MOlecular-Scale Biophysics Research Infrastructure

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Dissemination of novel methodologies via website

Dissemination of novel methodologies via websiteDeliverable to be submitted in M12 M24 and M48

Operational proposal system based on ARIA cloud service
Driving licence specifications and test materials at Operator level
MOSBRI website

Report on joint events organized with ARBRE and EBSA

Report on joint events organized with ARBRE and EBSADeliverable to be submitted in M18 M30 and M42

Analysis of the mapping of the needs for data standards/formats

Analysis of the mapping of the needs for data standardsformats

Established reference calibration samples
Analysis of the mapping of the needs for repository/database

Analysis of the mapping of the needs for repositorydatabase

Report on joint events organized with INSTRUCT

Report on joint events organized with INSTRUCTDeliverable to be submitted in M18 M30 and M42

Setting-up of a TNA moderator panel and of a TNA reviewer panel

Publications

Multidimensional Decomposition and Ensemble Modeling of Histatin 1 and Its Siblings: Detailing Structure and Biological Function Using an Integrative Approach

Auteurs: Oskar Svensson, Yuri Gerelli, Marie Skepö
Publié dans: Journal of Chemical Information and Modeling, Numéro 65, 2025, Page(s) 7089-7101, ISSN 1549-9596
Éditeur: American Chemical Society
DOI: 10.1021/acs.jcim.5c00854

Cubosome lipid nanocarriers for delivery of ultra-short antimicrobial peptides

Auteurs: Biserka Lakic, Chia Beh, Sampa Sarkar, Sue-Lyn Yap, Priscila Cardoso, Celine Valery, Andrew Hung, Nykola C. Jones, Søren Vrønning Hoffmann, Ewan W. Blanch, Brendan Dyett, Charlotte E. Conn
Publié dans: Journal of Colloid and Interface Science, Numéro 677, 2024, Page(s) 1080-1097, ISSN 0021-9797
Éditeur: Academic Press
DOI: 10.1016/j.jcis.2024.07.232

Interaction of a Histidine-Rich Antimicrobial Saliva Peptide with Model Cell Membranes: The Role of Histidines

Auteurs: Skog, A. E., Corucci, G., Tully, M. D., Fragneto, G., Gerelli, Y., Skepö, M.
Publié dans: Langmuir, Numéro 39, 2023, Page(s) 7694, ISSN 1520-5827
Éditeur: ACS Publications
DOI: 10.1021/acs.langmuir.3c00498

Protein secondary structure determined from independent and integrated infra-red absorbance and circular dichroism data using the algorithm SELCON

Auteurs: Søren Vrønning Hoffmann, Nykola C. Jones, Alison Rodger
Publié dans: QRB Discovery, Numéro 6, 2025, ISSN 2633-2892
Éditeur: Cambridge University Press (CUP)
DOI: 10.1017/qrd.2025.4

Impact of Cellular Crowding on Protein Structural Dynamics Investigated by EPR Spectroscopy

Auteurs: Annalisa Pierro, Alessio Bonucci, Axel Magalon, Valérie Belle, Elisabetta Mileo
Publié dans: Chemical Reviews, Numéro 124, 2024, Page(s) 9873-9898, ISSN 0009-2665
Éditeur: American Chemical Society
DOI: 10.1021/acs.chemrev.3c00951

Molecular Biophysics Database (MBDB) makes raw measurements findable and reusable

Auteurs: Emil Dandanell Agerschou, Terezie Prchalová, Miroslav Šimek, Michal Malý, Jan Stránský, Michal Strnad, Andrea Santisteban-Veiga, Mark A. Williams, Juan Sabín, Jan Dohnálek
Publié dans: European Biophysics Journal, 2025, ISSN 0175-7571
Éditeur: Springer Verlag
DOI: 10.1007/s00249-025-01789-1

Plant vs Dairy protein stabilised cappuccino foams: how protein and hydrocolloid conformational changes affect foam stability

Auteurs: Silvana Wüest, Johann Buczkowski, Nykola C. Jones, Søren Vrønning Hoffmann, Peter Fischer, Tim J. Wooster
Publié dans: Food Hydrocolloids, Numéro 169, 2025, Page(s) 111621, ISSN 0268-005X
Éditeur: Elsevier BV
DOI: 10.1016/j.foodhyd.2025.111621

DNA methylation enhances cooperative disentanglement by the Hfq nucleoid-associated protein

Auteurs: Frank Wien, Nykola C. Jones, Søren Vrønning Hoffmann, Véronique Arluison
Publié dans: European Biophysics Journal, 2025, ISSN 0175-7571
Éditeur: Springer Verlag
DOI: 10.1007/s00249-025-01800-9

Temoneira-1 beta-lactamase is not a metalloenzyme, but its native metal ion binding sites allow for purification by immobilized metal ion affinity chromatography

Auteurs: Nafaee, Z.H., Hunyadi-Gulyas, E., Gyurcsik, B.
Publié dans: Protein Expression and Purification, 2023, ISSN 1046-5928
Éditeur: Academic Press
DOI: 10.1016/j.pep.2022.106169

