Descripción del proyecto
Dispositivo portátil para la detección en tiempo real de la COVID-19
A medida que el mundo se prepara para la segunda ola del coronavirus de rápida propagación, ha surgido la prioridad mundial de contar con herramientas de diagnóstico precisas. Junto con el aislamiento y el rastreo, las pruebas a gran escala de ciudadanos están demostrando ser lo más eficaz en el control de la COVID-19. Sin embargo, se necesitan tecnologías adecuadas y sólidas para lograr resultados rápidos en la protección de la población. Por este motivo, en el proyecto financiado con fondos europeos IRIS-COV se propone una tecnología basada en un dispositivo portátil patentado con amplificación isotérmica mediada por bucle y detección colorimétrica cuantitativa en tiempo real, que ha demostrado tener una sensibilidad del 97,4 % y una especificidad del 100 % para el coronavirus del síndrome respiratorio agudo grave de tipo 2 en las muestras. El equipo del proyecto validará y certificará el dispositivo portátil para la detección de la COVID-19 y de la gripe directamente en muestras brutas y de forma inmediata, con el objetivo de que se utilice en todo el mundo.
Objetivo
The current pandemic of the coronavirus, reported first on 31st December 2019 in China, has produced a global alert of unprecedented nature. From the beginning, immediate actions have been put in place by all relevant stakeholders, i.e. local health departments, governments, pharmaceutical companies, global organisations etc., to address the problem as quickly as possible and control the spread of the disease. Large scale testing of symptomatic and asymptomatic patients/citizens has been one of the most effective measures taken by several countries, combined with isolation and tracking. Today, after six months from the outbreak, the deaths continue to rise with over 200 affected countries. Fear of a new wave of the pandemic together with the ongoing cases worldwide make the need for developing rapid and accurate diagnostic tools for COVID-19 a global priority, as declared by the WHO. The current consortium aims to join forces in the battle against the coronavirus by producing mature and robust solutions with immediate impact. The proposal is built around the implementation of an existing and patented device and methodology based on isothermal LAMP amplification and real time quantitative colorimetric detection. This mature methodology, currently of a technology readiness level of 7, has already been proven to be able to detect SARS-CoV-2 in patients’ samples with 97.4% sensitivity and 100% specificity. The main objectives of this proposal are thus the immediate deployment of the device following clinical validation and fast track certification. Arrangements for the large-scale production of the device and reagents will take place in parallel, followed by the provision of a full medical certification for COVID-19 and flu detection directly in crude samples and at the point-of-care. Global uptake of the two certified products together with global sharing of the project results are important deliverables of the proposal for the current and future epidemics.
Ámbito científico
Palabras clave
Programa(s)
Convocatoria de propuestas
H2020-SC1-PHE-CORONAVIRUS-2020-2
Consulte otros proyectos de esta convocatoriaConvocatoria de subcontratación
H2020-SC1-PHE-CORONAVIRUS-2020-2-CNECT
Régimen de financiación
IA - Innovation actionCoordinador
70013 Irakleio
Grecia