised nanoparticles for medical applications Nanotechnology offers great promise in medicine with nanomaterials serving as therapeutic modalities. They can be functionalised with biological moieties such as sugars or antibodies to guide resulting nanoparticles to specific targets within the body, and they can also serve as carriers of drugs. The mission of the EU-funded NanoCarb project is to improve the translation from bench to clinic of nanotechnology-related findings. Researchers have developed a platform for synthesising novel nanoparticles functionalised with glycans with optimal interacting properties upon exposure to biological environments. This platform will pave the way for a more streamlined testing process and safe nanoparticles for various healthcare applications. Show the project objective Hide the project objective Objective The advance of nanomedicine requires the development of novel materials with tailored properties, controlled circulation, optimal targeting and therapeutic efficacy after administration. Nanomaterials engineered with glycans offer multiple possibilities for nanomedicine as these biomolecules when arranged on a nanomaterial surface display strong binding to specific receptors while at the same time the glyco coating can restrict unspecific interactions with proteins, helping to avoid the mononuclear phagocyte system and improved biocompatibility in vivo.The NanoCarb Network will develop novel and well-characterised nanomaterials with synthetic and native N-glycans that will be used for therapeutics and guide development of new drug delivery applications. The project will train early stage researchers at the interface of nanotechnology and glycosciences, with the overall goal of achieving a new generation of professionals in nanomedicine for a prospective career in both academia and industry.To achieve this goal a multidisciplinary consortium has been created including universities, research centres and SMEs with broad expertise ranging from nanotechnology, carbohydrate chemistry, glycoprofiling and in vitro – in vivo screening specialists. An ambitious training plan will be implemented including courses, outreach activities, participation in seminar, and workshops for the development of scientific and transferable skills. Fields of science natural sciencesbiological sciencesbiochemistrybiomoleculesproteinsmedical and health sciencesmedical biotechnologynanomedicineengineering and technologymaterials engineeringcoating and filmsnatural sciencesbiological sciencesbiochemistrybiomoleculescarbohydratesengineering and technologynanotechnologynano-materials Keywords bionano interactions corona sugars glycans carbohydrates Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.1. - Fostering new skills by means of excellent initial training of researchers Topic(s) MSCA-ITN-2018 - Innovative Training Networks Call for proposal H2020-MSCA-ITN-2018 See other projects for this call Funding Scheme MSCA-ITN - Marie Skłodowska-Curie Innovative Training Networks (ITN) Coordinator ROYAL COLLEGE OF SURGEONS IN IRELAND Net EU contribution € 1 278 045,10 Address ST STEPHEN'S GREEN 123 2 Dublin Ireland See on map Region Ireland Northern and Western Border Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 1 278 045,10 Participants (9) Sort alphabetically Sort by Net EU contribution Expand all Collapse all THE UNIVERSITY OF WARWICK United Kingdom Net EU contribution € 606 345,12 Address Kirby Corner Road - University House CV4 8UW Coventry See on map Region West Midlands (England) West Midlands Coventry Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 606 345,12 UNIVERSITA DEGLI STUDI DI MILANO Italy Net EU contribution € 261 499,68 Address Via Festa Del Perdono 7 20122 Milano See on map Region Nord-Ovest Lombardia Milano Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 261 499,68 ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE Spain Net EU contribution € 501 809,76 Address PASEO MIRAMON 182, PARQUE TECNOLOGICO DE SAN SEBASTIAN EDIFICIO EMPRESARIAL C 20009 San Sebastian See on map Region Noreste País Vasco Gipuzkoa Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 501 809,76 VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V. Belgium Net EU contribution € 256 320,00 Address BOERETANG 200 2400 Mol See on map Region Vlaams Gewest Prov. Antwerpen Arr. Turnhout Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 256 320,00 LUDGER LIMITED United Kingdom Net EU contribution € 303 172,56 Address CULHAM SCIENCE CENTRE - BUILDING E1 OX14 3EB Abingdon See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 303 172,56 MIDATECH LTD Participation ended United Kingdom Net EU contribution € 0,00 Address ODDFELLOWS HOUSE 19 NEWPORT ROAD CF24 0AA Cardiff See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Wales East Wales Cardiff and Vale of Glamorgan Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI Italy Net EU contribution € 522 999,36 Address VIA MARIO NEGRI 2 20156 Milano See on map Region Nord-Ovest Lombardia Milano Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 522 999,36 MIDATECH PHARMA ESPANA SL Participation ended Spain Net EU contribution € 174 239,50 Address PARQUE TECNOLOGICO DE BIZKAIA EDIFICIO 800 2A PLANTA 48160 Derio See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Noreste País Vasco Bizkaia Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 174 239,50 CONSIGLIO NAZIONALE DELLE RICERCHE Italy Net EU contribution € 170 701,18 Address PIAZZALE ALDO MORO 7 00185 Roma See on map Region Centro (IT) Lazio Roma Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 170 701,18 Partners (6) Sort alphabetically Sort by Net EU contribution Expand all Collapse all Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. UNIVERSITEIT HASSELT Belgium Net EU contribution € 0,00 Address MARTELARENLAAN 42 3500 Hasselt See on map Region Vlaams Gewest Prov. Limburg (BE) Arr. Hasselt Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. FUNDACAO DA FACULDADE DE CIENCIAS E TECNOLOGIA DA UNIVERSIDADE NOVA DE LISBOA. Portugal Net EU contribution € 0,00 Address Campus de Caparica, Quinta da Torre S/N 2829516 Caparica See on map Region Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. MYBIOTECH GMBH Germany Net EU contribution € 0,00 Address INDUSTRIESTRASSE 1B 66802 Uberherrn See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Saarland Saarland Saarlouis Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. ATTANA AB Sweden Net EU contribution € 0,00 Address GREV TUREG 14 3 1/2 TR 114 46 Stockholm See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Östra Sverige Stockholm Stockholms län Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. HORIZONS UNLEASHED LTD United Kingdom Net EU contribution € 0,00 Address GLOBE HOUSE ECLIPSE PARK STITTINGBOURNE ROAD ME14 3EN Maidstone See on map Region South East (England) Kent Mid Kent Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. ACCELOPMENT SCHWEIZ AG Switzerland Net EU contribution € 0,00 Address SEEFELDSTRASSE 198 8008 ZURICH See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Schweiz/Suisse/Svizzera Zürich Zürich Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data
