MOlecular-Scale Biophysics Research Infrastructure

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Dissemination of novel methodologies via website

Dissemination of novel methodologies via websiteDeliverable to be submitted in M12 M24 and M48

Operational proposal system based on ARIA cloud service
Driving licence specifications and test materials at Operator level
MOSBRI website

Report on joint events organized with ARBRE and EBSA

Report on joint events organized with ARBRE and EBSADeliverable to be submitted in M18 M30 and M42

Analysis of the mapping of the needs for data standards/formats

Analysis of the mapping of the needs for data standardsformats

Established reference calibration samples
Analysis of the mapping of the needs for repository/database

Analysis of the mapping of the needs for repositorydatabase

Report on joint events organized with INSTRUCT

Report on joint events organized with INSTRUCTDeliverable to be submitted in M18 M30 and M42

Setting-up of a TNA moderator panel and of a TNA reviewer panel

Pubblicazioni

Multidimensional Decomposition and Ensemble Modeling of Histatin 1 and Its Siblings: Detailing Structure and Biological Function Using an Integrative Approach

Autori: Oskar Svensson, Yuri Gerelli, Marie Skepö
Pubblicato in: Journal of Chemical Information and Modeling, Numero 65, 2025, Pagina/e 7089-7101, ISSN 1549-9596
Editore: American Chemical Society
DOI: 10.1021/acs.jcim.5c00854

Cubosome lipid nanocarriers for delivery of ultra-short antimicrobial peptides

Autori: Biserka Lakic, Chia Beh, Sampa Sarkar, Sue-Lyn Yap, Priscila Cardoso, Celine Valery, Andrew Hung, Nykola C. Jones, Søren Vrønning Hoffmann, Ewan W. Blanch, Brendan Dyett, Charlotte E. Conn
Pubblicato in: Journal of Colloid and Interface Science, Numero 677, 2024, Pagina/e 1080-1097, ISSN 0021-9797
Editore: Academic Press
DOI: 10.1016/j.jcis.2024.07.232

Interaction of a Histidine-Rich Antimicrobial Saliva Peptide with Model Cell Membranes: The Role of Histidines

Autori: Skog, A. E., Corucci, G., Tully, M. D., Fragneto, G., Gerelli, Y., Skepö, M.
Pubblicato in: Langmuir, Numero 39, 2023, Pagina/e 7694, ISSN 1520-5827
Editore: ACS Publications
DOI: 10.1021/acs.langmuir.3c00498

Protein secondary structure determined from independent and integrated infra-red absorbance and circular dichroism data using the algorithm SELCON

Autori: Søren Vrønning Hoffmann, Nykola C. Jones, Alison Rodger
Pubblicato in: QRB Discovery, Numero 6, 2025, ISSN 2633-2892
Editore: Cambridge University Press (CUP)
DOI: 10.1017/qrd.2025.4

Impact of Cellular Crowding on Protein Structural Dynamics Investigated by EPR Spectroscopy

Autori: Annalisa Pierro, Alessio Bonucci, Axel Magalon, Valérie Belle, Elisabetta Mileo
Pubblicato in: Chemical Reviews, Numero 124, 2024, Pagina/e 9873-9898, ISSN 0009-2665
Editore: American Chemical Society
DOI: 10.1021/acs.chemrev.3c00951

Molecular Biophysics Database (MBDB) makes raw measurements findable and reusable

Autori: Emil Dandanell Agerschou, Terezie Prchalová, Miroslav Šimek, Michal Malý, Jan Stránský, Michal Strnad, Andrea Santisteban-Veiga, Mark A. Williams, Juan Sabín, Jan Dohnálek
Pubblicato in: European Biophysics Journal, 2025, ISSN 0175-7571
Editore: Springer Verlag
DOI: 10.1007/s00249-025-01789-1

Plant vs Dairy protein stabilised cappuccino foams: how protein and hydrocolloid conformational changes affect foam stability

Autori: Silvana Wüest, Johann Buczkowski, Nykola C. Jones, Søren Vrønning Hoffmann, Peter Fischer, Tim J. Wooster
Pubblicato in: Food Hydrocolloids, Numero 169, 2025, Pagina/e 111621, ISSN 0268-005X
Editore: Elsevier BV
DOI: 10.1016/j.foodhyd.2025.111621

DNA methylation enhances cooperative disentanglement by the Hfq nucleoid-associated protein

Autori: Frank Wien, Nykola C. Jones, Søren Vrønning Hoffmann, Véronique Arluison
Pubblicato in: European Biophysics Journal, 2025, ISSN 0175-7571
Editore: Springer Verlag
DOI: 10.1007/s00249-025-01800-9

Temoneira-1 beta-lactamase is not a metalloenzyme, but its native metal ion binding sites allow for purification by immobilized metal ion affinity chromatography

Autori: Nafaee, Z.H., Hunyadi-Gulyas, E., Gyurcsik, B.
Pubblicato in: Protein Expression and Purification, 2023, ISSN 1046-5928
Editore: Academic Press
DOI: 10.1016/j.pep.2022.106169