Structure and conformational variability of the HER2-trastuzumab-pertuzumab complex

Auteurs: Ruedas, R., Vuillemot, R., Tubiana, T., Winter, J. M., Pieri, L., Arteni, A.-A., Samson, C., Jonic, S., Mathieu, M., Bressanelli, S.
Publié dans: Journal of Structural Biology, 2024, ISSN 1047-8477
Éditeur: Academic Press
DOI: 10.1016/j.jsb.2024.108095

Expanding the Diversity of Nitroxide‐Based Paramagnetic Probes Conjugated to Non‐Canonical Amino Acids for Sdsl‐Epr Applications

Auteurs: Maxime Bizet, Áron Balázsi, Frédéric Biaso, Deborah Byrne, Emilien Etienne, Bruno Guigliarelli, Philippe Urban, Pierre Dorlet, Gilles Truan, Guillaume Gerbaud, Tamás Kálai, Marlène Martinho
Publié dans: ChemBioChem, Numéro 26, 2025, ISSN 1439-4227
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.202500064

The phosphodiesterase RmcA contributes to the adaptation of Pseudomonas putida to l-arginine

Auteurs: Scribani-Rossi C, Molina-Henares MA, Angeli S, Cutruzzolà F, Paiardini A, Espinosa-Urgel M, Rinaldo S.
Publié dans: FEMS Microbiology Letters, Numéro Volume 370, 2023, ISSN 1574-6968
Éditeur: Oxford university press
DOI: 10.1093/femsle/fnad077

Electrochemical Kinetics Support a Second Coordination Sphere Mechanism in Metal-Based Formate Dehydrogenase

Auteurs: Marta Meneghello, Alexandre Uzel, Marianne Broc, Rita R. Manuel, Axel Magalon, Christophe Léger, Inês A. C. Pereira, Anne Walburger, Vincent Fourmond
Publié dans: Angewandte Chemie - International edition, Numéro 134, e202299999, 2022, ISSN 1521-3773
Éditeur: Wiley-VCH GmbH
DOI: 10.1002/anie.202212224

ProteinLIPs: a web server for identifying highly polar and poorly packed interfaces in proteins

Auteurs: Helena García-Cebollada, Alfonso López, Vladimir E Angarica, Juan José Galano-Frutos, Javier Sancho
Publié dans: Bioinformatics, Numéro 41, 2025, ISSN 1367-4803
Éditeur: Oxford University Press
DOI: 10.1093/bioinformatics/btaf499

Visualizing Molecular Dynamics by High-Speed Atomic Force Microscopy

Auteurs: van Ewijk, C., Maity, S., Roos, W.H.
Publié dans: Single Molecule Analysis . Methods in Molecular Biology, 2023, ISSN 1064-3745
Éditeur: Humana Press, Inc.
DOI: 10.1007/978-1-0716-3377-9_17

Interactions and Insertion of Escherichia coli Hfq into Outer Membrane Vesicles as Revealed by Infrared and Orientated Circular Dichroism Spectroscopies

Auteurs: Turbant, F., Waeytens, J., Blache, A., Esnouf, E., Raussens, V., Wegrzyn, G., Achouak, W., Wien, F., Arluison, V.
Publié dans: International Journal of Molecular Sciences, Numéro 24(14), 11424, 2023, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms241411424

Despite the odds: formation of the SARS-CoV-2 methylation complex

Auteurs: Matsuda, A., Plewka, J., Rawski, M., Mourão, A., Zajko, W., Siebenmorgen, T., Kresik, L., Lis, K., Jones, A. N., Pachota, M., Karim, A., Hartman, K., Nirwal, S., Sonani, R., Chykunova,Y., Minia, I., Mak, P., Landthaler, M., Nowotny, M., Dubin, G., Sattler, M., Suder, P., Popowicz, G. M., Pyrć, K., Czarna, A.
Publié dans: Nucleic Acids Research, 2024, ISSN 1362-4962
Éditeur: Oxford university press
DOI: 10.1093/nar/gkae165

Lateral membrane organization as target of an antimicrobial peptidomimetic compound

Auteurs: Melcrova, A., Maity, S., Melcr, J., de Kok, N.A.W., Gabler, M., van der Eyden, J., Stensen, W., Svendsen, J.S.M., Driessen, A.J.M., Marrink, S.J., Roos, W.H.
Publié dans: Nature Communications, Numéro 14(1) ar4038, 2023, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-023-39726-5

Influence of the enzymatic treatment and pH on the interfacial and emulsifying properties of sunflower and olive protein hydrolysates

Auteurs: Pérez-Gálvez, R., Maldonado-Valderrama, J., Jones, N. C., Hoffmann, S. V., Guadix, E., García-Moreno, P. J.
Publié dans: Food Hydrocolloids, Numéro 154 ar110135, 2024, ISSN 0268-005X
Éditeur: Elsevier BV
DOI: 10.1016/j.foodhyd.2024.110135

Modifying recombinant purple acid phosphatase using computational design

Auteurs: Aishwarya Venkatramani, Montader Ali, Olga Predeina, Jennifer C. Molloy, Pietro Sormanni, Elizabeth A. H. Hall
Publié dans: European Biophysics Journal, 2025, ISSN 0175-7571
Éditeur: Springer Verlag
DOI: 10.1007/s00249-025-01779-3

