Description du projet
Un dispositif portable pour la détection en temps réel de la COVID-19
Alors que le monde se prépare à la deuxième vague du coronavirus, des outils de diagnostic précis sont devenus une priorité mondiale. Avec l’isolement et le suivi, le dépistage à grande échelle des citoyens s’avère être le moyen le plus efficace de contrôler la COVID-19. Toutefois, des solutions de test appropriées et solides sont nécessaires pour obtenir rapidement des résultats en matière de protection des populations. C’est pourquoi le projet IRIS-COV, financé par l’UE, propose une solution basée sur un dispositif portable breveté avec amplification LAMP isotherme et détection colorimétrique quantitative en temps réel, qui s’est révélée sensible à 97,4 % et spécifique à 100 % pour le SARS-CoV-2 dans les échantillons. Le projet validera et certifiera le dispositif portable de détection de la COVID-19 et de la grippe directement dans les échantillons bruts et sur le lieu de soins, en vue de son adoption à l’échelle mondiale.
Objectif
The current pandemic of the coronavirus, reported first on 31st December 2019 in China, has produced a global alert of unprecedented nature. From the beginning, immediate actions have been put in place by all relevant stakeholders, i.e. local health departments, governments, pharmaceutical companies, global organisations etc., to address the problem as quickly as possible and control the spread of the disease. Large scale testing of symptomatic and asymptomatic patients/citizens has been one of the most effective measures taken by several countries, combined with isolation and tracking. Today, after six months from the outbreak, the deaths continue to rise with over 200 affected countries. Fear of a new wave of the pandemic together with the ongoing cases worldwide make the need for developing rapid and accurate diagnostic tools for COVID-19 a global priority, as declared by the WHO. The current consortium aims to join forces in the battle against the coronavirus by producing mature and robust solutions with immediate impact. The proposal is built around the implementation of an existing and patented device and methodology based on isothermal LAMP amplification and real time quantitative colorimetric detection. This mature methodology, currently of a technology readiness level of 7, has already been proven to be able to detect SARS-CoV-2 in patients’ samples with 97.4% sensitivity and 100% specificity. The main objectives of this proposal are thus the immediate deployment of the device following clinical validation and fast track certification. Arrangements for the large-scale production of the device and reagents will take place in parallel, followed by the provision of a full medical certification for COVID-19 and flu detection directly in crude samples and at the point-of-care. Global uptake of the two certified products together with global sharing of the project results are important deliverables of the proposal for the current and future epidemics.
Champ scientifique
Programme(s)
Appel à propositions
H2020-SC1-PHE-CORONAVIRUS-2020-2
Voir d’autres projets de cet appelSous appel
H2020-SC1-PHE-CORONAVIRUS-2020-2-CNECT
Régime de financement
IA - Innovation actionCoordinateur
70013 Irakleio
Grèce