Structure and conformational variability of the HER2-trastuzumab-pertuzumab complex

Autori: Ruedas, R., Vuillemot, R., Tubiana, T., Winter, J. M., Pieri, L., Arteni, A.-A., Samson, C., Jonic, S., Mathieu, M., Bressanelli, S.
Pubblicato in: Journal of Structural Biology, 2024, ISSN 1047-8477
Editore: Academic Press
DOI: 10.1016/j.jsb.2024.108095

Expanding the Diversity of Nitroxide‐Based Paramagnetic Probes Conjugated to Non‐Canonical Amino Acids for Sdsl‐Epr Applications

Autori: Maxime Bizet, Áron Balázsi, Frédéric Biaso, Deborah Byrne, Emilien Etienne, Bruno Guigliarelli, Philippe Urban, Pierre Dorlet, Gilles Truan, Guillaume Gerbaud, Tamás Kálai, Marlène Martinho
Pubblicato in: ChemBioChem, Numero 26, 2025, ISSN 1439-4227
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.202500064

The phosphodiesterase RmcA contributes to the adaptation of Pseudomonas putida to l-arginine

Autori: Scribani-Rossi C, Molina-Henares MA, Angeli S, Cutruzzolà F, Paiardini A, Espinosa-Urgel M, Rinaldo S.
Pubblicato in: FEMS Microbiology Letters, Numero Volume 370, 2023, ISSN 1574-6968
Editore: Oxford university press
DOI: 10.1093/femsle/fnad077

Electrochemical Kinetics Support a Second Coordination Sphere Mechanism in Metal-Based Formate Dehydrogenase

Autori: Marta Meneghello, Alexandre Uzel, Marianne Broc, Rita R. Manuel, Axel Magalon, Christophe Léger, Inês A. C. Pereira, Anne Walburger, Vincent Fourmond
Pubblicato in: Angewandte Chemie - International edition, Numero 134, e202299999, 2022, ISSN 1521-3773
Editore: Wiley-VCH GmbH
DOI: 10.1002/anie.202212224

ProteinLIPs: a web server for identifying highly polar and poorly packed interfaces in proteins

Autori: Helena García-Cebollada, Alfonso López, Vladimir E Angarica, Juan José Galano-Frutos, Javier Sancho
Pubblicato in: Bioinformatics, Numero 41, 2025, ISSN 1367-4803
Editore: Oxford University Press
DOI: 10.1093/bioinformatics/btaf499

Visualizing Molecular Dynamics by High-Speed Atomic Force Microscopy

Autori: van Ewijk, C., Maity, S., Roos, W.H.
Pubblicato in: Single Molecule Analysis . Methods in Molecular Biology, 2023, ISSN 1064-3745
Editore: Humana Press, Inc.
DOI: 10.1007/978-1-0716-3377-9_17

Interactions and Insertion of Escherichia coli Hfq into Outer Membrane Vesicles as Revealed by Infrared and Orientated Circular Dichroism Spectroscopies

Autori: Turbant, F., Waeytens, J., Blache, A., Esnouf, E., Raussens, V., Wegrzyn, G., Achouak, W., Wien, F., Arluison, V.
Pubblicato in: International Journal of Molecular Sciences, Numero 24(14), 11424, 2023, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms241411424

Despite the odds: formation of the SARS-CoV-2 methylation complex

Autori: Matsuda, A., Plewka, J., Rawski, M., Mourão, A., Zajko, W., Siebenmorgen, T., Kresik, L., Lis, K., Jones, A. N., Pachota, M., Karim, A., Hartman, K., Nirwal, S., Sonani, R., Chykunova,Y., Minia, I., Mak, P., Landthaler, M., Nowotny, M., Dubin, G., Sattler, M., Suder, P., Popowicz, G. M., Pyrć, K., Czarna, A.
Pubblicato in: Nucleic Acids Research, 2024, ISSN 1362-4962
Editore: Oxford university press
DOI: 10.1093/nar/gkae165

Lateral membrane organization as target of an antimicrobial peptidomimetic compound

Autori: Melcrova, A., Maity, S., Melcr, J., de Kok, N.A.W., Gabler, M., van der Eyden, J., Stensen, W., Svendsen, J.S.M., Driessen, A.J.M., Marrink, S.J., Roos, W.H.
Pubblicato in: Nature Communications, Numero 14(1) ar4038, 2023, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-023-39726-5

Influence of the enzymatic treatment and pH on the interfacial and emulsifying properties of sunflower and olive protein hydrolysates

Autori: Pérez-Gálvez, R., Maldonado-Valderrama, J., Jones, N. C., Hoffmann, S. V., Guadix, E., García-Moreno, P. J.
Pubblicato in: Food Hydrocolloids, Numero 154 ar110135, 2024, ISSN 0268-005X
Editore: Elsevier BV
DOI: 10.1016/j.foodhyd.2024.110135

Modifying recombinant purple acid phosphatase using computational design

Autori: Aishwarya Venkatramani, Montader Ali, Olga Predeina, Jennifer C. Molloy, Pietro Sormanni, Elizabeth A. H. Hall
Pubblicato in: European Biophysics Journal, 2025, ISSN 0175-7571
Editore: Springer Verlag
DOI: 10.1007/s00249-025-01779-3