13th EBSA congress, July 24–28, 2021, Vienna, Austria

Auteurs: 13th EBSA congress
Publié dans: European Biophysics Journal, Numéro 50/S1, 2021, Page(s) 1-226, ISSN 0175-7571
Éditeur: Springer Verlag
DOI: 10.1007/s00249-021-01558-w

Protein Microarrays for High Throughput Hydrogen/Deuterium Exchange Monitored by FTIR Imaging

Auteurs: Joëlle De Meutter, Erik Goormaghtigh
Publié dans: International Journal of Molecular Sciences, Numéro 25, 2025, Page(s) 9989, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms25189989

ATR-FTIR Biosensors for Antibody Detection and Analysis

Auteurs: Suys, O., Derenne, A., Goormaghtigh, E.
Publié dans: International Journal of Molecular Sciences, Numéro 23(19), 2022, Page(s) 11895, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms231911895

Spectroscopic insights into the mechanism of anammox hydrazine synthase

Auteurs: Wouter Versantvoort, Rainer Hienerwadel, Christina Ferousi, Pieter van der Velden, Catherine Berthomieu, Laura van Niftrik, Frauke Baymann
Publié dans: Journal of Biological Chemistry, Numéro 301, 2025, Page(s) 110771, ISSN 0021-9258
Éditeur: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.jbc.2025.110771

Biochemical characterization of L-asparaginase isoforms from Rhizobium etli—the boosting effect of zinc

Auteurs: Sliwiak, J., Worsztynowicz, P., Pokrywka, K., Loch, J. I., Grzechowiak, M., Jaskolski, M.
Publié dans: Frontiers in Chemistry, 2024, ISSN 2296-2646
Éditeur: Frontiers Media S.A
DOI: 10.3389/fchem.2024.1373312

Protein Structural Denaturation Evaluated by MCR-ALS of Protein Microarray FTIR Spectra

Auteurs: De Meutter, J., Goormaghtigh, E.
Publié dans: Analytical Chemistry, Numéro 93(40), 2021, Page(s) 13441-13449, ISSN 1520-6882
Éditeur: American Chemical Society publications
DOI: 10.1021/acs.analchem.1c01416

Molecular insights into RmcA-mediated c-di-GMP consumption: Linking redox potential to biofilm morphogenesis in Pseudomonas aeruginosa

Auteurs: Scribani Rossi, C., Eckartt, K., Scarchilli, E., Angeli, S., Price-Whelan, A., Di Matteo, A., Chevreuil, M., Raynal, B., Arcovito, A., Giacon, N., Fiorentino, F., Rotili, D.,
Publié dans: Microbiological Research, Numéro Volume 277, 127498, 2023, ISSN 1618-0623
Éditeur: Elsevier
DOI: 10.1016/j.micres.2023.127498

In Vitro Cell Model Investigation of Alpha-Synuclein Aggregate Morphology Using Spectroscopic Imaging

Auteurs: Priyanka Swaminathan, Therése Klingstedt, Vasileios Theologidis, Hjalte Gram, Johan Larsson, Lars Hagen, Nina B. Liabakk, Odrun A. Gederaas, Per Hammarström, K. Peter R. Nilsson, Nathalie Van Den Berge, Mikael Lindgren
Publié dans: International Journal of Molecular Sciences, Numéro 25, 2025, Page(s) 12458, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms252212458

Modulation of conformational features and oligomerization of MMACHC by cobalamin variants: impact of the R161Q mutation in cblC disease

Auteurs: Lisa Longo, Maria Assunta Costa, Rita Carrotta, Maria Rosalia Mangione, Vincenzo Martorana, Marco Tutone, Maria Grazia Ortore, Paula M. Garcia-Franco, Sonia Vega, Adrian Velazquez-Campoy, Rosa Passantino, Silvia Vilasi
Publié dans: European Biophysics Journal, 2025, ISSN 0175-7571
Éditeur: Springer Verlag
DOI: 10.1007/s00249-025-01777-5

Merging multi-omics with proteome integral solubility alteration unveils antibiotic mode of action

Auteurs: Ritwik Maity, Xuepei Zhang, Francesca Romana Liberati, Chiara Scribani Rossi, Francesca Cutruzzolá, Serena Rinaldo, Massimiliano Gaetani, José Antonio Aínsa, Javier Sancho
Publié dans: eLife, Numéro 13, 2024, ISSN 2050-084X
Éditeur: eLife Sciences Publications
DOI: 10.7554/elife.96343.3

Synthesis of 3,4-Disubstituted Pyrroline Nitroxides Containing Diphenylphosphane or Diphenylphosphane Oxide Substituents

Auteurs: Balázsi, A., Bognár, B., Jeko, J., Kálai, T.
Publié dans: SynOpen, 2024, ISSN 2509-9396
Éditeur: Thieme
DOI: 10.1055/a-2264-8302

ChiraKit: an online tool for the analysis of circular dichroism spectroscopy data

