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Marine Biodiversity as Sustainable Resource of Disease-Suppressive Microbes and Bioprotectants for Aquaculture and Crop Diseases

Objective

MARBLES will use a novel and systematic approach to access and exploit marine microbial biodiversity for sustainable bioprospecting to discover microbial consortia and bioactive molecules for application in aqua- and agriculture and in the clinic. MARBLES' ecology-based bioprospecting strategy will focuses on unique host-microbe interactions in marine environments, including marine sponges, microalgae and fish, which rely on their microbiomes and microbial natural products for disease resistance. Partners’ existing microbial collections and new ones generated during MARBLES will be harnessed for the discovery of novel natural products and synthetic microbial communities. For this, MARBLES will use a systems-wide genomics approach to uncover the bioactive agents in disease-suppressive microbiomes. Also, MARBLES will explore host- and microbe-derived chemicals that elicit production of bioactive compounds, as elicitors to revitalise drug screening. The deliverables will be microbes and consortia and bioactive natural products, their derivatives and elicitors, which can be harnessed to fight infectious diseases in the agrochemical and aquaculture industries and in healthcare.
Besides highly innovative, the approaches will be cost-effective and will offer advantages from both environmental and health perspectives in comparison to existing alternatives. The sustainable production of bioprotectants will increase the effectiveness of fish production - reducing the pressure on harvesting wild fish - and aid the transition of the crop agriculture sector towards bio-based and circular solutions. MARBLES will work closely together with a panel of SMEs and large companies from the EU aquaculture, crop protection biotechnology and health sectors. MARBLES fully complies with the Nagoya and Cartagena Protocols, and aims to make major contributions to the UN sustainable development goals, SDG 2, 3, 12, 13 and 14, as well as to current UN processes (BBNJ, DSI, SynBio)

Call for proposal

H2020-FNR-2020-2
See other projects for this call

Funding Scheme

RIA - Research and Innovation action
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Coordinator

UNIVERSITEIT LEIDEN
Address
Rapenburg 70
2311 EZ Leiden
Netherlands
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 098 620

Participants (13)

ERINN INNOVATION LIMITED
Ireland
EU contribution
€ 469 680
Address
Olympic House Pleasants Street
D08H67X Dublin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
SINTEF AS
Norway
EU contribution
€ 536 375
Address
Strindvegen 4
7034 Trondheim
Activity type
Research Organisations
WAGENINGEN UNIVERSITY
Netherlands
EU contribution
€ 497 795
Address
Droevendaalsesteeg 4
6708 PB Wageningen
Activity type
Higher or Secondary Education Establishments
THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN
United Kingdom
EU contribution
€ 638 088,75
Address
King's College Regent Walk
AB24 3FX Aberdeen
Activity type
Higher or Secondary Education Establishments
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK
Ireland
EU contribution
€ 606 505
Address
Western Road
T12 YN60 Cork
Activity type
Higher or Secondary Education Establishments
NAICONS SRL
Italy
EU contribution
€ 433 928,75
Address
Via Guaragna 3
20147 Saronno Va
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
DANMARKS TEKNISKE UNIVERSITET
Denmark
EU contribution
€ 713 125
Address
Anker Engelundsvej 1 Bygning 101 A
2800 Kgs Lyngby
Activity type
Higher or Secondary Education Establishments
STICHTING NATURALIS BIODIVERSITY CENTER
Netherlands
EU contribution
€ 513 170
Address
Darwinweg 2
2333CR Leiden
Activity type
Research Organisations
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
Switzerland
EU contribution
€ 452 615
Address
Raemistrasse 101
8092 Zuerich
Activity type
Higher or Secondary Education Establishments
FUNDACION CENTRO DE EXCELENCIA EN INVESTIGACION DE MEDICAMENTOS INNOVADORES EN ANDALUCIA
Spain
EU contribution
€ 685 618,75
Address
Avda Del Conocimiento 3
18100 Armilla Granada
Activity type
Research Organisations
FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
Germany
EU contribution
€ 285 750
Address
Hansastrasse 27C
80686 Munchen
Activity type
Research Organisations
EUROPEAN INFRASTRUCTURE OF OPEN SCREENING PLATFORMS FOR CHEMICAL BIOLOGY EUROPEAN RESEARCH INFRASTUCTURE CONSORTIUM (EU-OPENSCREEN ERIC)
Germany
EU contribution
€ 76 250
Address
Robert-rossle-str. 10
13125 Berlin
Activity type
Research Organisations
ABS INTERNATIONAL
Belgium
EU contribution
€ 489 375
Address
Vaartdijkstraat 19D
8200 Bruges
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)