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CORDIS - Forschungsergebnisse der EU
CORDIS

LETHE (λήθη) – A personalized prediction and intervention model for early detection and reduction of risk factors causing dementia, based on AI and distributed Machine Learning

CORDIS bietet Links zu öffentlichen Ergebnissen und Veröffentlichungen von HORIZONT-Projekten.

Links zu Ergebnissen und Veröffentlichungen von RP7-Projekten sowie Links zu einigen Typen spezifischer Ergebnisse wie Datensätzen und Software werden dynamisch von OpenAIRE abgerufen.

Leistungen

LETHE Interoperability Framework (öffnet in neuem Fenster)

This deliverable defines the interoperability frameworks and provides possible modules or interfaces needed FHIR API eg

Study protocol (öffnet in neuem Fenster)

Description of the detailed study protocol

Long-term data collection report (öffnet in neuem Fenster)

This deliverable provides the data and description of the long term data used for the LETHE model extension

Report on PPI activities and impact I (öffnet in neuem Fenster)

This deliverable provides a report I of the activities regarding Public an Patient Involvement

Dissemination and Communication plan (öffnet in neuem Fenster)

This report includes the dissemination and communication plan of the consortium as a whole and of each single partner distributed in progressive phases

Detailed evaluation plan for the pilot's assessment and evaluation (including metrics) (öffnet in neuem Fenster)

This deliverable provides an updated version of the MAFEIP framework to be used to evaluate the pilots

LETHE architecture and scenarios (öffnet in neuem Fenster)

This deliverables provides the a first version of technical architecture defining all modules as responsibilities as well as interfaces and responsibilities for the validation trials

LETHE architecture update (öffnet in neuem Fenster)

This deliverables provides the final technical architecture updating interfaces based on learnings from the validation trials

Pilot site set up results (öffnet in neuem Fenster)

Finalized side setup and report

Recommendations on social and ethical implications of the project (öffnet in neuem Fenster)

This deliverable provides recommendations about end user related social and ethical implications of the project

LETHE deployment setup and handbook (öffnet in neuem Fenster)

This deliverable defines the LETHE deployment including a description of a LETHE setup roll out

Privacy and legal framework I (öffnet in neuem Fenster)

This deliverable will describe all the ethics and related legal aspects relevant for the project the associated actions and responsibilities already in place and to be implemented in the Data Management plan and will assess the impact in terms of fundamental rights data protection and privacy of the methods proposed in the context of the project

Communication Media pack for the LETHE project (öffnet in neuem Fenster)

Report of communication channels activated eg videos flyers banners social media and relevant KPIs achieved

Project Website (öffnet in neuem Fenster)

Web site for internal and external communication

Knowledge-base Model (öffnet in neuem Fenster)

This deliverable contains the implemented model as well as the description of the knowledge base model for data stream annotation.

Deployment of the LETHE infrastructure (öffnet in neuem Fenster)

This will be the service prototype, with a report to outline the final set-up of the cloud-based infrastructure for the LETHE project including the EOSC services tailored and links to open-source repositories of software used to address the project needs

LETHE sensing ecosystem (öffnet in neuem Fenster)

The deliverable presents in detail the sensing ecosystem of Lethe along with the supporting services.

Data Management plan and ORDP I (öffnet in neuem Fenster)