Auteurs: Osvaldo Burastero, Nykola C Jones, Lucas A Defelipe, Uroš Zavrtanik, San Hadži, Søren Vrønning Hoffmann, Maria M Garcia-Alai
Publié dans: Nucleic Acids Research, Numéro 53, 2025, Page(s) W158-W168, ISSN 0305-1048
Éditeur: Oxford University Press
DOI: 10.1093/nar/gkaf350

Contact-free characterization of nuclear mechanics using correlative Brillouin-Raman Micro-Spectroscopy in living cells

Auteurs: S. Kerdegari, A.A. Passeri, F. Morena, G. Ciccone, V. Bazzurro, P. Canepa, A. Lagomarsino, S. Martino, M. Mattarelli, M. Vassalli, A. Diaspro, S. Caponi, C. Canale
Publié dans: Acta Biomaterialia, Numéro 198, 2025, Page(s) 291-301, ISSN 1742-7061
Éditeur: Elsevier BV
DOI: 10.1016/j.actbio.2025.04.009

Raynals, an online tool for the analysis of dynamic light scattering.

Auteurs: Burastero, O., Draper-Barr, G., Raynal, B., Chevreuil, M., England, P., Garcia-Alai, M.
Publié dans: Acta Crystallographica Section D, Numéro 79, 2023, Page(s) p673–683, ISSN 2059-7983
Éditeur: IUCr journals
DOI: 10.1107/s2059798323004862

Exploring the Metabolic Response of Pseudomonas putida to L-arginine

Auteurs: Scribani-Rossi, C., Molina-Henares, M. A., Espinosa-Urgel, M., Rinaldo, S.
Publié dans: Advances in Experimental Medicine and Biology, 2024, ISSN 0065-2598
Éditeur: Kluwer Academic/Plenum Publishers
DOI: 10.1007/5584_2024_797

Membrane-Active Antibiotics Affect Domains in Bacterial Membranes as the First Step of Their Activity

Auteurs: Adéla Melcrová, Christiaan Klein, Wouter H. Roos
Publié dans: Nano Letters, Numéro 24, 2024, Page(s) 11800-11807, ISSN 1530-6984
Éditeur: American Chemical Society
DOI: 10.1021/acs.nanolett.4c01873

Limited high-throughput screening compatibility of the phenuivirus cap-binding domain

Auteurs: Scherf, J., Vogel, D., Gul, S., Reinshagen, J., Gribbon, P., Rosenthal, M.
Publié dans: Scientific Reports, Numéro 13, 2023, Page(s) 22820, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-023-50158-5

Use of emulsifying plant protein hydrolysates from winery, whiskey and brewery by-products for the development of echium oil delivery emulsions

Auteurs: Mariana Sisconeto Bisinotto, Inar Castro, Julia Maldonado-Valderrama, Nykola C. Jones, Teresa del Castillo-Santaella, Søren Vrønning Hoffmann, Emilia M. Guadix, Pedro J. García-Moreno
Publié dans: International Journal of Biological Macromolecules, Numéro 308, 2025, Page(s) 142736, ISSN 0141-8130
Éditeur: Elsevier BV
DOI: 10.1016/j.ijbiomac.2025.142736

SidF, a dual substrate N5-acetyl-N5-hydroxy-L-ornithine transacetylase involved in Aspergillus fumigatus siderophore biosynthesis

Auteurs: Thanalai Poonsiri, Jan Stransky, Nicola Demitri, Hubertus Haas, Michele Cianci, Stefano Benini
Publié dans: Journal of Structural Biology: X, Numéro 11, 2025, Page(s) 100119, ISSN 2590-1524
Éditeur: Elsevier BV
DOI: 10.1016/j.yjsbx.2024.100119

Guidelines for the Simulations of Nitroxide X-Band cw EPR Spectra from Site-Directed Spin Labeling Experiments Using SimLabel

Auteurs: Etienne, E., Pierro, A., Tamburrini, K. C., Bonucci, A., Mileo, E., Martinho, M., Belle, V.
Publié dans: Molecules, Numéro 28, 2023, Page(s) 1348, ISSN 1420-3049
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules28031348

Effect of Cholesterol on Biomimetic Membrane Curvature and Coronavirus Fusion Peptide Encapsulation

Auteurs: Milogrodzka, I., Pham, D.T.N., Sama, G.R., Samadian, H., Zhai, J.L., de Campo, L., Kirby, N.M., Scott, T.F., Holl, M.M.B., van’t Hag, L.
Publié dans: ACS Nano, Numéro 17 (9), 2023, Page(s) 8598-8612, ISSN 1936-0851
Éditeur: American Chemical Society
DOI: 10.1021/acsnano.3c01095

Direct Observation of Secondary Nucleation in Huntingtin Amyloid Formation by High-Speed Atomic Force Microscopy

Auteurs: Chris van Ewijk, Greeshma Jain, Yari K. Knelissen, Sourav Maity, Patrick C. A. van der Wel, Wouter H. Roos
Publié dans: Journal of the American Chemical Society, Numéro 147, 2025, Page(s) 21973-21984, ISSN 0002-7863
Éditeur: American Chemical Society
DOI: 10.1021/jacs.5c05571