13th EBSA congress, July 24–28, 2021, Vienna, Austria

Autori: 13th EBSA congress
Pubblicato in: European Biophysics Journal, Numero 50/S1, 2021, Pagina/e 1-226, ISSN 0175-7571
Editore: Springer Verlag
DOI: 10.1007/s00249-021-01558-w

Protein Microarrays for High Throughput Hydrogen/Deuterium Exchange Monitored by FTIR Imaging

Autori: Joëlle De Meutter, Erik Goormaghtigh
Pubblicato in: International Journal of Molecular Sciences, Numero 25, 2025, Pagina/e 9989, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms25189989

ATR-FTIR Biosensors for Antibody Detection and Analysis

Autori: Suys, O., Derenne, A., Goormaghtigh, E.
Pubblicato in: International Journal of Molecular Sciences, Numero 23(19), 2022, Pagina/e 11895, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms231911895

Spectroscopic insights into the mechanism of anammox hydrazine synthase

Autori: Wouter Versantvoort, Rainer Hienerwadel, Christina Ferousi, Pieter van der Velden, Catherine Berthomieu, Laura van Niftrik, Frauke Baymann
Pubblicato in: Journal of Biological Chemistry, Numero 301, 2025, Pagina/e 110771, ISSN 0021-9258
Editore: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.jbc.2025.110771

Biochemical characterization of L-asparaginase isoforms from Rhizobium etli—the boosting effect of zinc

Autori: Sliwiak, J., Worsztynowicz, P., Pokrywka, K., Loch, J. I., Grzechowiak, M., Jaskolski, M.
Pubblicato in: Frontiers in Chemistry, 2024, ISSN 2296-2646
Editore: Frontiers Media S.A
DOI: 10.3389/fchem.2024.1373312

Protein Structural Denaturation Evaluated by MCR-ALS of Protein Microarray FTIR Spectra

Autori: De Meutter, J., Goormaghtigh, E.
Pubblicato in: Analytical Chemistry, Numero 93(40), 2021, Pagina/e 13441-13449, ISSN 1520-6882
Editore: American Chemical Society publications
DOI: 10.1021/acs.analchem.1c01416

Molecular insights into RmcA-mediated c-di-GMP consumption: Linking redox potential to biofilm morphogenesis in Pseudomonas aeruginosa

Autori: Scribani Rossi, C., Eckartt, K., Scarchilli, E., Angeli, S., Price-Whelan, A., Di Matteo, A., Chevreuil, M., Raynal, B., Arcovito, A., Giacon, N., Fiorentino, F., Rotili, D.,
Pubblicato in: Microbiological Research, Numero Volume 277, 127498, 2023, ISSN 1618-0623
Editore: Elsevier
DOI: 10.1016/j.micres.2023.127498

In Vitro Cell Model Investigation of Alpha-Synuclein Aggregate Morphology Using Spectroscopic Imaging

Autori: Priyanka Swaminathan, Therése Klingstedt, Vasileios Theologidis, Hjalte Gram, Johan Larsson, Lars Hagen, Nina B. Liabakk, Odrun A. Gederaas, Per Hammarström, K. Peter R. Nilsson, Nathalie Van Den Berge, Mikael Lindgren
Pubblicato in: International Journal of Molecular Sciences, Numero 25, 2025, Pagina/e 12458, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms252212458

Modulation of conformational features and oligomerization of MMACHC by cobalamin variants: impact of the R161Q mutation in cblC disease

Autori: Lisa Longo, Maria Assunta Costa, Rita Carrotta, Maria Rosalia Mangione, Vincenzo Martorana, Marco Tutone, Maria Grazia Ortore, Paula M. Garcia-Franco, Sonia Vega, Adrian Velazquez-Campoy, Rosa Passantino, Silvia Vilasi
Pubblicato in: European Biophysics Journal, 2025, ISSN 0175-7571
Editore: Springer Verlag
DOI: 10.1007/s00249-025-01777-5

Merging multi-omics with proteome integral solubility alteration unveils antibiotic mode of action

Autori: Ritwik Maity, Xuepei Zhang, Francesca Romana Liberati, Chiara Scribani Rossi, Francesca Cutruzzolá, Serena Rinaldo, Massimiliano Gaetani, José Antonio Aínsa, Javier Sancho
Pubblicato in: eLife, Numero 13, 2024, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.96343.3

Synthesis of 3,4-Disubstituted Pyrroline Nitroxides Containing Diphenylphosphane or Diphenylphosphane Oxide Substituents

Autori: Balázsi, A., Bognár, B., Jeko, J., Kálai, T.
Pubblicato in: SynOpen, 2024, ISSN 2509-9396
Editore: Thieme
DOI: 10.1055/a-2264-8302

ChiraKit: an online tool for the analysis of circular dichroism spectroscopy data