This deliverable will provide a general outline of the project policy for data management and describe the data management life cycle for all data sets that will be collected processed or generated by the LETHE project A first version of a data management plan DMP will furthermore provide the data protection policy for the project as well as justification for the collection and processing of sensitive personal data The DMP will as well describe technical and organizational measures that will be implemented to safeguard the rights and freedoms of the data subjectsresearch participants and in detail information on the informed consent procedures with regards to data processing as well as description of the anonymysation pseudonymisation techniques that will be implementedIn the case of research involves observation of the participants the respective beneficiaries will provide explanation how the data subjects will be informed of the existence of the monitoring its possible consequences and how their fundamental rights will be safeguardedIn case of further processing of previously collected personal data an explicit confirmation that the involved beneficiaries have lawful basis for the data processing and that the appropriate technical and organisational measures are in place to safeguard the rights of the data subjectsThe results of the performed comprehensive Data Protection Impact Assessments DPIAs in order to assess any potential risks arising from the processing activities planned and to assess the effectiveness of the technical and organisational measures taken for the protection of the rights and freedoms of the data subjects will be provided in this deliverable and updated in D62Concluding this deliverable will sum up and present in a concise manner the compliance datasheet and measures taken for all data collected processed stored and shared in accordance to GDPR and will adhere to the privacy principles regarding data collection and processing With the first version of the deliverable the Data Protection Officer DPO for all host institutions institutions where data are generated will be appointed and contact details given In this deliverable all beneficiaries involved in processing data will check if special derogations pertaining to the rights of data subjects or the processing of genetic biometric andor health data have been established under the national legislation of the country where the research takes place and submit a declaration of compliance with respective national legal frameworks Furthermore the respective beneficiaries will explain how all of the data they intend to process are relevant and limited to the purposes of the research project in accordance with the data minimisation principleThe Deliverable includes also the selection of research data to be provided with open access according OpenAire and EOSC prescriptions

Veröffentlichungen

Psycho-social impact of the diagnostic work-up at a specialized, fast-track memory clinic.

Autoren: Alara Abaci, Heleen M.A. Hendriksen, Malin Aspö, Maria Sundell, Fleur Wiggenraad, Marie Rydén, Miia Kivipelto, Wiesje M. van der Flier, Francesca Mangialasche, Leonie N.C. Visser
Veröffentlicht in: Alzheimer's Association International Conference, 2023
Herausgeber: Alzheimer's Association International Conference

Dementia prevention through personalized prediction and intervention, based on Artificial Intelligence and Machine Learning (LETHE): study design of a feasibility trial

Autoren: Anna Rosenberg, Jenni Lehtisalo, Jeroen Bruinsma, Markus Bödenler, Matteo Colombo, Rik Crutzen, Ana Diaz, Dimitrios, Anna Giulia Guazzarini, Jyrki Lötjönen, Bernhard Neumayer, Mattia Pirani, Bianca Schnalzer, Helena Untersteiner, Sten Hanke, Miia Kivipelto, Francesca Mangialasche, Patrizia Mecocci, Elisabeth Stögmann, Tiia Ngandu,
Veröffentlicht in: 9TH KUOPIO ALZHEIMER SYMPOSIUM AND 3RD NORDIC MEMORY CLINIC CONFERENCE: PROGRAM AND ABSTRACTS, 2022, Seite(n) 88-89, ISSN 1798-5730
Herausgeber: University of Eastern Finland

Aivoterveyden edistämisen ajankohtaiset teemat

Autoren: Anna Rosenberg
Veröffentlicht in: Gerontologia Tampere 2023, 2023
Herausgeber: Gerontologia Tampere 2023

Integration of health initiatives with tools and services under the European Open Science Cloud (LETHE, FEMaLe and HealthyCloud) - workshop

Autoren: Ville Tenhunen, Francesco Mureddu, Juan Gonzalez-Garcia, Dmitrijs Bļizņuks
Veröffentlicht in: EGI Conference 2022, 2022
Herausgeber: EGI Conference 2022

LETHE: A Digital Intervention for Cognitive Decline

Autoren: Vasileios Loukas, Thomas Kassiotis, Ignacio Lamata Martinez, Lefteris Koumakis, Jeroen Bruinsma, Roberto Pasciuti, Monica Balatresi, Ville Tenhunen, Adam Fiakkas, Lelia Ataliani, Georgia Karanasiou, Manolis Tsiknakis, Hannes Hilberger, Markus Bödenler, Bianca Katharina Schnalzer, Simone Huber, Mattia Pirani, Matteo Colombo, Sten Hanke, Dimitrios I. Fotiadis
Veröffentlicht in: International Conference of the IEEE Engineering in Medicine and Biology Society, 2023
Herausgeber: International Conference of the IEEE Engineering in Medicine and Biology Society