The Fluorescent Amyloid Ligand X34 Binding to Transthyretin (TTR) Tetramer and Fibrils: FRET and Binding Constants of a Sequential Two‐step Process

Auteurs: Marikken Sundnes, Priyanka Swaminathan, Mikael Lindgren, Ganesh Mohite, Ebba Hellstrand, Sofie Nyström, Per Hammarström
Publié dans: ChemPhotoChem, Numéro 9, 2025, ISSN 2367-0932
Éditeur: Wiley
DOI: 10.1002/cptc.202400249

The cytoplasmic tail of myelin protein zero induces morphological changes in lipid membranes

Auteurs: Oda C. Krokengen, Christine Touma, Anna Mularski, Aleksi Sutinen, Ryan Dunkel, Marie Ytterdal, Arne Raasakka, Haydyn D.T. Mertens, Adam Cohen Simonsen, Petri Kursula
Publié dans: Biochimica et Biophysica Acta (BBA) - Biomembranes, Numéro 1866, 2025, Page(s) 184368, ISSN 0005-2736
Éditeur: Elsevier BV
DOI: 10.1016/j.bbamem.2024.184368

In-cell investigation of the conformational landscape of the GTPase UreG by SDSL-EPR

Auteurs: Pierro, A., Tamburrini, K.C., Leguenno, H., Gerbaud, G., Etienne, E., Guigliarelli, B., Belle, V., Zambelli, B., Mileo, E.
Publié dans: iScience, Numéro 26(10), 2023, Page(s) 107855, ISSN 2589-0042
Éditeur: cell press
DOI: 10.1016/j.isci.2023.107855

Analysis of the Structure of 14 Therapeutic Antibodies Using Circular Dichroism Spectroscopy

Auteurs: Maria G. Bruque, Alison Rodger, Søren Vrønning Hoffmann, Nykola C. Jones, Jean Aucamp, Tim R. Dafforn, Owen R. T. Thomas
Publié dans: Analytical Chemistry, 2024, ISSN 0003-2700
Éditeur: American Chemical Society
DOI: 10.1021/acs.analchem.4c01882

Conformational analysis of membrane-proximal segments of GDAP1 in a lipidic environment using synchrotron radiation suggests a mode of assembly at the mitochondrial outer membrane

Auteurs: Sutinen, A., Jones, N. C., Hoffmann, S. V., Ruskamo, S., & Kursula, P.
Publié dans: Biophysical Chemistry, Numéro 303, 107113, 2023, ISSN 0301-4622
Éditeur: Elsevier BV
DOI: 10.1016/j.bpc.2023.107113

Monomers, Dimers, and Oligomers of Pyroglutamate-Modified α-Synuclein Fragments Exhibit Distinct Biophysical Characteristics

Auteurs: Alexandra Bluhm, Wei Xiang, Frank Wien, Aurelien Thureau, Maelenn Chevreuil, Bertrand Raynal, Stefanie Geissler, Michael Wermann, Stephan Schilling, Philippe Bénas, Maike Hartlage-Rübsamen, Anja Schulze, Claude Sauter, Steffen Roßner
Publié dans: ACS Chemical Neuroscience, Numéro 16, 2025, Page(s) 1919-1936, ISSN 1948-7193
Éditeur: American Chemical Society
DOI: 10.1021/acschemneuro.5c00106

Substrate-dependent oxidative inactivation of a W-dependent formate dehydrogenase involving selenocysteine displacement

Auteurs: Guilherme Vilela-Alves, Rita R. Manuel, Aldino Viegas, Philippe Carpentier, Frédéric Biaso, Bruno Guigliarelli, Inês A. C. Pereira, Maria João Romão, Cristiano Mota
Publié dans: Chemical Science, Numéro 15, 2024, Page(s) 13090-13101, ISSN 2041-6520
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d4sc02394c

On the synergy between myelin proteins <scp>P</scp>0, <scp>MBP</scp>, and <scp>P</scp>2 in peripheral nerve major dense line formation

Auteurs: Oda C. Krokengen, Arne Raasakka, Martin Berg Klenow, Antara Pal, Øystein Hetland, Anna Mularski, Salla Ruskamo, Jan Skov Pedersen, Adam Cohen Simonsen, Petri Kursula
Publié dans: The FEBS Journal, Numéro 292, 2025, Page(s) 3960-3985, ISSN 1742-464X
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/febs.70111

Assessing the interaction between the N-terminal region of the membrane protein magnesium transporter A and a lipid bilayer

Auteurs: Amanda Eriksson Skog, Nykola C. Jones, Linda K. Månsson, Jens Preben Morth, Søren Vrønning Hoffmann, Yuri Gerelli, Marie Skepö
Publié dans: Journal of Colloid and Interface Science, Numéro 683, 2025, Page(s) 663-674, ISSN 0021-9797
Éditeur: Academic Press
DOI: 10.1016/j.jcis.2024.12.064

How allosteric mutations control ligand binding in Lipocalin protein: odorant binding protein as a test case

