Monoclonal Antibodies against 2019-New Coronavirus

Rezultaty

Thisocument defines the direction of the project Communication, including the priorities, the target groups, messages, tools and resources for Communication and dissemination, as well as the organisation of both internal and external Communication by the consortium.

Publikacje

A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies

Autorzy: Chunyan Wang, Rien van Haperen, Javier Gutiérrez-Álvarez, Wentao Li, Nisreen M. A. Okba, Irina Albulescu, Ivy Widjaja, Brenda van Dieren, Raul Fernandez-Delgado, Isabel Sola, Daniel L. Hurdiss, Olalekan Daramola, Frank Grosveld, Frank J. M. van Kuppeveld, Bart L. Haagmans, Luis Enjuanes, Dubravka Drabek, Berend-Jan Bosch
Opublikowane w: Nature Communications, Numer 12/1, 2021, Strona(/y) 1-15, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-021-21968-w

SARS-CoV-2 Omicron variant causes mild pathology in the upper and lower respiratory tract of hamsters

Autorzy: Federico Armando, Georg Beythien, Franziska K. Kaiser, Lisa Allnoch, Laura Heydemann, Malgorzata Rosiak, Svenja Becker, Mariana Gonzalez-Hernandez, Mart M. Lamers, Bart L. Haagmans, Kate Guilfoyle, Geert van Amerongen, Malgorzata Ciurkiewicz, Albert D.M.E. Osterhaus & Wolfgang Baumgärtner
Opublikowane w: Nature Communications, 2022, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-022-31200-y

Genetically Engineered Live-Attenuated Middle East Respiratory Syndrome Coronavirus Viruses Confer Full Protection against Lethal Infection

Autorzy: Javier Gutiérrez-Álvarez, José M. Honrubia, Raúl Fernández-Delgado, Li Wang, Carlos Castaño-Rodríguez, Sonia Zúñiga, Isabel Sola, Luis Enjuanes
Opublikowane w: mBio, Numer 12/2, 2021, ISSN 2150-7511
Wydawca: mBio
DOI: 10.1128/mbio.00103-21

Middle East respiratory syndrome coronavirus vaccine based on a propagation-defective RNA replicon elicited sterilizing immunity in mice

Autorzy: J Gutiérrez-Álvarez 1, J M Honrubia 1, A Sanz-Bravo 1, E González-Miranda 1, R Fernández-Delgado 1, M T Rejas 2, S Zúñiga 1, I Sola 1, L Enjuanes 3
Opublikowane w: Proc Natl Acad Sci USA, Numer 10916490, 2021, ISSN 1091-6490
Wydawca: Proc Natl Acad Sci USA
DOI: 10.1073/pnas.2111075118

An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern

Autorzy: Wenjuan Du 1, Daniel L Hurdiss 1, Dubravka Drabek 2 3, Anna Z Mykytyn 4, Franziska K Kaiser 5, Mariana González-Hernández 5, Diego Muñoz-Santos 6, Mart M Lamers 4, Rien van Haperen 2 3, Wentao Li 1, Ieva Drulyte 7, Chunyan Wang 1, Isabel Sola 6, Federico Armando 8, Georg Beythien 8, Malgorzata Ciurkiewicz 8, Wolfgang Baumgärtner 8, Kate Guilfoyle 9, Tony Smits 1, Joline van der Lee 1, Frank J
Opublikowane w: Sci Immunol., Numer 24709468, 2022, ISSN 2470-9468
Wydawca: Sci Immunol.
DOI: 10.1126/sciimmunol.abp9312

Nature of viruses and pandemics: Coronaviruses

Autorzy: Luis Enjuanes 1, Isabel Sola 1, Sonia Zúñiga 1, José M Honrubia 1, Melissa Bello-Pérez 1, Alejandro Sanz-Bravo 1, Ezequiel González-Miranda 1, Jesús Hurtado-Tamayo 1, Ricardo Requena-Platek 1, Li Wang 1, Diego Muñoz-Santos 1, Carlos M Sánchez 1, Ana Esteban 1, Jorge Ripoll-Gómez 1
Opublikowane w: Curr Res Immunol., Numer 25902555, 2022, ISSN 2590-2555
Wydawca: Curr Res Immunol.
DOI: 10.1016/j.crimmu.2022.08.003

MOV10 Helicase Interacts with Coronavirus Nucleocapsid Protein and Has Antiviral Activity

Autorzy: Li Wang 1, Isabel Sola 1, Luis Enjuanes 1, Sonia Zuñiga 1
Opublikowane w: mBio, Numer 21612129, 2021, ISSN 2161-2129
Wydawca: American Society for Microbiology
DOI: 10.1128/mbio.01316-21

Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19

Autorzy: "Lok-Yin Roy Wong # 1, Jian Zheng # 1, Kevin Wilhelmsen 2, Kun Li 3, Miguel E Ortiz 3, Nicholas J Schnicker 4, Andrew Thurman 5, Alejandro A Pezzulo 5, Peter J Szachowicz 5, Pengfei Li 1, Ruangang Pan 1, Klaus Klumpp 2, Fred Aswad 2, Justin Rebo 2, Shuh Narumiya 6, Makoto Murakami 7, Sonia Zuniga 8, Isabel Sola 8, Luis Enjuanes 8, David K Meyerholz 9, Kristen Fortney 2, Paul B McCray Jr 10 11, Stan"
Opublikowane w: Nature, Numer 14764687, 2022, ISSN 1476-4687
Wydawca: Nature
DOI: 10.1038/s41586-022-04630-3

Contribution of Host miRNA-223-3p to SARS-CoV-Induced Lung Inflammatory Pathology

Autorzy: Lucía Morales 1, Juan Carlos Oliveros 2, Luis Enjuanes 1, Isabel Sola 1
Opublikowane w: mBio, Numer 21612129, 2022, ISSN 2161-2129
Wydawca: American Society for Microbiology
DOI: 10.1128/mbio.03135-21

SARS-CoV-2 neutralizing human antibodies protect against lower respiratory tract disease in a hamster model.

Autorzy: Haagmans, Bart L; Noack, Danny; Okba, Nisreen M A; Li, Wentao; Wang, Chunyan; Bestebroer, Theo; de Vries, Rory; Herfst, Sander; de Meulder, Dennis; Verveer, Elwin; van Run, Peter; Lamers, Mart M; Rijnders, Bart; Rokx, Casper; van Kuppeveld, Frank; Grosveld, Frank; Drabek, Dubravka; GeurtsvanKessel, Corine; Koopmans, Marion; Bosch, Berend Jan; Kuiken, Thijs; Rockx, Barry; dI&I I&I-1; Virologie
Opublikowane w: urn:issn:0022-1899, Numer 15536203, 2021, ISSN 1553-6203
Wydawca: Science Publications
DOI: 10.1093/infdis/jiab289

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