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Monoclonal Antibodies against 2019-New Coronavirus

Resultado final

Communication and dissemination plan

Thisocument defines the direction of the project Communication, including the priorities, the target groups, messages, tools and resources for Communication and dissemination, as well as the organisation of both internal and external Communication by the consortium.

Publicaciones

A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies

Autores: Chunyan Wang, Rien van Haperen, Javier Gutiérrez-Álvarez, Wentao Li, Nisreen M. A. Okba, Irina Albulescu, Ivy Widjaja, Brenda van Dieren, Raul Fernandez-Delgado, Isabel Sola, Daniel L. Hurdiss, Olalekan Daramola, Frank Grosveld, Frank J. M. van Kuppeveld, Bart L. Haagmans, Luis Enjuanes, Dubravka Drabek, Berend-Jan Bosch
Publicado en: Nature Communications, Issue 12/1, 2021, Page(s) 1-15, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-021-21968-w

SARS-CoV-2 Omicron variant causes mild pathology in the upper and lower respiratory tract of hamsters

Autores: Federico Armando, Georg Beythien, Franziska K. Kaiser, Lisa Allnoch, Laura Heydemann, Malgorzata Rosiak, Svenja Becker, Mariana Gonzalez-Hernandez, Mart M. Lamers, Bart L. Haagmans, Kate Guilfoyle, Geert van Amerongen, Malgorzata Ciurkiewicz, Albert D.M.E. Osterhaus & Wolfgang Baumgärtner
Publicado en: Nature Communications, 2022, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-022-31200-y

Genetically Engineered Live-Attenuated Middle East Respiratory Syndrome Coronavirus Viruses Confer Full Protection against Lethal Infection

Autores: Javier Gutiérrez-Álvarez, José M. Honrubia, Raúl Fernández-Delgado, Li Wang, Carlos Castaño-Rodríguez, Sonia Zúñiga, Isabel Sola, Luis Enjuanes
Publicado en: mBio, Issue 12/2, 2021, ISSN 2150-7511
Editor: mBio
DOI: 10.1128/mbio.00103-21

Middle East respiratory syndrome coronavirus vaccine based on a propagation-defective RNA replicon elicited sterilizing immunity in mice

Autores: J Gutiérrez-Álvarez 1, J M Honrubia 1, A Sanz-Bravo 1, E González-Miranda 1, R Fernández-Delgado 1, M T Rejas 2, S Zúñiga 1, I Sola 1, L Enjuanes 3
Publicado en: Proc Natl Acad Sci USA, Issue 10916490, 2021, ISSN 1091-6490
Editor: Proc Natl Acad Sci USA
DOI: 10.1073/pnas.2111075118

An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern

Autores: Wenjuan Du 1, Daniel L Hurdiss 1, Dubravka Drabek 2 3, Anna Z Mykytyn 4, Franziska K Kaiser 5, Mariana González-Hernández 5, Diego Muñoz-Santos 6, Mart M Lamers 4, Rien van Haperen 2 3, Wentao Li 1, Ieva Drulyte 7, Chunyan Wang 1, Isabel Sola 6, Federico Armando 8, Georg Beythien 8, Malgorzata Ciurkiewicz 8, Wolfgang Baumgärtner 8, Kate Guilfoyle 9, Tony Smits 1, Joline van der Lee 1, Frank J
Publicado en: Sci Immunol., Issue 24709468, 2022, ISSN 2470-9468
Editor: Sci Immunol.
DOI: 10.1126/sciimmunol.abp9312

Nature of viruses and pandemics: Coronaviruses

Autores: Luis Enjuanes 1, Isabel Sola 1, Sonia Zúñiga 1, José M Honrubia 1, Melissa Bello-Pérez 1, Alejandro Sanz-Bravo 1, Ezequiel González-Miranda 1, Jesús Hurtado-Tamayo 1, Ricardo Requena-Platek 1, Li Wang 1, Diego Muñoz-Santos 1, Carlos M Sánchez 1, Ana Esteban 1, Jorge Ripoll-Gómez 1
Publicado en: Curr Res Immunol., Issue 25902555, 2022, ISSN 2590-2555
Editor: Curr Res Immunol.
DOI: 10.1016/j.crimmu.2022.08.003

MOV10 Helicase Interacts with Coronavirus Nucleocapsid Protein and Has Antiviral Activity

Autores: Li Wang 1, Isabel Sola 1, Luis Enjuanes 1, Sonia Zuñiga 1
Publicado en: mBio, Issue 21612129, 2021, ISSN 2161-2129
Editor: American Society for Microbiology
DOI: 10.1128/mbio.01316-21

Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19

Autores: "Lok-Yin Roy Wong # 1, Jian Zheng # 1, Kevin Wilhelmsen 2, Kun Li 3, Miguel E Ortiz 3, Nicholas J Schnicker 4, Andrew Thurman 5, Alejandro A Pezzulo 5, Peter J Szachowicz 5, Pengfei Li 1, Ruangang Pan 1, Klaus Klumpp 2, Fred Aswad 2, Justin Rebo 2, Shuh Narumiya 6, Makoto Murakami 7, Sonia Zuniga 8, Isabel Sola 8, Luis Enjuanes 8, David K Meyerholz 9, Kristen Fortney 2, Paul B McCray Jr 10 11, Stan"
Publicado en: Nature, Issue 14764687, 2022, ISSN 1476-4687
Editor: Nature
DOI: 10.1038/s41586-022-04630-3

Contribution of Host miRNA-223-3p to SARS-CoV-Induced Lung Inflammatory Pathology

Autores: Lucía Morales 1, Juan Carlos Oliveros 2, Luis Enjuanes 1, Isabel Sola 1
Publicado en: mBio, Issue 21612129, 2022, ISSN 2161-2129
Editor: American Society for Microbiology
DOI: 10.1128/mbio.03135-21

SARS-CoV-2 neutralizing human antibodies protect against lower respiratory tract disease in a hamster model.

Autores: Haagmans, Bart L; Noack, Danny; Okba, Nisreen M A; Li, Wentao; Wang, Chunyan; Bestebroer, Theo; de Vries, Rory; Herfst, Sander; de Meulder, Dennis; Verveer, Elwin; van Run, Peter; Lamers, Mart M; Rijnders, Bart; Rokx, Casper; van Kuppeveld, Frank; Grosveld, Frank; Drabek, Dubravka; GeurtsvanKessel, Corine; Koopmans, Marion; Bosch, Berend Jan; Kuiken, Thijs; Rockx, Barry; dI&I I&I-1; Virologie
Publicado en: urn:issn:0022-1899, Issue 15536203, 2021, ISSN 1553-6203
Editor: Science Publications
DOI: 10.1093/infdis/jiab289

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