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Real-time Adaptive Particle Therapy of Cancer

Project description

Personalised particle therapy

Particle therapy (PT) is a form of radiotherapy that targets tumours with high accuracy, sparing healthy surrounding tissue. However, PT in its current format is time consuming and lacks flexibility, rendering it unsuitable for personalised treatments. To exploit the full benefits of PT, further optimisation is required related to changes in anatomy or organ motion. The EU-funded RAPTOR project aims to address these limitations and advance PT for real-time use. The project involves key industrial leaders, ensuring the rapid translation of the findings into innovative and marketable solutions that can be implemented in the clinic.

Objective

The Real-time Adaptive Particle Therapy Of CanceR (RAPTOR) consortium comprises world-class research institutes, non-academic particle therapy (PT) centres and industrial providers of PT equipment, offering a platform for intercultural, interdisciplinary and intersectoral training of early stage researchers (ESRs) in the field of medical physics with a focus on real-time adaptive PT. This comprehensive expertise and infrastructure is required to address and solve challenges in the clinical implementation of real-time adaptive PT.
PT is an advanced type of radiotherapy used to treat a constantly rising number of cancer patients. PT allows to target tumour with a high accuracy while sparing healthy surrounding tissue from dose. However, changes in anatomy or positioning and organ motion give rise to uncertainties which need to be further minimized to exploit the full benefits of PT. Adapting PT plans in real time has the potential to provide truly personalized treatments, allowing for better target control and less toxicity. A move towards wide clinical implementation of adaptive PT approaches is currently prohibited by (i) stepwise treatment workflows that are time-consuming and largely manual, (ii) the inflexibility of commercial PT equipment, and (iii) the wide range of PT equipment and protocols.
RAPTOR ESRs will conduct research projects at both academic and non-academic health care facilities which will sharpen their focus on clinical needs with respect to real-time adaptive PT. The active involvement of industry ensures that the transfer of industry-relevant skills is an integral part of individual ESR projects. This will guarantee rapid translation of clinical needs into innovative and marketable solutions.
RAPTOR aims to train a new generation of researchers, enabling a paradigm shift from treatment approaches that are manual and stepwise to those that are automatic and seamless, while assuring standardized clinical implementation of real-time adaptive PT.

Fields of science (EuroSciVoc)

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Keywords

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Programme(s)

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Topic(s)

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-ITN - Marie Skłodowska-Curie Innovative Training Networks (ITN)

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-ITN-2020

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Coordinator

PAUL SCHERRER INSTITUT
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 562 553,28
Address
FORSCHUNGSTRASSE 111
5232 Villigen Psi
Switzerland

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Region
Schweiz/Suisse/Svizzera Nordwestschweiz Aargau
Activity type
Research Organisations
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 562 553,28

Participants (12)

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