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Genomics and Personalized Medicine for all though Artificial Intelligence in Haematological Diseases

Objective

GENOMED4ALL will support the pooling of genomic, clinical data and other “-omics” health data (data EHR, PET, MRI and CT , Next Generation Sequencing, Microarray, Genome Wide Association, Copy Number Variations, DNA sequencing, RNA sequencing, including single cell, etc.) through a secure and privacy respectful data sharing platform based on the novel Federated Learning scheme, to advance research in personalised medicine in haematological diseases thanks to advanced novel AI models and standardized sharing of cross-border data. GENOMED4ALL will make use of the existing infrastructures and initiatives, including powerful High Performance Computing facilities, hospital registries, data processing tools, and pre-existing repositories, starting from 10 clinical partners repositories to be enlarged especially by the resources provided by ERN-EuroBloodNet where GENOMED4ALL clinical partners have a leading position, which contain 66 relevant clinical sites providing repositories and knowledge, for the successful exploitation of genomics, clinical and other related “-omics” data to facilitate personalised medicine in common, rare and ultrarare haematological diseases to demonstrate the versatility and utility of the solutions, and 20 external of this network.
GENOMED4ALL will demonstrate the potential and benefits of trustable and explainable AI technologies, with a novel approach to AI models and algorithms using AI advanced deep learning, variational autoencoders, generative models, besides combining with advanced statistical and Machine learning processes approaches to exploit the powerful set of “-omics” data which will be at researchers’ disposal. This will allow for identifying new knowledge, to support clinical research and decision making by linking Europe's relevant genomic repositories in haematological diseases, while ensuring full compliance with data protection legislation and ethical principles, and increasing the AI trust for personalized medicine.

Field of science

  • /natural sciences/computer and information sciences/computer security/data protection
  • /natural sciences/computer and information sciences/data science/data processing
  • /humanities/philosophy, ethics and religion/ethics/ethical principles
  • /natural sciences/computer and information sciences/artificial intelligence/machine learning/deep learning

Call for proposal

H2020-SC1-FA-DTS-2020-1
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

UNIVERSIDAD POLITECNICA DE MADRID
Address
Calle Ramiro De Maeztu 7 Edificio Rectorado
28040 Madrid
Spain
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 869 375

Participants (22)

LIFE TECHNOLOGIES GmbH
Germany
EU contribution
€ 412 500
Address
Frankfurter Strasse 129 B
64293 Darmstadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
DXC TECHNOLOGY SERVICIOS ESPANA SL
Spain
EU contribution
€ 782 325
Address
Calle Jose Echegaray 8, Las Rozas
28232 Madrid
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
DATAWIZARD SRL
Italy
EU contribution
€ 628 750
Address
Via Salaria 719
00138 Roma
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
AUSTRALO INTERINNOV MARKETING LAB SL
Spain
EU contribution
€ 348 500
Address
Cl Pompeu Fabra 1 2 4
08860 Castelldefel
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
THE EUROPEAN INSTITUTE FOR INNOVATION THROUGH HEALTH DATA
Belgium
EU contribution
€ 337 500
Address
Oude Mechelsestraat 165
1853 Strombeek-bever
Activity type
Research Organisations
HUMANITAS MIRASOLE SPA
Italy
EU contribution
€ 702 500
Address
Via Manzoni 56
20100 Rozzano (Mi)
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA
Spain
EU contribution
€ 434 000
Address
Passeig Vall D Hebron 119-129 Edificio De Recerca
08035 Barcelona
Activity type
Research Organisations
ASSISTANCE PUBLIQUE HOPITAUX DE PARIS
France
EU contribution
€ 437 918,75
Address
3 Avenue Victoria
75000 Paris
Activity type
Research Organisations
MLL MUNCHNER LEUKAMIELABOR GMBH
Germany
EU contribution
€ 300 000
Address
Max Lebsche Platz 31
81377 Munchen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands
EU contribution
€ 380 250
Address
Heidelberglaan 100
3584 CX Utrecht
Activity type
Higher or Secondary Education Establishments
GERENCIA REGIONAL DE SALUD DE CASTILLA Y LEON
Spain
EU contribution
€ 192 500
Address
Paseo De Zorrilla 1
47007 Valladolid
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
THE CYPRUS FOUNDATION FOR MUSCULAR DYSTROPHY RESEARCH
Cyprus
EU contribution
€ 330 250
Address
International Airport Avenue 6
1683 Ayios Dometios
Activity type
Research Organisations
UNIVERSITA DEGLI STUDI DI PADOVA
Italy
EU contribution
€ 223 750
Address
Via 8 Febbraio 2
35122 Padova
Activity type
Higher or Secondary Education Establishments
UNIVERSITAET LEIPZIG
Germany
EU contribution
€ 264 625
Address
Ritterstrasse 26
04109 Leipzig
Activity type
Higher or Secondary Education Establishments
ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON
Greece
EU contribution
€ 384 000
Address
6 Christou Lada Str
10561 Athina
Activity type
Higher or Secondary Education Establishments
ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA
Italy
EU contribution
€ 739 995
Address
Via Zamboni 33
40126 Bologna
Activity type
Higher or Secondary Education Establishments
KOBENHAVNS UNIVERSITET
Denmark
EU contribution
€ 410 625
Address
Norregade 10
1165 Kobenhavn
Activity type
Higher or Secondary Education Establishments
FUNDACIO CENTRE DE REGULACIO GENOMICA
Spain
EU contribution
€ 615 125
Address
Carrer Doctor Aiguader 88
08003 Barcelona
Activity type
Research Organisations
UNIVERSITA DEGLI STUDI DI TORINO
Italy
EU contribution
€ 271 875
Address
Via Giuseppe Verdi 8
10124 Torino
Activity type
Higher or Secondary Education Establishments
IDRYMA TECHNOLOGIAS KAI EREVNAS
Greece
EU contribution
€ 396 875
Address
N Plastira Str 100
70013 Irakleio
Activity type
Research Organisations
CHAMBRE DE COMMERCE ET D'INDUSTRIE DE REGION PARIS ILE-DE-FRANCE
France
EU contribution
€ 153 325
Address
Avenue De Friedland 27
75382 Paris
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
CINECA CONSORZIO INTERUNIVERSITARIO
Italy
EU contribution
€ 382 500
Address
Via Magnanelli 6/3
40033 Casalecchio Di Reno Bo
Activity type
Research Organisations