Auteurs: Maxence Lalis, Lucie Moitrier, Miriam Jäger, Cornelia Meinert, Marine Brulé, Christine Belloir, Nykola C. Jones, Søren V. Hoffmann, Sébastien Fiorucci, Steffen Wolf, Loïc Briand, Jérémie Topin
Publié dans: Cellular and Molecular Life Sciences, Numéro 82, 2025, ISSN 1420-9071
Éditeur: Springer Science and Business Media LLC
DOI: 10.1007/s00018-025-05777-8

The Amyloid Assembly of the Bacterial Hfq Is Lipid-Driven and Lipid-Specific

Auteurs: Turbant, F., Machiels, Q., Waeytens, J., Wien, F., Arluison, V.
Publié dans: International Journal of Molecular Sciences, 2024, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms25031434

Assessment of protein incorporation into SBA-15 particles and their structural changes

Auteurs: Jessica A. F. Pedro, Luis C. Cides-da-Silva, Tereza S. Martins, Marcia C. A. Fantini, Jose L. S. Lopes
Publié dans: European Biophysics Journal, 2025, ISSN 0175-7571
Éditeur: Springer Verlag
DOI: 10.1007/s00249-025-01801-8

Glycan-induced structural activation softens the human papillomavirus capsid for entry through reduction of intercapsomere flexibility

Auteurs: Yuzhen Feng, Dominik van Bodegraven, Alan Kádek, Ignacio L. B. Munguira, Laura Soria-Martinez, Sarah Nentwich, Sreedeepa Saha, Florian Chardon, Daniel Kavan, Charlotte Uetrecht, Mario Schelhaas, Wouter H. Roos
Publié dans: Nature Communications, Numéro 15, 2024, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-024-54373-0

The Role of Selenocysteine in Catalysis and Oxygen Tolerance of a W-Dependent Formate Dehydrogenase

Auteurs: Ana Rita Oliveira, Guilherme Vilela-Alves, Cristiano Mota, Christophe Léger, Vincent Fourmond, Frédéric Biaso, Bruno Guigliarelli, Maria João Romão, Inês A. Cardoso Pereira
Publié dans: ACS Catalysis, Numéro 15, 2025, Page(s) 12627-12639, ISSN 2155-5435
Éditeur: American Chemical Society
DOI: 10.1021/acscatal.5c02382

Structural insights into the semiquinone form of human Cytochrome P450 reductase by DEER distance measurements between a native flavin and a spin labelled non-canonical amino acid

Auteurs: Bizet, M., Byrne, D., Biaso, F., Gerbaud, G., Etienne, E., Briola, G., Guigliarelli, B., Urban, P., Dorlet, P., Kalai, T., Truan, G., Martinho, M.
Publié dans: Chemistry – A European Journal,, Numéro 30 e202304307, 2024, ISSN 0947-6539
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202304307

Pea and soy protein isolate fractal gels: the role of protein composition, structure and solubility on their gelation behaviour

Auteurs: Tiong, A. Y. J., Crawford, S., Jones, N. C., McKinley, G., Batchelor, W., Hag, L. van ’t
Publié dans: Food Structure, 2024, ISSN 2213-3291
Éditeur: Elsevier BV
DOI: 10.1016/j.foostr.2024.100374

Identification of new ClpC1-NTD binders for Mycobacterium tuberculosis drug development

Auteurs: Katharina Weinhäupl, Louis Meuret, Sandy Desrat, Fanny Roussi, Nelly Morellet, Sandra Beaupierre, Catherine Guillou, Carine van Heijenoort, Olga Abian, Sonia Vega, Ian Wolf, Tatos Akopian, Olga Krandor, Eric Rubin, Adrian Velazquez-Campoy, Diego Gauto, Hugo Fraga
Publié dans: Scientific Reports, Numéro 15, 2025, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-025-87535-1

Molecular dynamics simulations of the adsorption of an intrinsically disordered protein: Force field and water model evaluation in comparison with experiments

Auteurs: Mona Koder Hamid, Linda K. Månsson, Viktoriia Meklesh, Per Persson and Marie Skepö
Publié dans: Frontiers in Molecular Biosciences, Numéro 26 October 2022, 2022, ISSN 2296-889X
Éditeur: Frontiers Media S.A.
DOI: 10.3389/fmolb.2022.958175

Adjuvant Effect of Mesoporous Silica SBA-15 of Different Morphologies on Antidiphtheria Immune Response

Auteurs: Matheus C. R. Miranda, Carmen M. Nunes, Danilo W. Losito, Fernanda M. Rocha, Jéssica A. F. Pedro, Bruna C. Favoretto, Gabriel B. M. Teobaldo, LuÍs Carlos Cides da Silva, Jose L. S. Lopes, Cristiano L. P. Oliveira, Marcia C. A. Fantini, Orlando G. Ribeiro, Osvaldo A. Sant’anna, Tereza S. Martins
Publié dans: ACS Omega, Numéro 10, 2025, Page(s) 27534-27549, ISSN 2470-1343
Éditeur: American Chemical Society (ACS)
DOI: 10.1021/acsomega.5c03459

Enhancing rheological and textural properties of pea protein-collagen gels via transglutaminase crosslinking