Autori: Osvaldo Burastero, Nykola C Jones, Lucas A Defelipe, Uroš Zavrtanik, San Hadži, Søren Vrønning Hoffmann, Maria M Garcia-Alai
Pubblicato in: Nucleic Acids Research, Numero 53, 2025, Pagina/e W158-W168, ISSN 0305-1048
Editore: Oxford University Press
DOI: 10.1093/nar/gkaf350

Contact-free characterization of nuclear mechanics using correlative Brillouin-Raman Micro-Spectroscopy in living cells

Autori: S. Kerdegari, A.A. Passeri, F. Morena, G. Ciccone, V. Bazzurro, P. Canepa, A. Lagomarsino, S. Martino, M. Mattarelli, M. Vassalli, A. Diaspro, S. Caponi, C. Canale
Pubblicato in: Acta Biomaterialia, Numero 198, 2025, Pagina/e 291-301, ISSN 1742-7061
Editore: Elsevier BV
DOI: 10.1016/j.actbio.2025.04.009

Raynals, an online tool for the analysis of dynamic light scattering.

Autori: Burastero, O., Draper-Barr, G., Raynal, B., Chevreuil, M., England, P., Garcia-Alai, M.
Pubblicato in: Acta Crystallographica Section D, Numero 79, 2023, Pagina/e p673–683, ISSN 2059-7983
Editore: IUCr journals
DOI: 10.1107/s2059798323004862

Exploring the Metabolic Response of Pseudomonas putida to L-arginine

Autori: Scribani-Rossi, C., Molina-Henares, M. A., Espinosa-Urgel, M., Rinaldo, S.
Pubblicato in: Advances in Experimental Medicine and Biology, 2024, ISSN 0065-2598
Editore: Kluwer Academic/Plenum Publishers
DOI: 10.1007/5584_2024_797

Membrane-Active Antibiotics Affect Domains in Bacterial Membranes as the First Step of Their Activity

Autori: Adéla Melcrová, Christiaan Klein, Wouter H. Roos
Pubblicato in: Nano Letters, Numero 24, 2024, Pagina/e 11800-11807, ISSN 1530-6984
Editore: American Chemical Society
DOI: 10.1021/acs.nanolett.4c01873

Limited high-throughput screening compatibility of the phenuivirus cap-binding domain

Autori: Scherf, J., Vogel, D., Gul, S., Reinshagen, J., Gribbon, P., Rosenthal, M.
Pubblicato in: Scientific Reports, Numero 13, 2023, Pagina/e 22820, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-023-50158-5

Use of emulsifying plant protein hydrolysates from winery, whiskey and brewery by-products for the development of echium oil delivery emulsions

Autori: Mariana Sisconeto Bisinotto, Inar Castro, Julia Maldonado-Valderrama, Nykola C. Jones, Teresa del Castillo-Santaella, Søren Vrønning Hoffmann, Emilia M. Guadix, Pedro J. García-Moreno
Pubblicato in: International Journal of Biological Macromolecules, Numero 308, 2025, Pagina/e 142736, ISSN 0141-8130
Editore: Elsevier BV
DOI: 10.1016/j.ijbiomac.2025.142736

SidF, a dual substrate N5-acetyl-N5-hydroxy-L-ornithine transacetylase involved in Aspergillus fumigatus siderophore biosynthesis

Autori: Thanalai Poonsiri, Jan Stransky, Nicola Demitri, Hubertus Haas, Michele Cianci, Stefano Benini
Pubblicato in: Journal of Structural Biology: X, Numero 11, 2025, Pagina/e 100119, ISSN 2590-1524
Editore: Elsevier BV
DOI: 10.1016/j.yjsbx.2024.100119

Guidelines for the Simulations of Nitroxide X-Band cw EPR Spectra from Site-Directed Spin Labeling Experiments Using SimLabel

Autori: Etienne, E., Pierro, A., Tamburrini, K. C., Bonucci, A., Mileo, E., Martinho, M., Belle, V.
Pubblicato in: Molecules, Numero 28, 2023, Pagina/e 1348, ISSN 1420-3049
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules28031348

Effect of Cholesterol on Biomimetic Membrane Curvature and Coronavirus Fusion Peptide Encapsulation

Autori: Milogrodzka, I., Pham, D.T.N., Sama, G.R., Samadian, H., Zhai, J.L., de Campo, L., Kirby, N.M., Scott, T.F., Holl, M.M.B., van’t Hag, L.
Pubblicato in: ACS Nano, Numero 17 (9), 2023, Pagina/e 8598-8612, ISSN 1936-0851
Editore: American Chemical Society
DOI: 10.1021/acsnano.3c01095

Direct Observation of Secondary Nucleation in Huntingtin Amyloid Formation by High-Speed Atomic Force Microscopy

Autori: Chris van Ewijk, Greeshma Jain, Yari K. Knelissen, Sourav Maity, Patrick C. A. van der Wel, Wouter H. Roos
Pubblicato in: Journal of the American Chemical Society, Numero 147, 2025, Pagina/e 21973-21984, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.5c05571

The Fluorescent Amyloid Ligand X34 Binding to Transthyretin (TTR) Tetramer and Fibrils: FRET and Binding Constants of a Sequential Two‐step Process