WW-FINGERS updates: towards personalized prevention and global strategies

Autoren: Miia Kivipelto
Veröffentlicht in: 9TH KUOPIO ALZHEIMER SYMPOSIUM AND 3RD NORDIC MEMORY CLINIC CONFERENCE: PROGRAM AND ABSTRACTS, 2022, Seite(n) 68
Herausgeber: University of Eastern Finland

Digitally supported lifestyle program to promote brain health among older adults (LETHE pilot trial) – Study design and progress

Autoren: Anna Rosenberg, Helena Untersteiner, Anna Giulia Guazzarini, Jenni Lehtisalo, Charlotta Thunborg, Jeroen Bruinsma, Matteo Colombo, Rik Crutzen, Ana Diaz, Dimitrios Fotiadis, Hannes Hilberger, Simone Huber, Miia Kivipelto, Vassilis Loukas, Jyrki Lötjönen, Mattia Pirani, Bianca Schnalzer, Sten Hanke, Francesca Mangialasche, Patrizia Mecocci, Elisabeth Stögmann,Tiia Ngandu, LETHE Consortium
Veröffentlicht in: Alzheimer's Association International Conference, 2023
Herausgeber: Alzheimer's Association International Conference

Motivations of patients and their care partners for visiting a memory clinic. A qualitative study (öffnet in neuem Fenster)

Autoren: Leonie N.C. Visser; Agnetha Fruijtier; Marleen Kunneman; Femke H. Bouwman; Niki Schoonenboom; Salka S. Staekenborg; Hilje A. Wind; Liesbeth Hempenius; Marlijn H. de Beer; Gerwin Roks; Leo Boelaarts; Mariska Kleijer; Ellen M.A. Smets; Wiesje M. van der Flier
Veröffentlicht in: VOLUME=111;ISSN=0738-3991;TITLE=Patient Education and Counseling, Ausgabe 2, 2023, ISSN 0738-3991
Herausgeber: Elsevier BV
DOI: 10.1016/j.pec.2023.107693

The public’s perspectives on lifestyle-related behavior change for dementia risk reduction: a qualitative study (öffnet in neuem Fenster)

Autoren: Jeroen BruinsmaIrene HegerVassilis LoukasThomas KassiotisGeorgia KaranasiouDimitrios I. FotiadisSten HankeRik Crutzen
Veröffentlicht in: Journal of Alzheimer's Disease, 2023, ISSN 1387-2877
Herausgeber: IOS Press
DOI: 10.31219/osf.io/7jp6u

Federated Learning with Dynamic Model Exchange (öffnet in neuem Fenster)

Autoren: Sten Hanke; Hannes Hilberger; Markus Bödenler
Veröffentlicht in: Electronics; Volume 11; Ausgabe 10; Pages: 1530, 2022, ISSN 2079-9292
Herausgeber: MDPI electronics
DOI: 10.3390/electronics11101530

AI-Based Predictive Modelling of the Onset and Progression of Dementia (öffnet in neuem Fenster)

Autoren: Sten Hanke; Francesca Mangialasche; Markus Bödenler; Bernhard Neumayer; Tiia Ngandu; Patrizia Mecocci; Helena Untersteiner; Elisabeth Stögmann
Veröffentlicht in: Smart Cities; Volume 5; Ausgabe 2; Pages: 700-714, Ausgabe 5, 2022, ISSN 2624-6511
Herausgeber: MDPI Smart Cities
DOI: 10.3390/smartcities5020036

Dementia prevention through personalized prediction and intervention, basedon Artificial Intelligence and Machine Learning (LETHE): study design of a feasibility trial - Oral presentation

Autoren: Anna Rosenberg
Veröffentlicht in: 32 Alzheimer Europe Conference, 2022
Herausgeber: 32 Alzheimer Europe Conference

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