Auteurs: Parisa Eslami, Victoria Haritos, Simon Crawford, Leonie van ‘t Hag
Publié dans: Food Structure, Numéro 43, 2025, Page(s) 100409, ISSN 2213-3291
Éditeur: Elsevier BV
DOI: 10.1016/j.foostr.2025.100409

Conserved intramolecular networks in GDAP1 are closely connected to CMT-linked mutations and protein stability

Auteurs: Sutinen, A., Paffenholz, D., Nguyen, G.T.T., Ruskamo, S., Torda, A.E., Kursula, P.
Publié dans: plos One, Numéro 18(4) e0284532, 2023, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0284532

The Landscape of Osteocalcin Proteoforms Reveals Distinct Structural and Functional Roles of Its Carboxylation Sites

Auteurs: Diletta Ami, Carlo Santambrogio, Jacopo Vertemara, Federica Bovio, Andrea Santisteban-Veiga, Juan Sabín, Giuseppe Zampella, Rita Grandori, Laura Cipolla, Antonino Natalello
Publié dans: Journal of the American Chemical Society, Numéro 146, 2024, Page(s) 27755-27769, ISSN 0002-7863
Éditeur: American Chemical Society
DOI: 10.1021/jacs.4c09732

Spectral Profiling of Early αsyn Aggregation in HEK293 Cells Modified to Stably Express Human WT and A53T-αsyn

Auteurs: Priyanka Swaminathan, Karsten Sættem Godø, Eline Bærøe Bjørn, Therése Klingstedt, Debdeep Chatterjee, Per Hammarström, Rajeevkumar Raveendran Nair, Mikael Lindgren
Publié dans: Cells, Numéro 14, 2025, Page(s) 1542, ISSN 2073-4409
Éditeur: MDPI AG
DOI: 10.3390/cells14191542

<i>Mycobacterium tuberculosis</i> sulfurtransferase <scp>SseA</scp> is activated by its neighboring gene product Rv3284

Auteurs: Giulia Di Napoli, Alex Fissore, Edoardo Salladini, Eleonora Raccuia, Simonetta Oliaro‐Bosso, Alessia Ruggiero, Rita Berisio, Milagros Medina, Adrian Velazquez‐Campoy, Salvatore Adinolfi, Mauro Marengo
Publié dans: FEBS Letters, Numéro 599, 2025, Page(s) 2362-2376, ISSN 0014-5793
Éditeur: Elsevier BV
DOI: 10.1002/1873-3468.70117

Chiroptical properties of membrane glycerophospholipids and their chiral backbones

Auteurs: Bocková, J., Garcia, A. D., Jones, N. C., Hoffmann, S. V., Meinert, C.
Publié dans: Chirality, Numéro 36(3), e23654, 2024, ISSN 0899-0042
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/chir.23654

Missense mutations in MMACHC protein from cblC disease affect its conformational stability and vitamin B12-binding activity: The example of R161Q mutation

Auteurs: Lisa Longo, Loredana Randazzo, Michela Bollati, Rita Carrotta, Maria Assunta Costa, Matteo De Rosa, Maria Rosalia Mangione, Vincenzo Martorana, Giulia Culletta, Marco Tutone, Eleonora Mari, Maria Grazia Ortore, Paula M. Garcia-Franco, Adrian Velazquez-Campoy, Rosa Passantino, Silvia Vilasi
Publié dans: Molecular Genetics and Metabolism, Numéro 145, 2025, Page(s) 109150, ISSN 1096-7192
Éditeur: Academic Press
DOI: 10.1016/j.ymgme.2025.109150

Fluorescence labeling methods influence the aggregation process of α-syn in vitro differently

Auteurs: Jadavi, S., Dante, S., Civiero, L., Sandre, M., Bubacco, L., Tosatto, L., Bianchini, P., Canale, C., Diaspro, A.
Publié dans: Nanoscale, Numéro 15, 2023, Page(s) 8270, ISSN 2040-3372
Éditeur: royal society of chemistry
DOI: 10.1039/d2nr05487f

Structural and bioinformatics analyses identify deoxydinucleotide-specific nucleases and their association with genomic islands in gram-positive bacteria

Auteurs: Sofia Mortensen, Stanislava Kuncová, Justin D Lormand, Tanner M Myers, Soo-Kyoung Kim, Vincent T Lee, Wade C Winkler, Holger Sondermann
Publié dans: Nucleic Acids Research, Numéro 53, 2025, ISSN 0305-1048
Éditeur: Oxford University Press
DOI: 10.1093/nar/gkae1235

The human TRPA1 intrinsic cold and heat sensitivity involves separate channel structures beyond the N-ARD domain

Auteurs: Lavanya Moparthi, Viktor Sinica, Vamsi K. Moparthi, Mohamed Kreir, Thibaut Vignane, Milos R. Filipovic, Viktorie Vlachova & Peter M. Zygmunt
Publié dans: Nature communications, Numéro 13:6113, 17 October 2022, 2022, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-022-33876-8

Antimicrobial Activity of an Fmoc-Plantaricin 149 Derivative Peptide against Multidrug-Resistant Bacteria.