Autori: Marikken Sundnes, Priyanka Swaminathan, Mikael Lindgren, Ganesh Mohite, Ebba Hellstrand, Sofie Nyström, Per Hammarström
Pubblicato in: ChemPhotoChem, Numero 9, 2025, ISSN 2367-0932
Editore: Wiley
DOI: 10.1002/cptc.202400249

The cytoplasmic tail of myelin protein zero induces morphological changes in lipid membranes

Autori: Oda C. Krokengen, Christine Touma, Anna Mularski, Aleksi Sutinen, Ryan Dunkel, Marie Ytterdal, Arne Raasakka, Haydyn D.T. Mertens, Adam Cohen Simonsen, Petri Kursula
Pubblicato in: Biochimica et Biophysica Acta (BBA) - Biomembranes, Numero 1866, 2025, Pagina/e 184368, ISSN 0005-2736
Editore: Elsevier BV
DOI: 10.1016/j.bbamem.2024.184368

In-cell investigation of the conformational landscape of the GTPase UreG by SDSL-EPR

Autori: Pierro, A., Tamburrini, K.C., Leguenno, H., Gerbaud, G., Etienne, E., Guigliarelli, B., Belle, V., Zambelli, B., Mileo, E.
Pubblicato in: iScience, Numero 26(10), 2023, Pagina/e 107855, ISSN 2589-0042
Editore: cell press
DOI: 10.1016/j.isci.2023.107855

Analysis of the Structure of 14 Therapeutic Antibodies Using Circular Dichroism Spectroscopy

Autori: Maria G. Bruque, Alison Rodger, Søren Vrønning Hoffmann, Nykola C. Jones, Jean Aucamp, Tim R. Dafforn, Owen R. T. Thomas
Pubblicato in: Analytical Chemistry, 2024, ISSN 0003-2700
Editore: American Chemical Society
DOI: 10.1021/acs.analchem.4c01882

Conformational analysis of membrane-proximal segments of GDAP1 in a lipidic environment using synchrotron radiation suggests a mode of assembly at the mitochondrial outer membrane

Autori: Sutinen, A., Jones, N. C., Hoffmann, S. V., Ruskamo, S., & Kursula, P.
Pubblicato in: Biophysical Chemistry, Numero 303, 107113, 2023, ISSN 0301-4622
Editore: Elsevier BV
DOI: 10.1016/j.bpc.2023.107113

Monomers, Dimers, and Oligomers of Pyroglutamate-Modified α-Synuclein Fragments Exhibit Distinct Biophysical Characteristics

Autori: Alexandra Bluhm, Wei Xiang, Frank Wien, Aurelien Thureau, Maelenn Chevreuil, Bertrand Raynal, Stefanie Geissler, Michael Wermann, Stephan Schilling, Philippe Bénas, Maike Hartlage-Rübsamen, Anja Schulze, Claude Sauter, Steffen Roßner
Pubblicato in: ACS Chemical Neuroscience, Numero 16, 2025, Pagina/e 1919-1936, ISSN 1948-7193
Editore: American Chemical Society
DOI: 10.1021/acschemneuro.5c00106

Substrate-dependent oxidative inactivation of a W-dependent formate dehydrogenase involving selenocysteine displacement

Autori: Guilherme Vilela-Alves, Rita R. Manuel, Aldino Viegas, Philippe Carpentier, Frédéric Biaso, Bruno Guigliarelli, Inês A. C. Pereira, Maria João Romão, Cristiano Mota
Pubblicato in: Chemical Science, Numero 15, 2024, Pagina/e 13090-13101, ISSN 2041-6520
Editore: Royal Society of Chemistry
DOI: 10.1039/d4sc02394c

On the synergy between myelin proteins <scp>P</scp>0, <scp>MBP</scp>, and <scp>P</scp>2 in peripheral nerve major dense line formation

Autori: Oda C. Krokengen, Arne Raasakka, Martin Berg Klenow, Antara Pal, Øystein Hetland, Anna Mularski, Salla Ruskamo, Jan Skov Pedersen, Adam Cohen Simonsen, Petri Kursula
Pubblicato in: The FEBS Journal, Numero 292, 2025, Pagina/e 3960-3985, ISSN 1742-464X
Editore: Blackwell Publishing Inc.
DOI: 10.1111/febs.70111

Assessing the interaction between the N-terminal region of the membrane protein magnesium transporter A and a lipid bilayer

Autori: Amanda Eriksson Skog, Nykola C. Jones, Linda K. Månsson, Jens Preben Morth, Søren Vrønning Hoffmann, Yuri Gerelli, Marie Skepö
Pubblicato in: Journal of Colloid and Interface Science, Numero 683, 2025, Pagina/e 663-674, ISSN 0021-9797
Editore: Academic Press
DOI: 10.1016/j.jcis.2024.12.064

How allosteric mutations control ligand binding in Lipocalin protein: odorant binding protein as a test case

