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REpurposing lung Surfactant Protein B for Inhalation therapy with RNA therapeutics

Project description

Nanocarriers for RNA delivery in the lung

RNA therapeutics have the potential to revolutionise medicine, but efficient nanotechnology-based strategies are required for their delivery inside cells. The EU-funded RESPIRNA project proposes to repurpose the lung surfactant protein B (SP-B), a key component of pulmonary surfactant, for intracellular RNA delivery. Researchers will investigate the mechanism of action of SP-B and optimise its utilisation for RNA therapeutics. Deliverables will aid the rational design of the next generation of nanocarrier-based RNA formulations capable of crossing cell membranes. Long-term, this will address the unmet medical need for the treatment of many lung diseases.

Host institution

UNIVERSITEIT GENT
Net EU contribution
€ 1 985 828,00
Address
Sint Pietersnieuwstraat 25
9000 Gent
Belgium

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Region
Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Beneficiaries (1)

UNIVERSITEIT GENT
Belgium
Net EU contribution
€ 1 985 828,00
Address
Sint Pietersnieuwstraat 25
9000 Gent

See on map

Region
Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00