Auteurs: Righetto, G.M.; Lopes, J.L.d.S.; Bispo, P.J.M.; André, C.; Souza, J.M.; Andricopulo, A.D.; Beltramini, L.M.; Camargo, I.L.B.d.C.
Publié dans: Anitbiotics, Numéro 12, 2023, Page(s) 391, ISSN 2079-6382
Éditeur: MDPI
DOI: 10.3390/antibiotics12020391

Advantages of a synchrotron light source for fluorescence-detected linear dichroism

Auteurs: Jones, N. C., Rodger, A., Hoffmann, S. V.
Publié dans: Chirality, Numéro 36(4) e23667, 2024, ISSN 0899-0042
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/chir.23667

An allosteric redox switch involved in oxygen protection in a CO2 reductase

Auteurs: Oliveira, A.R., Mota, C., Vilela-Alves, G., Manuel, R.R., Pedrosa, N., Fourmond, V., Klymanska, K., Léger, C., Guigliarelli, B., Romão, M.J., Pereira, I.A.C.
Publié dans: Nature Chemical Biology, Numéro 20, 111-119, 2024, ISSN 1465-7392
Éditeur: Nature Publishing Group
DOI: 10.1038/s41589-023-01484-2

Structural and Functional Characterizationof Proteins Involved in SiderophoreMediated Iron Uptake inErwiniaamylovora

Auteurs: Sharda Bharti
Publié dans: 2024
Éditeur: University of Bolzano

Interactions of intrinsically disordered peptides with phospholipid bilayers

Auteurs: Amanda Eriksson Skog
Publié dans: 2024, ISBN 978-91-8096-071-7
Éditeur: Lund University

Thermodynamic landscape of the redox-centres in the electron-confurcating [FeFe]-Hydrogenase (HydABC) of Thermotoga maritima

Auteurs: Kilian Zuchan, Wolfgang Nitschke, Frauke Baymann, Nina Breuer, James Birell
Publié dans: Biochimica et Biophysica Acta (BBA) - Bioenergetics, Numéro Volume 1863, Supplement, 29, 2022, Page(s) 55, ISSN 0005-2728
Éditeur: Elsevier
DOI: 10.1016/j.bbabio.2022.148757

MOSBRI- A New European Research Infrastructure for Molecular Biophysics

Auteurs: Pierre Dorlet, Guillaume Gerbaud, Emilien Etienne, Stéphane Grimaldi, Bruno Guigliarelli, Valérie Belle.
Publié dans: Biochimica et Biophysica Acta (BBA) - Bioenergetics, Numéro Volume 1863, Supplement 29, 2022, Page(s) 28, ISSN 0005-2728
Éditeur: Elsevier
DOI: 10.1016/j.bbabio.2022.148684

NAD(H)-induced flavosemiquinone stabilization in the electron-confurcating [FeFe]-Hydrogenase (HydABC) of Thermotoga maritima

TNA: Apply for access to laboratories of excellence in molecular scale biophysics research infrastructure (MOSBRI)

Auteurs: Hoffmann, S., Jones, N., Raynal, B., Von Castelmur, E., Derbyshire, D., Sunnerhagen, M.
Publié dans: Acta Crystallographica A – Foundation and Advances, Numéro 78 E350-E350, 2022, ISBN 9780190080112
Éditeur: John Wiley & Sons
DOI: 10.1107/s2053273322093810

4th EBSA congress, July 31 – August 4, 2023, Stockholm, Sweden. Abstract: The MOlecular-Scale Biophysics Research Infrastructure (MOSBRI): a transnational initiative to structure and consolidate the European molecular biophysics community

Auteurs: England, P.
Publié dans: European Biophysics Journal with Biophysical Letters, Numéro 52 S178-S178, 2023
Éditeur: Springer Nature
DOI: 10.1007/s00249-023-01668-7

Advanced in-house X-ray diffraction and scattering instruments as a service for structural biology

Auteurs: Stransky, J., Pavlicek, J., Dohnalek, J.
Publié dans: 2023
Éditeur: John Wiley & Sons
DOI: 10.1107/s2053273322093111

EPR-MRS site: EPR spectroscopy for the study of biomolecules

Auteurs: Pierre Dorlet, Guillaume Gerbaud, Emilien Etienne, Stéphane Grimaldi, Bruno Guigliarelli, Valérie Belle
Publié dans: Biochimica et Biophysica Acta (BBA) - Bioenergetics, Numéro Volume 1863, Supplement 29, 2022, Page(s) 29, ISSN 0005-2728
Éditeur: Elsevier
DOI: 10.1016/j.bbabio.2022.148685

Spectroscopic insights into the mechanism of anamox hydrazine synthase

Auteurs: Wouter Versantvoort, Rainer Hienerwader, Christina Ferousi, Catherine Berthomieu, Laura van Niftrik, Frauke Baymann
Publié dans: Biochimica et Biophysica Acta (BBA) - Bioenergetics, Numéro Volume 1863, Supplement, 29, 2022, Page(s) 76, ISSN 0005-2728
Éditeur: Elsevier
DOI: 10.1016/j.bbabio.2022.148818

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