Autori: Maxence Lalis, Lucie Moitrier, Miriam Jäger, Cornelia Meinert, Marine Brulé, Christine Belloir, Nykola C. Jones, Søren V. Hoffmann, Sébastien Fiorucci, Steffen Wolf, Loïc Briand, Jérémie Topin
Pubblicato in: Cellular and Molecular Life Sciences, Numero 82, 2025, ISSN 1420-9071
Editore: Springer Science and Business Media LLC
DOI: 10.1007/s00018-025-05777-8

The Amyloid Assembly of the Bacterial Hfq Is Lipid-Driven and Lipid-Specific

Autori: Turbant, F., Machiels, Q., Waeytens, J., Wien, F., Arluison, V.
Pubblicato in: International Journal of Molecular Sciences, 2024, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms25031434

Assessment of protein incorporation into SBA-15 particles and their structural changes

Autori: Jessica A. F. Pedro, Luis C. Cides-da-Silva, Tereza S. Martins, Marcia C. A. Fantini, Jose L. S. Lopes
Pubblicato in: European Biophysics Journal, 2025, ISSN 0175-7571
Editore: Springer Verlag
DOI: 10.1007/s00249-025-01801-8

Glycan-induced structural activation softens the human papillomavirus capsid for entry through reduction of intercapsomere flexibility

Autori: Yuzhen Feng, Dominik van Bodegraven, Alan Kádek, Ignacio L. B. Munguira, Laura Soria-Martinez, Sarah Nentwich, Sreedeepa Saha, Florian Chardon, Daniel Kavan, Charlotte Uetrecht, Mario Schelhaas, Wouter H. Roos
Pubblicato in: Nature Communications, Numero 15, 2024, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-024-54373-0

The Role of Selenocysteine in Catalysis and Oxygen Tolerance of a W-Dependent Formate Dehydrogenase

Autori: Ana Rita Oliveira, Guilherme Vilela-Alves, Cristiano Mota, Christophe Léger, Vincent Fourmond, Frédéric Biaso, Bruno Guigliarelli, Maria João Romão, Inês A. Cardoso Pereira
Pubblicato in: ACS Catalysis, Numero 15, 2025, Pagina/e 12627-12639, ISSN 2155-5435
Editore: American Chemical Society
DOI: 10.1021/acscatal.5c02382

Structural insights into the semiquinone form of human Cytochrome P450 reductase by DEER distance measurements between a native flavin and a spin labelled non-canonical amino acid

Autori: Bizet, M., Byrne, D., Biaso, F., Gerbaud, G., Etienne, E., Briola, G., Guigliarelli, B., Urban, P., Dorlet, P., Kalai, T., Truan, G., Martinho, M.
Pubblicato in: Chemistry – A European Journal,, Numero 30 e202304307, 2024, ISSN 0947-6539
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202304307

Pea and soy protein isolate fractal gels: the role of protein composition, structure and solubility on their gelation behaviour

Autori: Tiong, A. Y. J., Crawford, S., Jones, N. C., McKinley, G., Batchelor, W., Hag, L. van ’t
Pubblicato in: Food Structure, 2024, ISSN 2213-3291
Editore: Elsevier BV
DOI: 10.1016/j.foostr.2024.100374

Identification of new ClpC1-NTD binders for Mycobacterium tuberculosis drug development

Autori: Katharina Weinhäupl, Louis Meuret, Sandy Desrat, Fanny Roussi, Nelly Morellet, Sandra Beaupierre, Catherine Guillou, Carine van Heijenoort, Olga Abian, Sonia Vega, Ian Wolf, Tatos Akopian, Olga Krandor, Eric Rubin, Adrian Velazquez-Campoy, Diego Gauto, Hugo Fraga
Pubblicato in: Scientific Reports, Numero 15, 2025, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-025-87535-1

Molecular dynamics simulations of the adsorption of an intrinsically disordered protein: Force field and water model evaluation in comparison with experiments

Autori: Mona Koder Hamid, Linda K. Månsson, Viktoriia Meklesh, Per Persson and Marie Skepö
Pubblicato in: Frontiers in Molecular Biosciences, Numero 26 October 2022, 2022, ISSN 2296-889X
Editore: Frontiers Media S.A.
DOI: 10.3389/fmolb.2022.958175

Adjuvant Effect of Mesoporous Silica SBA-15 of Different Morphologies on Antidiphtheria Immune Response

Autori: Matheus C. R. Miranda, Carmen M. Nunes, Danilo W. Losito, Fernanda M. Rocha, Jéssica A. F. Pedro, Bruna C. Favoretto, Gabriel B. M. Teobaldo, LuÍs Carlos Cides da Silva, Jose L. S. Lopes, Cristiano L. P. Oliveira, Marcia C. A. Fantini, Orlando G. Ribeiro, Osvaldo A. Sant’anna, Tereza S. Martins
Pubblicato in: ACS Omega, Numero 10, 2025, Pagina/e 27534-27549, ISSN 2470-1343
Editore: American Chemical Society (ACS)
DOI: 10.1021/acsomega.5c03459

Enhancing rheological and textural properties of pea protein-collagen gels via transglutaminase crosslinking

