Project description DEENESFRITPL Harnessing marine biodiversity for the discovery of novel bioprotectants Bioprospecting can provide microbiomes and microbial natural products that promote disease resistance by focusing on unique host–microbe interactions in marine sponges, microalgae and fish. The EU-funded MARBLES project will employ an ecology-based bioprospecting strategy to reveal the bioactive agents in disease-suppressive microbiomes and explore host- and microbe-derived chemicals that elicit the production of bioactive compounds. Results will include microbial consortia and bioactive natural products, their derivatives and elicitors, which can be used to combat infectious diseases in the agrochemical and aquaculture industries and in healthcare. In addition, the sustainable production of bioprotectants will enhance fish production, reduce harvesting pressure on wild stocks and facilitate the transition to bio-based and circular solutions. Show the project objective Hide the project objective Objective MARBLES will use a novel and systematic approach to access and exploit marine microbial biodiversity for sustainable bioprospecting to discover microbial consortia and bioactive molecules for application in aqua- and agriculture and in the clinic. MARBLES' ecology-based bioprospecting strategy will focuses on unique host-microbe interactions in marine environments, including marine sponges, microalgae and fish, which rely on their microbiomes and microbial natural products for disease resistance. Partners’ existing microbial collections and new ones generated during MARBLES will be harnessed for the discovery of novel natural products and synthetic microbial communities. For this, MARBLES will use a systems-wide genomics approach to uncover the bioactive agents in disease-suppressive microbiomes. Also, MARBLES will explore host- and microbe-derived chemicals that elicit production of bioactive compounds, as elicitors to revitalise drug screening. The deliverables will be microbes and consortia and bioactive natural products, their derivatives and elicitors, which can be harnessed to fight infectious diseases in the agrochemical and aquaculture industries and in healthcare. Besides highly innovative, the approaches will be cost-effective and will offer advantages from both environmental and health perspectives in comparison to existing alternatives. The sustainable production of bioprotectants will increase the effectiveness of fish production - reducing the pressure on harvesting wild fish - and aid the transition of the crop agriculture sector towards bio-based and circular solutions. MARBLES will work closely together with a panel of SMEs and large companies from the EU aquaculture, crop protection biotechnology and health sectors. MARBLES fully complies with the Nagoya and Cartagena Protocols, and aims to make major contributions to the UN sustainable development goals, SDG 2, 3, 12, 13 and 14, as well as to current UN processes (BBNJ, DSI, SynBio) Fields of science natural sciencesbiological sciencesmarine biologyagricultural sciencesagriculture, forestry, and fisheriesfisheriesagricultural sciencesagriculture, forestry, and fisheriesagriculturenatural sciencesbiological sciencesmicrobiology Programme(s) H2020-EU.3.2. - SOCIETAL CHALLENGES - Food security, sustainable agriculture and forestry, marine, maritime and inland water research, and the bioeconomy Main Programme H2020-EU.3.2.4.1. - Fostering the bio-economy for bio-based industries Topic(s) FNR-11-2020 - Prospecting aquatic and terrestrial natural biological resources for biologically active compounds Call for proposal H2020-FNR-2020 See other projects for this call Sub call H2020-FNR-2020-2 Funding Scheme RIA - Research and Innovation action Coordinator UNIVERSITEIT LEIDEN Net EU contribution € 1 098 620,00 Address Rapenburg 70 2311 EZ Leiden Netherlands See on map Region West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Participants (13) Sort alphabetically Sort by Net EU contribution Expand all Collapse all ERINN INNOVATION LIMITED Ireland Net EU contribution € 469 680,00 Address Olympic house pleasants street D08H67X Dublin See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Ireland Eastern and Midland Dublin Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 SINTEF AS Norway Net EU contribution € 536 375,00 Address Strindvegen 4 7034 Trondheim See on map Region Norge Trøndelag Trøndelag Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 WAGENINGEN UNIVERSITY Netherlands Net EU contribution € 497 795,00 Address Droevendaalsesteeg 4 6708 PB Wageningen See on map Region Oost-Nederland Gelderland Veluwe Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITY OF ABERDEEN United Kingdom Net EU contribution € 638 088,75 Address King's college regent walk AB24 3FX Aberdeen See on map Region Scotland North Eastern Scotland Aberdeen City and Aberdeenshire Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK Ireland Net EU contribution € 606 505,00 Address Western road T12 YN60 Cork See on map Region Ireland Southern South-East Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 NAICONS SRL Italy Net EU contribution € 433 928,75 Address Via guaragna 3 20147 Saronno va See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Nord-Ovest Lombardia Milano Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 DANMARKS TEKNISKE UNIVERSITET Denmark Net EU contribution € 713 125,00 Address Anker engelunds vej 101 2800 Kongens lyngby See on map Region Danmark Hovedstaden Københavns omegn Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 STICHTING NATURALIS BIODIVERSITY CENTER Netherlands Net EU contribution € 513 170,00 Address Darwinweg 2 2333 CR Leiden See on map Region West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH Switzerland Net EU contribution € 452 615,00 Address Raemistrasse 101 8092 Zuerich See on map Region Schweiz/Suisse/Svizzera Zürich Zürich Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 FUNDACION CENTRO DE EXCELENCIA EN INVESTIGACION DE MEDICAMENTOS INNOVADORES EN ANDALUCIA Spain Net EU contribution € 685 618,75 Address Avda del conocimiento 3 18100 Armilla granada See on map Region Sur Andalucía Granada Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV Germany Net EU contribution € 285 750,00 Address Hansastrasse 27c 80686 Munchen See on map Region Bayern Oberbayern München, Kreisfreie Stadt Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 EUROPEAN INFRASTRUCTURE OF OPEN SCREENING PLATFORMS FOR CHEMICAL BIOLOGY EUROPEAN RESEARCH INFRASTUCTURE CONSORTIUM (EU-OPENSCREEN ERIC) Germany Net EU contribution € 76 250,00 Address Robert-rossle-str. 10 13125 Berlin See on map Region Berlin Berlin Berlin Activity type Research Organisations Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 ABS-INTERNATIONAL Belgium Net EU contribution € 489 375,00 Address Kortrijksesteenweg 127 9830 Sint martens latem See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00