Autori: Parisa Eslami, Victoria Haritos, Simon Crawford, Leonie van ‘t Hag
Pubblicato in: Food Structure, Numero 43, 2025, Pagina/e 100409, ISSN 2213-3291
Editore: Elsevier BV
DOI: 10.1016/j.foostr.2025.100409

Conserved intramolecular networks in GDAP1 are closely connected to CMT-linked mutations and protein stability

Autori: Sutinen, A., Paffenholz, D., Nguyen, G.T.T., Ruskamo, S., Torda, A.E., Kursula, P.
Pubblicato in: plos One, Numero 18(4) e0284532, 2023, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0284532

The Landscape of Osteocalcin Proteoforms Reveals Distinct Structural and Functional Roles of Its Carboxylation Sites

Autori: Diletta Ami, Carlo Santambrogio, Jacopo Vertemara, Federica Bovio, Andrea Santisteban-Veiga, Juan Sabín, Giuseppe Zampella, Rita Grandori, Laura Cipolla, Antonino Natalello
Pubblicato in: Journal of the American Chemical Society, Numero 146, 2024, Pagina/e 27755-27769, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.4c09732

Spectral Profiling of Early αsyn Aggregation in HEK293 Cells Modified to Stably Express Human WT and A53T-αsyn

Autori: Priyanka Swaminathan, Karsten Sættem Godø, Eline Bærøe Bjørn, Therése Klingstedt, Debdeep Chatterjee, Per Hammarström, Rajeevkumar Raveendran Nair, Mikael Lindgren
Pubblicato in: Cells, Numero 14, 2025, Pagina/e 1542, ISSN 2073-4409
Editore: MDPI AG
DOI: 10.3390/cells14191542

<i>Mycobacterium tuberculosis</i> sulfurtransferase <scp>SseA</scp> is activated by its neighboring gene product Rv3284

Autori: Giulia Di Napoli, Alex Fissore, Edoardo Salladini, Eleonora Raccuia, Simonetta Oliaro‐Bosso, Alessia Ruggiero, Rita Berisio, Milagros Medina, Adrian Velazquez‐Campoy, Salvatore Adinolfi, Mauro Marengo
Pubblicato in: FEBS Letters, Numero 599, 2025, Pagina/e 2362-2376, ISSN 0014-5793
Editore: Elsevier BV
DOI: 10.1002/1873-3468.70117

Chiroptical properties of membrane glycerophospholipids and their chiral backbones

Autori: Bocková, J., Garcia, A. D., Jones, N. C., Hoffmann, S. V., Meinert, C.
Pubblicato in: Chirality, Numero 36(3), e23654, 2024, ISSN 0899-0042
Editore: John Wiley & Sons Inc.
DOI: 10.1002/chir.23654

Missense mutations in MMACHC protein from cblC disease affect its conformational stability and vitamin B12-binding activity: The example of R161Q mutation

Autori: Lisa Longo, Loredana Randazzo, Michela Bollati, Rita Carrotta, Maria Assunta Costa, Matteo De Rosa, Maria Rosalia Mangione, Vincenzo Martorana, Giulia Culletta, Marco Tutone, Eleonora Mari, Maria Grazia Ortore, Paula M. Garcia-Franco, Adrian Velazquez-Campoy, Rosa Passantino, Silvia Vilasi
Pubblicato in: Molecular Genetics and Metabolism, Numero 145, 2025, Pagina/e 109150, ISSN 1096-7192
Editore: Academic Press
DOI: 10.1016/j.ymgme.2025.109150

Fluorescence labeling methods influence the aggregation process of α-syn in vitro differently

Autori: Jadavi, S., Dante, S., Civiero, L., Sandre, M., Bubacco, L., Tosatto, L., Bianchini, P., Canale, C., Diaspro, A.
Pubblicato in: Nanoscale, Numero 15, 2023, Pagina/e 8270, ISSN 2040-3372
Editore: royal society of chemistry
DOI: 10.1039/d2nr05487f

Structural and bioinformatics analyses identify deoxydinucleotide-specific nucleases and their association with genomic islands in gram-positive bacteria

Autori: Sofia Mortensen, Stanislava Kuncová, Justin D Lormand, Tanner M Myers, Soo-Kyoung Kim, Vincent T Lee, Wade C Winkler, Holger Sondermann
Pubblicato in: Nucleic Acids Research, Numero 53, 2025, ISSN 0305-1048
Editore: Oxford University Press
DOI: 10.1093/nar/gkae1235

The human TRPA1 intrinsic cold and heat sensitivity involves separate channel structures beyond the N-ARD domain

Autori: Lavanya Moparthi, Viktor Sinica, Vamsi K. Moparthi, Mohamed Kreir, Thibaut Vignane, Milos R. Filipovic, Viktorie Vlachova & Peter M. Zygmunt
Pubblicato in: Nature communications, Numero 13:6113, 17 October 2022, 2022, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-022-33876-8

Antimicrobial Activity of an Fmoc-Plantaricin 149 Derivative Peptide against Multidrug-Resistant Bacteria.

Autori: Righetto, G.M.; Lopes, J.L.d.S.; Bispo, P.J.M.; André, C.; Souza, J.M.; Andricopulo, A.D.; Beltramini, L.M.; Camargo, I.L.B.d.C.
Pubblicato in: Anitbiotics, Numero 12, 2023, Pagina/e 391, ISSN 2079-6382
Editore: MDPI
DOI: 10.3390/antibiotics12020391

Advantages of a synchrotron light source for fluorescence-detected linear dichroism

Autori: Jones, N. C., Rodger, A., Hoffmann, S. V.
Pubblicato in: Chirality, Numero 36(4) e23667, 2024, ISSN 0899-0042
Editore: John Wiley & Sons Inc.
DOI: 10.1002/chir.23667

An allosteric redox switch involved in oxygen protection in a CO2 reductase

Autori: Oliveira, A.R., Mota, C., Vilela-Alves, G., Manuel, R.R., Pedrosa, N., Fourmond, V., Klymanska, K., Léger, C., Guigliarelli, B., Romão, M.J., Pereira, I.A.C.
Pubblicato in: Nature Chemical Biology, Numero 20, 111-119, 2024, ISSN 1465-7392
Editore: Nature Publishing Group
DOI: 10.1038/s41589-023-01484-2

Structural and Functional Characterizationof Proteins Involved in SiderophoreMediated Iron Uptake inErwiniaamylovora

Autori: Sharda Bharti
Pubblicato in: 2024
Editore: University of Bolzano

Interactions of intrinsically disordered peptides with phospholipid bilayers

Autori: Amanda Eriksson Skog
Pubblicato in: 2024, ISBN 978-91-8096-071-7
Editore: Lund University

Thermodynamic landscape of the redox-centres in the electron-confurcating [FeFe]-Hydrogenase (HydABC) of Thermotoga maritima

Autori: Kilian Zuchan, Wolfgang Nitschke, Frauke Baymann, Nina Breuer, James Birell
Pubblicato in: Biochimica et Biophysica Acta (BBA) - Bioenergetics, Numero Volume 1863, Supplement, 29, 2022, Pagina/e 55, ISSN 0005-2728
Editore: Elsevier
DOI: 10.1016/j.bbabio.2022.148757

MOSBRI- A New European Research Infrastructure for Molecular Biophysics

Autori: Pierre Dorlet, Guillaume Gerbaud, Emilien Etienne, Stéphane Grimaldi, Bruno Guigliarelli, Valérie Belle.
Pubblicato in: Biochimica et Biophysica Acta (BBA) - Bioenergetics, Numero Volume 1863, Supplement 29, 2022, Pagina/e 28, ISSN 0005-2728
Editore: Elsevier
DOI: 10.1016/j.bbabio.2022.148684

NAD(H)-induced flavosemiquinone stabilization in the electron-confurcating [FeFe]-Hydrogenase (HydABC) of Thermotoga maritima

TNA: Apply for access to laboratories of excellence in molecular scale biophysics research infrastructure (MOSBRI)

Autori: Hoffmann, S., Jones, N., Raynal, B., Von Castelmur, E., Derbyshire, D., Sunnerhagen, M.
Pubblicato in: Acta Crystallographica A – Foundation and Advances, Numero 78 E350-E350, 2022, ISBN 9780190080112
Editore: John Wiley & Sons
DOI: 10.1107/s2053273322093810

4th EBSA congress, July 31 – August 4, 2023, Stockholm, Sweden. Abstract: The MOlecular-Scale Biophysics Research Infrastructure (MOSBRI): a transnational initiative to structure and consolidate the European molecular biophysics community

Autori: England, P.
Pubblicato in: European Biophysics Journal with Biophysical Letters, Numero 52 S178-S178, 2023
Editore: Springer Nature
DOI: 10.1007/s00249-023-01668-7

Advanced in-house X-ray diffraction and scattering instruments as a service for structural biology

Autori: Stransky, J., Pavlicek, J., Dohnalek, J.
Pubblicato in: 2023
Editore: John Wiley & Sons
DOI: 10.1107/s2053273322093111

EPR-MRS site: EPR spectroscopy for the study of biomolecules

Autori: Pierre Dorlet, Guillaume Gerbaud, Emilien Etienne, Stéphane Grimaldi, Bruno Guigliarelli, Valérie Belle
Pubblicato in: Biochimica et Biophysica Acta (BBA) - Bioenergetics, Numero Volume 1863, Supplement 29, 2022, Pagina/e 29, ISSN 0005-2728
Editore: Elsevier
DOI: 10.1016/j.bbabio.2022.148685

Spectroscopic insights into the mechanism of anamox hydrazine synthase

Autori: Wouter Versantvoort, Rainer Hienerwader, Christina Ferousi, Catherine Berthomieu, Laura van Niftrik, Frauke Baymann
Pubblicato in: Biochimica et Biophysica Acta (BBA) - Bioenergetics, Numero Volume 1863, Supplement, 29, 2022, Pagina/e 76, ISSN 0005-2728
Editore: Elsevier
DOI: 10.1016/j.bbabio.2022.148818

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